Comprehensive Training Program in Oral Biology

口腔生物学综合培训计划

• 批准号: 10414198
• 负责人: Jose A Lemos
• 金额: $ 8.88万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10414198
• 关键词: Appointment; Area; Autoimmunity; Biology; Biomedical Engineering; Clinical; Clinical Sciences; Communicable Diseases; Computational Biology; Dental; Dentistry; Detection; Disease; Doctor of Philosophy; Ethics; Florida; Goals; Head and Neck Cancer; Health; Human; Human Microbiome; Individual; Institutes; Interdisciplinary Study; Knowledge; Medicine; Mouth Diseases; National Institute of Dental and Craniofacial Research; Oral; Oral health; Postdoctoral Fellow; Prevention; Prevention strategy; Preventive therapy; Research; Research Personnel; Resources; Salivary Glands; Science; Scientist; Students; Technology; Training; Training Programs; Translating; Translational Research; Universities; Work; biomedical informatics; bone; career; clinical investigation; college; craniofacial; craniofacial complex; doctoral student; experience; flexibility; high standard; implementation outcomes; implementation science; improved; novel; oral biology; oral infection; post-doctoral training; programs; response; stem cell biology; treatment strategy; virology

Contact PD/PI: Lemos, Jose A ABSTRACT In response to PAR-20-056 from the NIDCR to develop and enhance the Dental, Oral and Craniofacial Research Workforce, a T90/R90 Comprehensive Training Program in Oral Biology is proposed. The proposal builds on 29 years of experience with highly productive T32 and T90/R90 Training Programs at the University of Florida College of Dentistry (UFCD) and will provide extensive breadth and depth in training to basic and clinician scientists in multiple areas that are designated as high priority by the NIDCR. The scientific areas encompassed in this Comprehensive Training Program in Oral Biology include, but are not limited to, the Human Microbiome, Oral Infectious Diseases, Mechanistic Connections between Oral and Systemic Health, Virology, Salivary Gland Biology, Autoimmunity, Bone Biology, Head and Neck Cancers, Computational Biology, Biomedical Engineering, and Stem Cell Biology. To accomplish our goals, a team of accomplished basic and clinical researchers has been assembled to provide an extensive set of training experiences in the biomedical sciences that are directly relevant to oral health and diseases. Well-established interdisciplinary research training programs in the UFCD and the UF College of Medicine will be utilized, with particular emphasis on the Interdisciplinary PhD Program in Biomedical Sciences and the UF Clinical and Translational Science Institute (CTSI). Trainees will include i) 3 traditional PhD students conducting oral health-related research, ii) 4 dual-degree candidates in our DMD-PhD program, iii) 2 post-doctoral scientists (T90; PhD, DMD/DDS-PhD, DMD/DDS), and iv) 1 non-citizen, non-permanent resident DMD-PhD holders seeking advanced post-doctoral training (R90) to prepare them for careers in academic dentistry. In most cases, PhD and postdoctoral trainees will receive an initial commitment for appointments of three or two years, respectively, whereas dual-degree students will be supported for the duration of their training. Additional formal training in Clinical Investigation, Implementation Science or Biomedical Informatics will be available to individuals supported by the program. The use of combinations of our extensive educational, scientific, and clinical resources has allowed us to develop highly integrated yet sufficiently flexible training options to meet the needs of a very diverse group of trainees. Collectively, these programs will produce highly skilled and interactive scientists who can engage in team science to generate new knowledge and translate discoveries to tangible advances in the detection, prevention, treatment and cures of diseases and abnormalities of the oral and craniofacial complex. Project Summary/Abstract Page 6 Contact PD/PI: Lemos, Jose A NARRATIVE There is a critical need for a diverse group of highly trained basic and clinical oral health researchers. If effective preventive therapies and cures for the many diseases associated with the oral, dental and craniofacial complex are to be discovered and applied, a cadre of oral health researchers must be trained to work in interdisciplinary teams and to maintain the highest standards for ethical and responsible conduct of rigorous scientific research. The main objective of this comprehensive training program is to produce oral health researchers who can apply state-of-the-art technologies to generate new knowledge, translate that information to applied therapies, and rigorously evaluate the outcomes of implementation of novel preventive or treatment strategies to improve human health.

联系人 PD/PI：Lemos、Jose A 抽象的 响应 NIDCR 的 PAR-20-056，开发和增强牙科、口腔和颅面护理 研究人员提出了口腔生物学 T90/R90 综合培训计划。提案 建立在 29 年大学高效 T32 和 T90/R90 培训计划经验的基础上 佛罗里达牙科学院 (UFCD) 将为基础和牙医提供广泛、广度和深度的培训 被 NIDCR 指定为高度优先的多个领域的临床科学家。科学领域 本口腔生物​​学综合培训计划包括但不限于 人类微生物组、口腔传染病、口腔与全身健康之间的机制联系、 病毒学、唾液腺生物学、自身免疫、骨生物学、头颈癌、计算 生物学、生物医学工程和干细胞生物学。为了实现我们的目标，一支由有成就的团队组成 聚集了基础和临床研究人员，提供了广泛的培训经验 与口腔健康和疾病直接相关的生物医学科学。完善的跨学科 将利用 UFCD 和 UF 医学院的研究培训项目，特别是 强调生物医学科学和佛罗里达大学临床和转化的跨学科博士课程 科学研究所（CTSI）。受训人员将包括 i) 3 名传统博士生，进行口腔健康相关研究 研究，ii) 4 名 DMD-PhD 项目双学位候选人，iii) 2 名博士后科学家（T90；PhD， DMD/DDS-PhD、DMD/DDS)，以及 iv) 1 名非公民、非永久居民 DMD-PhD 持有者寻求 高级博士后培训（R90），为他们从事学术牙科职业做好准备。在大多数情况下，博士 博士后培训生将收到三年或两年的初步承诺， 分别，而双学位学生将在培训期间获得支持。附加正式 将提供临床研究、实施科学或生物医学信息学方面的培训 受该计划支持的个人。结合我们广泛的教育、科学和 临床资源使我们能够开发高度集成但足够灵活的培训选项来满足 非常多样化的学员群体的需求。总的来说，这些项目将培养高技能和 互动科学家，他们可以参与团队科学来产生新知识并将发现转化为 在口腔疾病和异常的检测、预防、治疗和治愈方面取得切实进展 和颅面复合体。 项目总结/摘要第 6 页 联系人 PD/PI：Lemos、Jose A 叙述 迫切需要一批训练有素的基础和临床口腔健康研究人员。如果 有效预防和治疗与口腔、牙齿和颅面相关的许多疾病 要发现和应用复杂的口腔健康研究人员，必须培训一支口腔健康研究人员骨干队伍，以便他们能够在 跨学科团队，并保持严格的道德和负责任行为的最高标准 科学研究。该综合培训计划的主要目标是培养口腔健康 研究人员能够应用最先进的技术来生成新知识并翻译该信息 应用疗法，并严格评估实施新型预防或治疗的结果 改善人类健康的策略。