Tennessee Center for AIDS Research (TN-CFAR)

田纳西州艾滋病研究中心 (TN-CFAR)

基本信息

批准号：
10404928
负责人：
SIMON Alexander MALLAL
金额：
$ 241.58万
依托单位：
VANDERBILT UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-04-01 至 2025-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10404928
关键词：
AIDS/HIV problem Academic Medical Centers Acquired Immunodeficiency Syndrome Address Affect African American population Area Caring Collaborations Communities Data Development Disease Outbreaks Doctor of Philosophy Environment Epidemic Extramural Activities Fostering Funding Goals HIV HIV Infections HIV Seronegativity Health Health Sciences Institution Knowledge Laws Leadership Medical Minority Groups Mission Needle-Exchange Programs Persons Populations at Risk Postdoctoral Fellow Public Policy Research Research Personnel Resources Rural Science Scientist Southeastern United States Tennessee Underserved Population United States United States National Institutes of Health Vision Work base career development community engaged research community engagement community partnership dashboard design experience falls high risk implementation science improved medical schools multidisciplinary next generation novel prevent success surveillance data synergism tool translational impact working group

项目摘要

Overall – PROJECT SUMMARY Decades of research have generated knowledge and tools with the potential to prevent all new HIV infections, to ultimately end the HIV epidemic in the United States and worldwide, and to improve the lives of people living with HIV. To date, reality has fallen short of these goals, in part due to pressing unmet needs. The Tennessee Center for AIDS Research (CFAR) is located in the Southeastern United States, the region with the greatest number of new HIV infections, and of persons living with HIV. This CFAR was established in 2015, under the leadership of Prof. Simon Mallal, as a three-way partnership between a research-intensive medical institution (Vanderbilt University Medical Center, VUMC), a historically black medical college (Meharry Medical College, MMC), and an academically engaged state health department (Tennessee Department of Health, TDH). This partnership has fostered collaborations that would be unimaginable without CFAR. For example, results of an analysis by VUMC and MMC investigators using TDH surveillance data has affected statewide public policy and law regarding needle exchange, reducing the likelihood of a potentially devastating HIV outbreak in rural Tennessee. To end the epidemic, it is becoming increasingly important to pursue community-engaged research, to include both people living with HIV and those at high risk. Toward this end, this CFAR has newly partnered with a fourth institution, Nashville CARES, a sophisticated community-based organization with a 25-year exclusive focus on people living with HIV and those at high risk. Through this four-way partnership, our vision is to have transformative, local and global translational impact. Guided by this vision, our mission is to coordinate the complementary institutional and community strengths and resources of VUMC, MMC, TDH and CARES to most effectively reduce the burden of HIV/AIDS and generalize these benefits nationally and globally. Work of this CFAR aligns with National Institutes of Health high priorities for NIH/AIDS research. To fulfill our mission, this CFAR will pursue four specific aims: 1) To support multidisciplinary HIV research that leverages the highly collaborative local environment to build impactful team science among the four institutions of the CFAR; 2) To nurture and support career development of junior investigators, so as to grow the number and diversity of the next generation of HIV researchers; 3) To specifically enable HIV research opportunities for MMC investigators, to include engagement with investigators and resources across the CFAR, and leveraging team science; and 4) To continue to grow a broad emphasis on HIV-focused community-engaged research that pervades the CFAR, and with a focus on ending the epidemic.

总体而言——项目摘要数十年的研究已经产生了有潜力预防所有新的艾滋病毒感染的知识和工具，最终结束美国和世界范围内的艾滋病毒流行，并改善人们的生活迄今为止，现实尚未实现这些目标，部分原因是田纳西州的迫切需求未得到满足。艾滋病研究中心（CFAR）位于美国东南部，该地区是艾滋病研究最多的地区。该 CFAR 于 2015 年根据《艾滋病毒新发感染者数量》和《艾滋病毒感染者数量》建立。 Simon Mallal 教授的领导下，作为研究密集型医疗机构之间的三向合作伙伴关系（范德比尔特大学医学中心，VUMC），一所历史悠久的黑人医学院（梅哈里医学院， MMC），以及从事学术工作的州卫生部门（田纳西州卫生部门，TDH）。伙伴关系促进了没有 CFAR 就无法想象的合作。 VUMC 和 MMC 调查人员使用 TDH 监测数据进行的分析已经影响了总体公共政策和关于针头交换的法律，减少了农村地区潜在的毁灭性艾滋病毒爆发的可能性田纳西州，为了结束这种流行病，进行社区参与的研究变得越来越重要，为此，CFAR 与艾滋病病毒感染者和高危人群建立了新的合作伙伴关系。与第四个机构 Nashville CARES 合作，这是一个成熟的社区组织，拥有 25 年的历史通过这种四向合作伙伴关系，我们的愿景是关注艾滋病毒感染者和高危人群。在这一愿景的指导下，我们的使命是协调。 VUMC、MMC、TDH 和 CARES 的机构互补性以及社区优势和资源最有效地减轻艾滋病毒/艾滋病的负担，并将这些好处推广到全国和全球。该 CFAR 与美国国立卫生研究院 (NIH)/艾滋病研究的高度优先事项一致，以履行我们的使命，该CFAR将追求四个具体目标：1）支持多学科艾滋病毒研究，充分利用当地协作环境，在 CFAR 的四个机构之间建立有影响力的团队科学 2) 培养和支持初级研究者的职业发展，以增加初级研究者的数量和多样性下一代 HIV 研究人员；3) 专门为 MMC 研究人员提供 HIV 研究机会，包括与整个 CFAR 的研究人员和资源进行互动，并利用团队科学；4) 为了继续广泛重视遍及 CFAR 的以艾滋病毒为重点的社区参与研究，并重点关注结束疫情。