Using partners to enhance long-term weight loss

利用合作伙伴来促进长期减肥

基本信息

批准号：
10396455
负责人：
Corrine Ione Voils
金额：
$ 56.29万
依托单位：
UNIVERSITY OF WISCONSIN-MADISON
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-07-20 至 2024-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10396455
关键词：
Address Adult Affect Age Behavior Behavior Therapy Behavioral Body Weight decreased Body mass index Caloric Restriction Car Phone Communication Coping Behavior Coping Skills Counseling Couples Diet Diet Monitoring Dietary intake Domestic Partners Educational process of instructing Effectiveness Eligibility Determination Energy Intake Evaluation Fatty acid glycerol esters Frequencies Future Goals Health Health Care Costs Health behavior change Health system Individual Insurance Carriers Intake Intervention Joints Knowledge Learning Life Style Maintenance Mediating Mediation Mediator of activation protein Methodology Modeling Monitor Motivation Obesity Outcome Overweight Participant Patient-Focused Outcomes Patients Persons Pharmaceutical Preparations Physical Function Physical activity Prevalence Quality of life Randomized Relapse Risk Factors Role Social Environment Social support Source Specific qualifier value Spouses Telephone Testing Text Messaging Training United States Visit Weight Weight Gain Weight maintenance regimen Work arm bariatric surgery base behavior change cardiovascular disorder risk clinically significant commune comorbidity coping cost effective cost effectiveness design dietary dietary restriction disorder later incidence prevention efficacy outcomes efficacy testing evidence base hypercholesterolemia improved insight intervention effect novel obesity treatment patient subsets preventable death primary outcome programs secondary outcome skills skills training theories treatment as usual weight loss program weight maintenance

项目摘要

Abstract Obesity is the second leading cause of preventable deaths in the United States. Weight loss, and maintenance of weight loss, improves cardiovascular disease risk factors, physical functioning, and quality of life. Interventions that combine dietary change, physical activity increase, and behavioral strategies are efficacious for short-term weight loss but less so for long-term weight loss. Given that the best predictor of long-term weight loss is initial weight loss, strategies are needed to enhance both initial weight loss and weight loss maintenance. Dietary and physical activity behaviors often are influenced by domestic partners. Therefore, intervening jointly on patients and their partners is likely to improve the efficacy of weight management programs. This study involves an evaluation of the role of domestic partner support in a comprehensive weight loss initiation and maintenance program. Eligibility criteria include age 18-75, BMI ≥27 kg/m2 with an obesity- related comorbidity or BMI ≥30 kg/m2, and cohabitating with a domestic partner. 230 couples will be randomized to 18-month comprehensive weight program directed at patients alone or involving their partners. In months 1-6, all patients will receive group-based weight loss program featuring a calorie-restricted diet and physical activity. In months 7-18, all patients will receive a weight loss maintenance intervention that involves maintenance-specific content, transitions to individual telephone calls, and gradually decreases in frequency of contact. In the partner-assisted arm, partners will learn and practice communication skills and support strategies to facilitate patient health behavior change. Partners will attend patient group sessions, be informed of patients' goals (during initiation) and relapse plans (during maintenance), and receive reinforcing text messages. In months 19-24, intervention will be withdrawn to examine sustainability of effects. Our primary hypothesis is that average 24-month weight in the partner-assisted intervention will be at least 2.5 kg lower than in the patient-only intervention. Secondary outcomes include caloric intake and physical activity at 24 months. Mediation analyses will examine the role of interdependence theory constructs and social support. If successful, this approach could inform refinement and implementation of effective obesity treatments.

抽象的肥胖是美国可预防死亡的第二大原因。减肥，改善心血管疾病危险因素、身体机能和生活质量。结合饮食改变、增加体力活动和行为策略的干预措施是有效的对于短期减肥，但对于长期减肥来说则不太如此，因为这是长期减肥的最佳预测指标。减肥是初始减肥，需要策略来增强初始减肥和减肥效果饮食和身体活动行为常常受到家庭伴侣的影响。对患者及其伴侣进行联合干预可能会提高体重管理的效果这项综合研究涉及对家庭伴侣支持在权重中的作用的评估。减重启动和维持计划的资格标准包括年龄 18-75 岁、BMI ≥27 kg/m2 且患有肥胖症。相关合并症或BMI≥30 kg/m2，并且与家庭伴侣同居的夫妇将是230对。随机分配至单独针对患者或其伴侣的为期 18 个月的综合体重计划。在第 1-6 个月内，所有患者都将接受基于小组的减肥计划，其中包括限制热量饮食和在第 7 至 18 个月内，所有患者都将接受减重维持干预，其中包括体力活动。维护特定内容，过渡为单独电话通话，并逐渐减少频率在合作伙伴协助的部门中，合作伙伴将学习和练习沟通技巧和支持。促进患者健康行为改变的策略合作伙伴将参加患者小组会议并了解情况。患者的目标（开始期间）和复发计划（维持期间），并收到强化文本在 19-24 月份，我们将撤回干预措施，以检查我们的主要影响的可持续性。假设在伴侣辅助干预下 24 个月的平均体重将至少降低 2.5 公斤次要结果包括 24 岁时的热量摄入和体力活动。中介分析将检验相互依赖理论结构和社会支持的作用。如果成功的话，这种方法可以为有效肥胖治疗的完善和实施提供信息。

项目成果

期刊论文数量（3）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

A Method to Deliver Automated and Tailored Intervention Content: 24-month Clinical Trial.

DOI：
10.2196/38262
发表时间：
2022-09-06
期刊：
JMIR FORMATIVE RESEARCH
影响因子：
2.2
作者：
Miller, Hailey N.;Voils, Corrine, I;Cronin, Kate A.;Jeanes, Elizabeth;Hawley, Jeffrey;Porter, Laura S.;Adler, Rachel R.;Sharp, Whitney;Pabich, Samantha;Gavin, Kara L.;Lewis, Megan A.;Johnson, Heather M.;Yancy, William S., Jr.;Gray, Kristen E.;Shaw, Ryan J.
通讯作者：
Shaw, Ryan J.

Primary outcomes from Partner2Lose: A randomized controlled trial to evaluate partner involvement on long-term weight loss.

Partner2Lose 的主要结果：一项评估伴侣参与长期减肥的随机对照试验。

DOI：
10.21203/rs.3.rs-4001003/v1
发表时间：
2024
期刊：
Research square
影响因子：
0
作者：
Voils,Corrine;Shaw,Ryan;Gavin,Kara;Hetzel,Scott;Lewis,Megan;Pabich,Samantha;Johnson,Heather;Elwert,Felix;Mao,Lu;Gray,Kristen;Yuroff,Alice;Garza,Katya;Yancy,William;Porter,Laura
通讯作者：
Porter,Laura