Developing an adjunctive mobile application for co-morbid substance use and anxiety disorders: comprehensive user experience testing of the Unwinding Anxiety application

开发针对共病药物使用和焦虑症的辅助移动应用程序：Unwinding Anxiety 应用程序的综合用户体验测试

• 批准号: 10385945
• 负责人: William Nardi
• 金额: $ 4.68万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10385945
• 关键词: Address; Adult; Affect; Anxiety; Anxiety Disorders; Applications Grants; Caring; Clinical; Collection; Comprehensive Health Care; Custom; Data; Development; Distress; Eating Disorders; Emotional; Evidence based intervention; Evidence based treatment; Focus Groups; Funding; Future; Generalized Anxiety Disorder; Health; Health Technology; Individual; Integrative Therapy; Interview; Learning Module; Measures; Mental Health; Mobile Health Application; National Institute of Drug Abuse; Outcome; Participant; Pathway interactions; Patient-Focused Outcomes; Patients; Persons; Pharmacotherapy; Postdoctoral Fellow; Preparation; Psychotherapy; Quality of life; Recovery; Recovery Support; Reporting; Research; Research Design; Research Methodology; Resources; Role; Sampling; System; Testing; Therapeutic; Training; United States National Institutes of Health; Work; anxiety treatment; base; behavioral health; comorbidity; craving; design; digital; digital health; digital treatment; effectiveness testing; evidence base; experience; follow-up; health care settings; improved; informant; mHealth; mental health organization; mobile application; new technology; novel; patient oriented; polysubstance use; programs; psychoeducational; relapse risk; smoking cessation; social stigma; substance use; substance use treatment; treatment of anxiety disorders; treatment program; treatment strategy; usability; virtual

PROJECT SUMMARY Patients with comorbid substance use (SUD) and anxiety disorders (AD) have significantly poorer health outcomes than patients with SUD alone and experience increased risk for relapse. However, less than 10% engage in treatment and only 18% of SUD facilities and 9% of mental health organizations report the capacity to provide comprehensive care. Mobile health technologies have been increasingly applied for substance use and anxiety treatments in an effort to create more comprehensive, patient centered approaches to care. Despite increasing mobile application development, the majority of existing programs are designed to target SUD or anxiety individually, few utilize evidence-based content or are clinically validated, and the majority are not designed as integrative treatment components for patients with SUD-AD. The Unwinding Anxiety (UA) mobile app can fulfill this need as it delivers digital, evidence-based psychoeducational training in a manualized, scalable, and high-fidelity manner targeting mechanistic pathways consistent with previous research. The proposed research will comprehensively assess the user experiences of UA for individuals with SUD-AD who are in recovery and explore the role of exploratory behavioral and mental health outcomes (i.e., substance use, craving, anxiety) among 48 individuals in long term recovery (>6 months). We will utilize a convergent parallel mixed methods research study design involving the collection of both quantitative and qualitative measures concurrently. We will quantitatively investigate usability, feasibility, and fidelity using the Systems Usability Scale, educational module completion, and ecological check-in usage. Qualitatively we will collect data on usability of UA within a sub-sample of participants (n=18) conducting focused interviews weekly (4 x <30 min. sessions; n=18) and 3 focus groups (k=3; n=15). Our secondary aim is to determine the degree to which UA engages exploratory outcomes specifically substance use, craving, and anxiety in preparation for future trials. Completion of this study will result in: (1) comprehensive range of customizations grounded in patients lived experience which will be used to refine one of the first mobile applications for patients with SUD-AD serving as a scalable, evidence-based adjunctive therapy; (2) provide preliminary data for a post-doctoral NIH grant application testing this customized mobile application to improve adjunctive therapies for SUD-AD treatment.

项目摘要 合并药物使用（SUD）和焦虑症（AD）的患者的健康状况明显较差 结果比单独使用SUD和经历的患者增加了复发的风险。但是，不到10％ 从事治疗，只有18％的SUD设施和9％的精神卫生组织报告了能力 提供综合护理。移动健康技术已越来越多地用于吸毒和 焦虑治疗以创建更全面，以患者为中心的护理方法。尽管 增加移动应用程序开发，大多数现有程序旨在针对SUD或 焦虑单独使用，很少使用循证内容或经过临床验证，大多数不是 设计为SUD-AD患者的综合治疗成分。放松的焦虑（UA）手机 应用程序可以满足这种需求，因为它在手动，手动，基于证据的心理教育培训中提供了数字性的心理教育培训 靶向机械途径与先前研究一致的可扩展性和高保真方式。这 拟议的研究将全面评估UA的用户体验 正在恢复并探索探索性行为和心理健康成果的作用（即药物使用， 长期康复（> 6个月）的48个人中的渴望，焦虑）。我们将利用收敛的平行 混合方法研究设计设计涉及定量和定性措施的收集 同时。我们将使用系统可用性量表进行定量调查可用性，可行性和保真度， 教育模块的完成和生态签入使用。定性地我们将收集有关可用性的数据 UA在参与者的子样本中（n = 18）每周进行集中访谈（4 x <30分钟。会议； n = 18）和3个焦点组（k = 3; n = 15）。我们的次要目的是确定UA参与的程度 探索性结果特别是为将来的试验做准备，渴望和焦虑。完成 这项研究将导致：（1）以患者生活经验为基础的全面自定义范围 它将用于完善用于SUD-AD患者的最早的移动应用程序之一，可作为可扩展的， 基于证据的辅助治疗； （2）提供博士后NIH赠款申请测试的初步数据 该定制的移动应用程序可改善用于SUD-AD治疗的辅助疗法。