Cancer Prevention and Control

癌症预防与控制

基本信息

批准号：
10379991
负责人：
Tara Olive Henderson
金额：
$ 4.5万
依托单位：
UNIVERSITY OF CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-09-01 至 2024-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10379991
关键词：
Address Area Behavioral Behavioral Genetics Bioinformatics Biological Biological Sciences Biostatistics Core Breast Carcinoma Cancer Center Support Grant Cancer Control Cancer Patient Cancer Survivor Cancer Survivorship Catchment Area Chicago Clinic Clinical Collaborations Communities Comprehensive Cancer Center Core Facility Development Diagnosis Direct Costs Discipline Disease Economic Factors Economics Enrollment Environmental Epidemiology Epidemiology Etiology Evaluation Faculty Faculty Recruitment Fostering Funding Genetic Goals Group Meetings Hematologic Neoplasms Home Illinois Infrastructure Institution Interdisciplinary Study Intervention Knowledge Large Intestine Carcinoma Leadership Malignant Neoplasms Malignant neoplasm of prostate Medicine Mentorship Midwestern United States NCI Center for Cancer Research Outcome PMI cohort Paper Peer Review Pilot Projects Play Population Research Population Sciences Postdoctoral Fellow Prevention Prevention Research Prognosis Prostate Lymphoma Psychosocial Influences Public Health Practice Publishing Research Research Personnel Resource Sharing Resources Risk Role Schools Scientist Screening for cancer Secure Shapes Smoking Social Sciences Students Training Translating United States National Institutes of Health Universities Work anticancer research biobehavior cancer clinical trial cancer health disparity cancer prevention cancer risk career cohort community engagement design epidemiology study genetic epidemiology global health health disparity human tissue improved outcome member multi-ethnic next generation novel population based population health precision medicine programs psychologic recruit screening surveillance study survivorship symposium tissue resource working group

项目摘要

ABSTRACT The overall goal of the Cancer Prevention and Control (CPC) Program of the University of Chicago Medicine Comprehensive Cancer Center (UCCCC) is to promote novel cancer population science discoveries through interdisciplinary research focused on the themes of Cancer Risk and Prevention, and Outcomes and Survivorship, and to translate the knowledge into clinical and public health practice. This goal will be accomplished by the following Specific Aims: 1) To apply population research approaches to identify the biological, environmental and behavioral factors that contribute to cancer risk, thereby augmenting the prevention and early detection of cancer; 2) To improve outcomes and survivorship for cancer patients by identifying important economic and psychosocial issues, and designing and implementing interventions that address these issues; 3) To foster transdisciplinary interactions by organizing programmatic and thematic Working Group meetings, supporting Pilot Projects and shaping UCCCC Shared Resources, and leveraging other institutional research resources; 4) To assess the needs of our catchment area to inform the conduct of research and interventions relevant to these needs; and 5) To facilitate and coordinate training and mentorship of students at all levels, fellows, and junior faculty to grow the next generation of cancer population health scientists. The CPC Program, with 38 members from 11 Departments and two Divisions (Divisions of Biological Sciences and Social Sciences), is the home to the majority of epidemiological and cancer control and prevention research for the UCCCC. Program members, whose work can be categorized into Scientific Themes of Cancer Risk and Prevention, and Outcomes and Survivorship, are leading initiatives in UCCCC strategic areas, such as local and global health disparities, genetic epidemiology, survivorship, and cancer economics, and fostering population research across UCCCC Research Programs. In the current funding period (2013-2016), Program members published 510 cancer-focused papers (20% intraprogrammatic, 26% interprogrammatic, and 64% interinstitutional). In 2016, our Program members were supported by $4.8 million (direct costs) in peer-reviewed funding, including $1.22 million from the NCI, and $2.6 million in other NIH support, as well as $3.08 million (direct costs) in non-peer-reviewed funding. Importantly, the Program provides evaluation and dissemination of cancer control activities through collaborative efforts in our local community in collaboration with the UCCCC’s Office of Community Engagement and Cancer Disparities (OCECD), as reducing or eliminating cancer disparities is an overarching goal and cross-cutting theme across all of these activities. With support from UCCCC, CPC members established the Chicago Multiethnic Prevention and Surveillance Study (COMPASS) – the first population-based urban multiethnic cohort in the US Midwest - and led efforts to secure the NIH-funded Illinois Precision Medicine Consortium. Together, these initiatives will have lasting impact on enhancing the cancer population research portfolio at the institution for years to come.

抽象的芝加哥大学医学的预防与控制（CPC）计划的总体目标综合癌症中心（UCCCC）是通过跨学科研究重点介绍了癌症风险和预防，结果和结果的主题生存，并将知识转化为临床和公共卫生实践。这个目标将是通过以下具体目的完成：1）应用人群研究方法来识别导致癌症风险的生物，环境和行为因素，从而增加预防和早期发现癌症； 2）通过确定重要的经济和社会心理问题，并设计和实施干预措施解决这些问题； 3）通过组织程序和主题来促进跨学科互动工作组会议，支持试点项目并塑造UCCCC共享资源，并利用其他机构研究资源； 4）评估我们集水区的需求，以告知行为与这些需求相关的研究和干预措施； 5）促进和协调培训和心态各级学生，研究员和初级教师的下一代癌症人口健康科学家。 CPC计划，来自11个部门和两个部门的38名成员（生物学部门科学和社会科学），是大多数流行病学和癌症控制和 UCCCC的预防研究。计划成员，他们的工作可以分为科学癌症风险和预防的主题以及结果和生存，是UCCCC的领导倡议战略领域，例如地方和全球健康差异，遗传流行病学，生存和癌症经济学，并促进UCCCC研究计划的人口研究。在当前的资金中期间（2013-2016），计划成员发表了510篇以癌症为中心的论文（20％的术中20％，26％解释性分解和64％的机构）。 2016年，我们的计划成员得到480万美元的支持（直接费用）在同行评审的资金中，包括来自NCI的122万美元，其他NIH的260万美元支持，以及未经审查的资金的308万美元（直接费用）。重要的是，该计划提供通过我们当地社区的合作努力评估和传播癌症控制活动的活动与UCCCC社区参与与癌症差异办公室（OCECD）合作，减少或消除癌症差异是所有这些的总体目标和横切主题活动。在UCCCC的支持下，CPC成员建立了芝加哥多民族预防和监视研究（Compass） - 美国中西部的第一个基于人群的城市多民族队列 - 领导了确保NIH资助的伊利诺伊州精密医学财团的努力。这些举措在一起将有持久的影响对增强该机构的癌症人口研究组合的持续影响多年。