Research Training in Late-Life NeuroPsychiatric Disorders

晚年神经精神疾病研究培训

• 批准号: 10380616
• 负责人: Patrick J Brown
• 金额: $ 31.94万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10380616
• 关键词: Elderly; Research Training; neuropsychiatric disorder

Project Summary This submission is for continued support (years 21-26) of the T32 “Research Training in Late- life Neuropsychiatric Disorders”. The primary goal of this proposal is to train postdoctoral (MD, MD/PhD, and PhD) fellows for careers as independent researchers in Late-Life Neuropsychiatric Disorders. At the last competitive review in Nov 2013 the reviewers concluded that, “The program, now in its fifteenth year, has many important strengths including a well-structured curriculum, the range of expertise and qualifications of the faculty, effective leadership and the wealth of resources accessible to trainees through the affiliated departments and programs. The program has a clear and compelling rationale for its focus on late life, both in terms of clinical problems unique to the elderly and methodological and conceptual challenges in conducting research with this age group. However, the program's most compelling strength is the successful record of its graduates as measured by productivity, academic advancement, research funding, and contributions to science. In particular, the program has had a particularly high representation of physician scientists.” The success of the training program is reflected in both the accomplishments of the trainees and the diversity of the fellows. In the past 15 years, 28 fellows received support from the T32; 46% female, 25% MDs, 14% MD/PhDs and 61% PhDs. 11% of the fellows are under-represented minorities, and 36% come from cultural or ethnic backgrounds that are either not Caucasian or not from North America or Europe. The graduation rate is 94% (22/23 – the 1 drop-out, later came back to research at Columbia and received a K award). Of the 5 fellows not yet graduated, 4 fellows are in training (1 third fellow will graduate on 6/30/18, 1 a second-year fellow, and 2 first year fellows) and one fellow will begin training on 7/1/18. Of the 23 fellows who have graduated in the last 15 years, 35% have received K awards and of 6 fellows who finished their K 50% have received an R award. Three fellows who did not receive a K received a NARSAD. Thus 48% of graduates have received independent funding. 65% of graduates are in research-intensive positions and 9% in research- related positions. In the past 20 years all fellowship positions have been filled with very qualified candidates. A new research plan for the Department of Psychiatry created the Brain Aging and Mental Health initiative. There are two divisions in this initiative; the Division of Geriatric Psychiatry headed by Dr. Devanand (mentor) focuses on studies mild cognitive impairment, and Alzheimer's disease. The division of Neurobiology and Therapeutics of Aging, headed by Dr. Bret Rutherford (Director of Curriculum) focuses on the interplay between aging-associated processes and late-life psychiatric disorders. There are also changes in the T32 including 1) six new mentors that strengthen the basic science and translational faculty, 2) revision in the statistics and research design classes 3) addition of the fellow's monthly seminar and CNS talks 3) additions to the Responsible Conduct of Research curriculum.

项目摘要此提交是为了继续支持T32的持续支持（21 - 26年）。 生命神经精神疾病”。该提案的主要目标是培训博士后（MD，MD/PhD和 博士学位）研究人员作为晚年神经精神疾病的独立研究人员的职业研究员。最后 竞争评论在2013年11月，评论家得出结论，“该计划已有15年了 重要的优势，包括结构良好的课程，教师的专业知识和资格范围， 有效的领导力和通过会员部门培训可访问的大量资源 程序。该计划在临床方面都对后期生活有着明确而令人信服的理由 在进行研究时，旧，方法论和概念性挑战所独有的问题 年龄段。但是，该计划最引人注目的力量是其毕业生的成功记录 通过生产力，学术进步，研究资金以及对科学的贡献来衡量。尤其， 该计划对物理科学家的代表特别高。” 培训计划的成功反映在培训的成就和 研究员的多样性。在过去的15年中，28名研究员得到了T32的支持； 46％的女性，25％MD， 14％MD/PHD和61％的PHD。 11％的研究员的代表人数不足，而36％来自 不是来自北美或欧洲的高加索人的文化或种族背景。这 毕业率为94％（22/23 - 1个辍学率，后来回到哥伦比亚的研究并接受了K 奖）。在尚未毕业的5名研究员中，有4名研究员正在接受培训（三名研究员将于6/30/18，1 A毕业 二年级研究员和2个第一年的研究员）和一名研究员将于7/1/18开始训练。在23位同伴中 在过去的15年中毕业了，有35％的人获得了K奖和6个完成K 50％的研究员 已获得R奖。未收到K的三名研究员收到了Narsad。那48％的毕业生 已经获得了独立资金。有65％的毕业生处于研究密集型职位，研究中有9％ 相关职位。在过去的20年中，所有奖学金职位都充满了非常合格的候选人。 精神病学系的新研究计划创建了大脑衰老和心理健康计划。 这项倡议有两个部门；由Devanand博士（导师）领导的老年精神病学系 专注于研究轻度认知障碍和阿尔茨海默氏病。神经生物学和 由布雷特·卢瑟福（Bret Rutherford）博士（课程主任）领导的老化治疗学专注于相互作用 在衰老相关的过程和晚期精神疾病之间。 T32也有变化 包括1）加强基础科学和翻译学院的六位新导师，2）修订 统计和研究设计类3）同伴每月开创和中枢神经系统的添加3） 负责任的研究课程。