Establishment of the Bat Resource Center for the Study of Zoonotic Diseases

建立人畜共患疾病研究蝙蝠资源中心

• 批准号: 10374306
• 负责人: Gregory David Ebel
• 金额: $ 674.85万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-20 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10374306
• 关键词: Animal Model; COVID-19 pandemic; Chiroptera; Colorado; Disease; Laboratories; Modeling; Resources; Universities; Vector-transmitted infectious disease; Viral Pathogenesis; Virus Diseases; Zoonoses; design; disease transmission; human pathogen

Project Summary This proposal outlines request to establish the Bat Resource Center for the Study of Zoonotic Diseases at Colorado State University. The Bat Resource Center is a $7.99M facility located adjacent to the Center for Vectorborne Disease and the Rocky Mountain Regional Biocontainment Laboratory. It is uniquely designed to be a vivarium with the necessary environmental and biosafety controls to successfully breed and maintain bats for use as animal models. This important animal model is critical to our understanding of viral pathogenesis and disease transmission as bats have been shown to be a reservoir for a number of human pathogens including the recent COVID-19 pandemic. The Bat Resource Center will greatly enhance our abilities to study these agents and will serve as a national resource for others using bat models.

项目摘要 该提案概述了建立蝙蝠资源中心的人畜共患病资源中心的请求 科罗拉多州立大学。 BAT资源中心是一个售价799万美元的设施，位于该中心附近 用于vectorborne疾病和落基山地区生物植物实验室。它是独特的 设计为具有必要的环境和生物安全控制的Vivarium，以成功繁殖 并维护蝙蝠作为动物模型。这个重要的动物模型对于我们的理解至关重要 病毒发病机理和疾病传播作为蝙蝠已被证明是许多多个的储层 人类病原体，包括最近的Covid-19大流行。蝙蝠资源中心将大大 增强我们研究这些代理商的能力，并将作为其他人使用BAT的国家资源 型号。