06 Cancer Control and Population Sciences Program

06 癌症控制与人口科学项目

基本信息

批准号：
10362800
负责人：
Elizabeth E Brown
金额：
$ 3.52万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-03-28 至 2022-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10362800
关键词：
Address Affect African American Alabama Appalachian Region Appointment Area Arizona Behavior Therapy Behavioral Sciences Body Weight California Cancer Burden Cancer Control Cancer Survivor Cancer Survivorship Catchment Area Centers for Disease Control and Prevention (U.S.)Characteristics Clinical Sciences Collaborations Colorado Colorectal Cancer Communities Comprehensive Cancer Center Consumption Country Death Rate Deep South Early Diagnosis Early treatment Effectiveness Environmental Risk Factor Epidemiology Faculty Florida Formulation Funding General Population Genomics Goals Grant Health Health Services Accessibility Historically Black Colleges and Universities Incidence Infrastructure Integration Host Factors Intervention Intervention Studies Journals Laboratories Location Louisiana Malignant Neoplasms Malignant neoplasm of esophagus Malignant neoplasm of ovary Malignant neoplasm of pancreas Malignant neoplasm of prostate Manuscripts Medicine Mississippi Molecular Epidemiology Morehouse School of Medicine NCI-Designated Cancer Center Neoplasms Obesity Observational Study Outcome Overweight Paper Physical activity Population Population Sciences Poverty Prevalence Primary Prevention Program Development Publications Publishing Quality of life Race Research Research Personnel Research Project Grants Research Training Risk Reduction Schools Science Scientist Secondary Prevention Social Class Stretching Training Translational Research United States Universities Washington Work anticancer research base bench to bedside cancer health disparity cancer risk cancer therapy community based participatory research education resources end of life care energy balance fruits and vegetables genetic epidemiology health disparity high risk population improved inter-institutional malignant breast neoplasm member mortality multidisciplinary nutrition population based programs tertiary prevention training opportunity tumor progression

项目摘要

06 CANCER CONTROL AND POPULATION SCIENCES (CCPS) PROGRAM ABSTRACT The overall scientific goal of the CCPS Program is to reduce the burden of cancer through hypothesis-driven observational (epidemiological) and interventional translational research that spans the laboratory bench to the bedside and ultimately, the community at large (i.e., “bench to trench”). This goal guides the research of 41 highly productive scientists who are members of this Program – research that is supported by over $15 million in grant funding. Given UAB CCC's location in the Deep South, a region marked by poverty and large constituencies of underserved African-Americans and Appalachian Whites, an overarching theme of our program is to eliminate health disparities across the cancer continuum, from primary cancer risk to improved cancer survivorship. Additionally, since Alabama is a state with one of the highest rates of obesity, and that many of the most prevalent cancers within our catchment area are associated with overweight and obesity, we have worked diligently to develop a research focus in energy balance and cancer. The CCPS program is comprised of a cadre of multidisciplinary investigators who hold faculty appointments in 14 departments and 6 schools and who have broad expertise in areas of molecular and genetic epidemiology, health and cancer outcomes, cancer health disparities, behavioral science, nutrition and obesity, quality of life and end-of-life care, and cancer survivorship research. Long-term partnerships with Historically Black Colleges/Universities in our region, i.e., Morehouse School of Medicine and Tuskegee University provide a collaborative academic network that stretches across the Deep South and has resulted in research and training opportunities that are independently funded and have yielded publications in top-tier journals. The CCPS Program provides an organizational infrastructure that facilitates training for new and junior members, and active forums for collaborative interaction among all of its members. The CCPS also creates an active interface that enhances the integration of laboratory and clinical sciences, with population-based and behavioral science research. During this funding cycle, we have published 361 manuscripts of which 25% were intra-programmatic, 18% inter-programmatic, and 68% inter-institutional. Importantly, many papers and grant-funded research resulted from collaborations with investigators at other NCI-designated cancer centers, such as Fred Hutchinson, MD Anderson, Memorial Sloan Kettering, Moffitt, Mayo, Washington University in St. Louis, Dana-Farber and the Universities of Arizona, California, and Colorado.

06 癌症控制和人口科学 (CCPS) 计划抽象的 CCPS 计划的总体科学目标是通过假设驱动来减轻癌症负担观察（流行病学）和介入转化研究，跨越实验室台到这一目标指导着 41 的研究。该计划成员的高产科学家——研究经费超过 1500 万美元鉴于 UAB CCC 位于南部腹地，这是一个以贫困和面积大为特征的地区。服务不足的非裔美国人和阿巴拉契亚白人的选区，这是我们的首要主题该计划旨在消除整个癌症连续体中的健康差异，从原发性癌症风险到改善的癌症风险此外，由于阿拉巴马州是肥胖率最高的州之一，而且我们学区内许多最流行的癌症都与超重和肥胖有关，我们 CCPS 项目致力于发展能量平衡和癌症方面的研究重点。由多学科研究人员组成，他们在 14 个系和 6 个部门担任教职学校以及在分子和遗传流行病学、健康和癌症领域拥有广泛专业知识的人结果、癌症健康差异、行为科学、营养和肥胖、生活质量和临终护理和癌症生存研究与历史悠久的黑人学院/大学的长期合作关系。我们的地区，即莫尔豪斯医学院和塔斯基吉大学提供了合作学术网络遍布南方腹地，并带来了研究和培训机会 CCPS 计划提供独立资助并在顶级期刊上发表论文。促进新成员和初级成员培训的组织基础设施，以及活跃的论坛 CCPS 还创建了一个增强其所有成员之间协作互动的活跃界面。实验室和临床科学与基于人群和行为科学研究的整合。在此资助周期内，我们发表了 361 篇手稿，其中 25% 是项目内的，18% 是重要的是，产生了许多论文和资助的研究。来自与其他 NCI 指定癌症中心的研究人员的合作，例如医学博士 Fred Hutchinson 安德森、纪念斯隆·凯特琳、莫菲特、梅奥、圣路易斯华盛顿大学、丹娜法伯和亚利桑那大学、加利福尼亚大学和科罗拉多大学。