Core D: Research Experience and Training Coordination Core

核心 D：研究经验和培训协调核心

• 批准号: 10351939
• 负责人: JOHN M ESSIGMANN
• 金额: $ 6.35万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10351939
• 关键词: Animal Model; Award; Awareness; Biomedical Research; Carcinogens; Chemicals; Chloramines; Communities; Data; Data Analyses; Dependence; Development; Devices; Educational workshop; Engineering; Ensure; Environmental Engineering technology; Environmental Health; Environmental Science; Ethics; Evaluation; Exposure to; Family; Fellowship; Filtration; Fostering; Foundations; Gender; Goals; Hazardous Chemicals; Health; Human; Influentials; Interdisciplinary Study; Laboratories; Lead; Learning; Mainstreaming; Measures; Mentors; Mentorship; Methods; Mission; Municipalities; Mutagens; N-nitrosodimethylamine; Nitrosamines; Nitroso Compounds; Personal Satisfaction; Persons; Policies; Postdoctoral Fellow; Problem Solving; Public Health; Race; Research; Research Personnel; Research Project Grants; Research Support; Research Training; Risk; Rotation; STEM career; Science; Social Responsibility; Students; Superfund; System; Time; Training; Translational Research; Translations; Tribes; Water; Work; career; career development; community engagement; data management; diversity and inclusion; drinking water; experience; graduate student; implicit bias; innovation; meetings; member; next generation; programs; recruit; responsible research conduct; sensor; superfund chemical; superfund site; supportive environment; training opportunity; undergraduate research experience; underrepresented minority student; water treatment

PROJECT SUMMARY/ABSTRACT – RESEARCH EXPERIENCE AND TRAINING COORDINATION CORE N-Nitrosamines are a family of chemicals that include some of the most potent mutagens known. N-Nitrosamines are a major concern for people who live near the Olin Chemical Superfund Site, and they are also a concern of the Passamaquoddy Tribe, because the water treatment methods used for their drinking water are known to lead to formation of N-nitrosamines. The mission of the Research Experience and Training Coordination Core (RETCC) is to recruit, train, and engage the best and the brightest students for careers in Biomedical Research (BMR) and Environmental Science and Engineering (ESE) with a focus on public health. With support from the RETCC, trainees will participate in all of the proposed research, engagement, and translation activities, and they will contribute data to and benefit from the Data Management and Analysis Core (DMAC). As such, trainees fuel the entire MIT SRP program. By fostering and enabling interactions among trainees and between trainees and leaders, the RETCC supports an innovative Systems Approach of inter-dependencies among subsystems (Projects and Cores). Via a Systems Approach, all trainees impact and are impacted by all of the Projects and Cores via a network of connections that are fostered by the Administrative Core and the DMAC. Data generated by trainees will be managed by the Data Management and Analysis Core and will be integrated with data from other parts of the program to contribute to risk evaluation. Innovative aspects of the RETCC include cross- disciplinary research opportunities, training in how research can be leveraged to impact policy, and a new “MIT SRP Exploration Program” that enables trainees to spend time in other MIT laboratories. In addition, there will be several approaches to support pipeline development so as to increase the number of top students with diverse backgrounds and expertise pursuing careers in environmental health sciences and engineering. This work will include creating an MIT undergraduate research opportunity that focuses on SRP research, a new “Public Health Democratization” Pipeline Project to connect URM SRP Trainees with younger URM students. Specific Aim 1 is to provide opportunities to trainees for research, translation, community engagement, and data analysis that will help protect human health from hazardous chemicals. Specific Aim 2 is to strengthen and create programs to promote professional development. Specific Aim 3 is to recruit and promote diverse students and postdocs. Specific Aim 4 is to provide formal training to ensure that MIT SRP trainees have successful and responsible careers in biomedical research and environmental science and engineering. The Administrative Core will foster opportunities for trainees to participate in research translation, which includes interactions with stakeholders. Furthermore, the Community Engagement Core (CEC) will open doors for trainees to work with community members, including helping to deploy sensors and a filtration device that will destroy N-nitrosamines. Taken together, the RETCC provides the foundation upon which trainees thrive and enables the collective impact of the entire program.

项目概要/摘要——研究经验和培训协调核心 N-亚硝胺是一类化学物质，其中包括一些已知最有效的诱变剂。 是奥林化学超级基金基地附近居民的主要担忧，也是 帕萨马科迪部落，因为他们的饮用水使用的水处理方法已知会导致铅 研究经验和培训协调核心的使命 (RETCC) 旨在招募、培训和吸引最优秀、最聪明的学生从事生物医学研究职业 （BMR）和环境科学与工程（ESE），重点关注公共卫生。 RETCC，学员将参加所有拟议的研究、参与和翻译活动，并且他们 将为数据管理和分析核心 (DMAC) 贡献数据并从中受益。因此，学员可以为数据管理和分析核心 (DMAC) 提供动力。 整个麻省理工学院的 SRP 计划通过促进和促进受训者之间以及受训者与受训者之间的互动。 领导者，RETCC 支持子系统之间相互依赖的创新系统方法 （项目和核心）通过系统方法，所有学员都会影响所有项目和核心，并受到所有项目和核心的影响。 核心通过由管理核心和 DMAC 生成的数据培育的连接网络。 学员的数据将由数据管理和分析核心进行管理，并将与来自 该计划有助于风险评估的其他部分包括跨领域。 学科研究机会、如何利用研究影响政策的培训以及新的“麻省理工学院 SRP探索计划”，使学员能够在麻省理工学院的其他实验室度过时光。 采取多种方式支持人才梯队建设，以增加具有不同背景的尖子生数量 从事环境健康科学和工程职业的背景和专业知识。 包括创建一个麻省理工学院本科生研究机会，专注于 SRP 研究，这是一项新的“公共卫生 民主化”管道项目将 URM SRP 学员与年轻的 URM 学生联系起来。具体目标 1。 是为学员提供研究、翻译、社区参与和数据的机会 有助于保护人类健康免受危险化学品侵害的分析。 具体目标 2 是加强。 制定促进专业发展的计划 具体目标 3 是招聘和晋升。 具体目标 4 是提供正式培训以确保 MIT SRP。 学员在生物医学研究和环境科学领域拥有成功且负责任的职业生涯 行政核心将为学员提供参与研究的机会。 翻译，其中包括与利益相关者的互动此外，社区参与核心（CEC）。 将为学员与社区成员合作打开大门，包括帮助部署传感器和过滤 RETCC 为学员提供了销毁 N-亚硝胺的装置。 蓬勃发展并实现整个计划的集体影响。