Core D: Research Experience and Training Coordination Core

核心 D：研究经验和培训协调核心

• 批准号: 10351939
• 负责人: JOHN M ESSIGMANN
• 金额: $ 6.35万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10351939
• 关键词: Animal Model; Award; Awareness; Biomedical Research; Carcinogens; Chemicals; Chloramines; Communities; Data; Data Analyses; Dependence; Development; Devices; Educational workshop; Engineering; Ensure; Environmental Engineering technology; Environmental Health; Environmental Science; Ethics; Evaluation; Exposure to; Family; Fellowship; Filtration; Fostering; Foundations; Gender; Goals; Hazardous Chemicals; Health; Human; Influentials; Interdisciplinary Study; Laboratories; Lead; Learning; Mainstreaming; Measures; Mentors; Mentorship; Methods; Mission; Municipalities; Mutagens; N-nitrosodimethylamine; Nitrosamines; Nitroso Compounds; Personal Satisfaction; Persons; Policies; Postdoctoral Fellow; Problem Solving; Public Health; Race; Research; Research Personnel; Research Project Grants; Research Support; Research Training; Risk; Rotation; STEM career; Science; Social Responsibility; Students; Superfund; System; Time; Training; Translational Research; Translations; Tribes; Water; Work; career; career development; community engagement; data management; diversity and inclusion; drinking water; experience; graduate student; implicit bias; innovation; meetings; member; next generation; programs; recruit; responsible research conduct; sensor; superfund chemical; superfund site; supportive environment; training opportunity; undergraduate research experience; underrepresented minority student; water treatment

PROJECT SUMMARY/ABSTRACT – RESEARCH EXPERIENCE AND TRAINING COORDINATION CORE N-Nitrosamines are a family of chemicals that include some of the most potent mutagens known. N-Nitrosamines are a major concern for people who live near the Olin Chemical Superfund Site, and they are also a concern of the Passamaquoddy Tribe, because the water treatment methods used for their drinking water are known to lead to formation of N-nitrosamines. The mission of the Research Experience and Training Coordination Core (RETCC) is to recruit, train, and engage the best and the brightest students for careers in Biomedical Research (BMR) and Environmental Science and Engineering (ESE) with a focus on public health. With support from the RETCC, trainees will participate in all of the proposed research, engagement, and translation activities, and they will contribute data to and benefit from the Data Management and Analysis Core (DMAC). As such, trainees fuel the entire MIT SRP program. By fostering and enabling interactions among trainees and between trainees and leaders, the RETCC supports an innovative Systems Approach of inter-dependencies among subsystems (Projects and Cores). Via a Systems Approach, all trainees impact and are impacted by all of the Projects and Cores via a network of connections that are fostered by the Administrative Core and the DMAC. Data generated by trainees will be managed by the Data Management and Analysis Core and will be integrated with data from other parts of the program to contribute to risk evaluation. Innovative aspects of the RETCC include cross- disciplinary research opportunities, training in how research can be leveraged to impact policy, and a new “MIT SRP Exploration Program” that enables trainees to spend time in other MIT laboratories. In addition, there will be several approaches to support pipeline development so as to increase the number of top students with diverse backgrounds and expertise pursuing careers in environmental health sciences and engineering. This work will include creating an MIT undergraduate research opportunity that focuses on SRP research, a new “Public Health Democratization” Pipeline Project to connect URM SRP Trainees with younger URM students. Specific Aim 1 is to provide opportunities to trainees for research, translation, community engagement, and data analysis that will help protect human health from hazardous chemicals. Specific Aim 2 is to strengthen and create programs to promote professional development. Specific Aim 3 is to recruit and promote diverse students and postdocs. Specific Aim 4 is to provide formal training to ensure that MIT SRP trainees have successful and responsible careers in biomedical research and environmental science and engineering. The Administrative Core will foster opportunities for trainees to participate in research translation, which includes interactions with stakeholders. Furthermore, the Community Engagement Core (CEC) will open doors for trainees to work with community members, including helping to deploy sensors and a filtration device that will destroy N-nitrosamines. Taken together, the RETCC provides the foundation upon which trainees thrive and enables the collective impact of the entire program.

项目摘要/摘要 - 研究经验和培训协调核心 N-亚硝基胺是一个化学物质家族，其中包括一些已知的最有效的诱变剂。 N-硝基胺 对于住在Olin Chemical Superfund网站附近的人们来说，这是一个主要问题，他们也是 Passamaquoddy部落，因为已知用于饮用水的水处理方法 N-亚硝基胺的形式。研究经验和培训协调核心的任务 （RETCC）将招募，训练和吸引最优秀的和最聪明的学生从事生物医学研究的职业 （BMR）和环境科学与工程（ESE），重点是公共卫生。在 RETCC，学员将参加所有拟议的研究，参与和翻译活动，他们将参加 将为数据管理和分析核心（DMAC）贡献数据并受益。因此，实习生燃料 整个MIT SRP程序。通过促进和启用受训者之间以及学员之间的互动 领导者，RETCC支持子系统之间相互依存的创新系统方法 （项目和核心）。通过系统方法，所有受训者的影响，并受到所有项目的影响 通过管理核心和DMAC促进的连接网络的核心。生成的数据 受训人员将由数据管理和分析核心管理，并将与 该计划的其他部分有助于风险评估。 RETCC的创新方面包括交叉 纪律研究机会，如何利用研究来影响政策的培训以及新的“麻省理工学院 SRP探索计划”，使学员能够在其他麻省理工学院实验室中度过时光。此外， 是支持管道开发的几种方法，以增加潜水员的顶尖学生的数量 背景和专业知识从事环境健康科学与工程领域的职业。这项工作将 包括创建MIT本科研究机会，该研究机会专注于SRP研究，这是一种新的“公共卫生” 民主化的管道项目将URM SRP受训者与年轻的URM学生联系起来。特定目标1 是为研究，翻译，社区参与和数据提供机会 分析将有助于保护人类健康免受危险化学物质的侵害。特定目标2是加强 并创建计划以促进专业发展。特定目标3是招募和促进 多样化的学生和博士后。特定目标4是提供正规培训，以确保MIT SRP 学员在生物医学研究和环境科学领域都有成功和负责任的职业 和工程。行政核心将为受训者提供研究的机会 翻译，包括与利益相关者的互动。此外，社区参与核心（CEC） 将为受训人员打开大门与社区成员合作，包括帮助部署传感器和过滤 将破坏N-亚硝基胺的设备。综上所述，RETCC为受训者提供了基础 蓬勃发展并实现整个计划的集体影响。