Revolutionising colonoscopy - New Product Introduction of a painless magnetic endoscope

革命性结肠镜检查——无痛磁性内窥镜新产品介绍

• 批准号: 10053423
• 金额: $ 222.47万
• 依托单位: ATLAS ENDOSCOPY LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10053423
• 关键词: Revolutionising; colonoscopy; New; Product; Introduction

Early detection and treatment are crucial to improve patient quality-of-life and survival from colorectal diseases. These include cancer (which accounts for more than 881000 deaths annually worldwide) and inflammatory bowel diseases (which affect millions of individuals and increase risk of colorectal cancer). Standard colonoscopy, performed using a flexible endoscope, is currently the best method to identify disease and perform minor surgical interventions. Unfortunately, it comes with notable drawbacks: pain for the patient, long training required for operators and high costs from the technology, staffing & dedicated infrastructure. This has several impacts, the most serious being limited procedure accessibility that is resulting in uncurbed demand for colonoscopy and enormous disease and economic burden. This manifests in different ways; in the UK, an estimated 25% of patients wait more than 4 weeks to have their colonoscopy and more than 1 in 10 individuals are not attending colonoscopies even if tested positive by at-home tests. This is exacerbated by recent US Preventive Services Task Force guidelines recommending screening colonoscopy to begin at 45 instead of 50 years of age, increasing the potential screening population to 44 million individuals, in the US alone. Atlas Endoscopy aims at revolutionising colonoscopy by introducing the "REN" platform - a magnetic colonoscopy system composed of a robot and recyclable single-use endoscope.Our mission is to save lives by making colonoscopy more accessible to the population. We will do this by improving on the drawbacks of conventional flexible endoscopes. After 15 years of academic research, more than 30 peer reviewed papers (including Nature and Science), extensive pre-clinical testing and the creation of a spin-off, Atlas Endoscopy is ready to transform that research into a product, creating the technology required to deploy REN effectively and safely in hospitals for the benefit of patients, clinicians and the wider healthcare system. This grant funding will be essential to increase the technology maturity of REN, preparing the system for safe clinical use and making Atlas Endoscopy even more attractive to investors, stakeholders and the wider UK economy. Atlas Endoscopy is committed to grow the business in the UK, create jobs, attract international investment and generate significant revenue.

早期发现和治疗对于改善结肠直肠疾病的生活质量和生存至关重要。其中包括癌症（每年在全球每年有881000多人死亡）和炎症性肠病（会影响数百万个人并增加结直肠癌的风险）。使用柔性内窥镜进行的标准结肠镜检查是识别疾病并进行次要手术干预措施的最佳方法。不幸的是，它带来了显着的缺点：患者的疼痛，经营者所需的长期培训以及技术，人员配备和专用基础设施的高昂成本。这有几种影响，最严重的是有限的程序可访问性，导致对结肠镜检查和巨大疾病和经济负担的需求不受干扰。这以不同的方式表现出来。在英国，估计有25％的患者等待4周以上进行结肠镜检查，即使通过在家测试呈阳性测试阳性，也没有参加十分之一的人参加结肠镜检查。最近，美国预防服务工作队指南建议筛查结肠镜检查的时间为45岁，而不是50岁，仅在美国就将潜在的筛查人口增加到4400万个人。 ATLAS内窥镜检查旨在通过引入“ REN”平台来彻底改变结肠镜检查 - 由机器人和可回收的单使用内窥镜组成的磁性结肠镜检查系统。我们的任务是通过使人群更容易获得结肠镜来挽救生命。我们将通过改善常规柔性内窥镜的缺点来做到这一点。经过15年的学术研究，超过30份同行评审的论文（包括自然和科学），广泛的临床前测试和衍生产品的创建，Atlas内窥镜准备将其研究转化为产品，创造了在医院中有效，安全地部署REN的技术，以使患者，临床医生和广阔的医疗保健系统受益。这笔赠款对于提高REN的技术成熟至关重要，为安全临床使用准备系统，并使Atlas内窥镜检查对投资者，利益相关者和更广泛的英国经济更具吸引力。 Atlas内窥镜检查致力于在英国发展业务，创造就业机会，吸引国际投资并产生可观的收入。