Biobehavioral Effects of Inhibitory Control on Eating and Diet Behaviors Among Adolescents

抑制控制对青少年饮食和饮食行为的生物行为影响

基本信息

批准号：
10337276
负责人：
Tyler Mason
金额：
$ 14.72万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-05-01 至 2025-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10337276
关键词：
Adaptive Behaviors Address Adolescence Adolescent Adolescent obesity Adult Affect Area Base of the Brain Behavior Behavioral Binge Eating Body mass index Brain Cellular Phone Child Chronic Disease Clinical Cognition Cognitive Data Decision Making Development Diet Dietary intake Early Intervention Eating Eating Behavior Ecological momentary assessment Failure Food Foundations Functional Magnetic Resonance Imaging Goals Habits Health Health behavior Healthy Eating Hour Image Individual Differences Intake Interdisciplinary Study Interruption K-Series Research Career Programs Knowledge Laboratories Life Link Literature Longevity Maps Measures Methodology Methods Neurobiology Neurosciences Obesity Overweight Palate Parents Pathway interactions Patient Self-Report Pattern Persons Prevention Prevention Research Prevention program Process Public Health Quality of life Research Research Design Research Personnel Research Project Grants Risk Sampling Social Environment Stress Time Training Translating Unhealthy Diet base biobehavior blood oxygen level dependent career cognitive control contextual factors critical developmental period dietary food consumption fruits and vegetables health care service utilization healthy weight high body mass index modifiable behavior mortality negative affect neuroimaging obesity prevention obesity treatment peer preventive intervention programs relating to nervous system response saturated fat sugar theories

项目摘要

1 PROJECT SUMMARY/ABSTRACT 2 This K01 career development award application proposes training and research designed to provide the 3 candidate with the foundation to establish a successful career as an independent investigator with expertise in 4 biobehavioral mechanisms underlying development and progression of obesity across the lifespan. The 5 candidate proposes training to provide new expertise and knowledge in three areas including (1) child and 6 adolescent obesity prevention research; (2) foundations and assessment of diet and obesity; and (3) theory 7 and methods of neuroscience and neuroimaging. Using this training, a research project will be conducted in 8 order to apply training. The current application proposes to use a biobehavioral, multi-method approach 9 integrating neuroimaging and ecological momentary assessment (EMA) in a sample of adolescents to study 10 how inhibitory control and contextual factors influence eating and dietary intake behaviors during adolescence, 11 which is a critical transitional developmental period. Limitations of previous research on inhibitory control and 12 obesity includes (1) failure to examine within-person (momentary) associations between inhibitory control and 13 eating and dietary intake behaviors; (2) primarily studying inhibitory control and its effect on eating and dietary 14 intake behaviors in the laboratory; (3) lack of understanding of how neurobiological underpinnings of IC 15 contribute to real-time eating and dietary intake behaviors; (4) failure to study how contextual factors moderate 16 the link between inhibitory control and eating and dietary intake behaviors; and (5) lack of research on 17 adolescence. This proposed approach using neuroimaging and EMA will allow for the elucidation of: brain- 18 based pathways that underlie deficits in inhibitory control, and how these brain-based pathways map onto real- 19 world eating and dietary intake behaviors; how within-person fluctuations in inhibitory control are associated 20 with eating and dietary intake behaviors over the course of the day; and how dynamic contextual factors (e.g., 21 affect, social environment, and availability of highly palatable foods), modify the association between inhibitory 22 control and eating and dietary intake behaviors. This research will launch the candidate’s independent 23 research program focused on elucidating within- and between-person biobehavioral mechanisms underlying 24 the development and progression of obesity across the lifespan, which will be translated to integrated 25 prevention programs that take into account individual difference factors and contextual factors.

1 项目概要/摘要 2 本 K01 职业发展奖申请提出了培训和研究，旨在提供 3 名候选人具备作为独立调查员建立成功职业生涯的基础，并具有以下专业知识整个生命周期中肥胖发生和进展的 4 种生物行为机制。 5 项候选人提案培训，以提供三个领域的新专业知识和知识，包括 (1) 儿童和 6 青少年肥胖预防研究；（2）饮食与肥胖的基础和评估；（3）理论 7、神经科学和神经影像学方法将在本次培训中进行。 8 顺序应用训练当前应用建议使用生物行为、多方法方法。 9 将神经影像学和生态瞬时评估 (EMA) 整合到青少年样本中进行研究 10 抑制控制和背景因素如何影响青春期的饮食和膳食摄入行为， 11 这是一个关键的过渡发育时期，之前的抑制控制研究的局限性。 12 肥胖包括 (1) 未能检查抑制控制和抑制控制之间的人内（瞬时）关联。 13 饮食和饮食摄入行为；（2）主要研究抑制控制及其对饮食和饮食的影响； 14 实验室中的摄入行为；（3）缺乏对IC的神经生物学基础的了解； 15 有助于实时饮食和饮食摄入行为；(4) 未能研究背景因素如何调节； 16 抑制控制与饮食和膳食摄入行为之间的联系；以及 (5) 缺乏相关研究； 17 青春期所提出的使用神经影像学和 EMA 的方法将有助于阐明：抑制控制缺陷背后的 18 条通路，以及这些基于大脑的通路如何映射到真实的 19 世界饮食和膳食摄入行为；抑制控制的内部波动如何相关 20 一天中的饮食和饮食摄入行为以及动态背景因素（例如， 21 影响、社会环境和高度适口食物的可用性），改变抑制之间的关联 22 控制饮食和饮食摄入行为本研究将启动候选人的独立研究。 23 研究计划侧重于阐明人内和人与人之间的生物行为机制 24 肥胖在整个生命周期中的发展和进展，这将转化为综合 25 个考虑个体差异因素和背景因素的预防方案。