Biostatistics and Data Management Core

生物统计和数据管理核心

• 批准号: 10333068
• 负责人: Wei-Ting Hwang
• 金额: $ 8.13万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-16 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10333068
• 关键词: Address; Adherence; Basic Science; Biomedical Research; Biometry; Biostatistics Core; Canis familiaris; Case Report Form; Clinical; Clinical Trials; Clinical Trials Database; Collaborations; Consult; Data; Data Analyses; Data Management Resources; Goals; Graph; Malignant Neoplasms; Malignant neoplasm of lung; Malignant neoplasm of thorax; Manuscripts; Monitor; Monitoring Clinical Trials; Population; Preparation; Procedures; Quality Control; Reporting; Research; Research Design; Research Personnel; Research Project Grants; Safety; Sample Size; Services; Statistical Data Interpretation; Statistical Methods; Translational Research; Work; anticancer research; data management; data quality; data sharing; design; experience; member; molecular imaging; programs; research study

Project Summary/Abstract Core C (Biostatistics and Data Management) provides expert guidance and collaboration in the biostatistical and data management aspects of the design, conduct and analysis of translational research projects generated by this program project application. Prior to the initiation of studies, Core staff members consult with project investigators to help select designs that are efficient and adequately powered. As studies proceed, staff members review data periodically to evaluate adherence to study procedures, data quality, and adequacy of underlying statistical assumptions. When studies are finished, staff members review the data again, produce informative summary tables and graphical displays, conduct correct and efficient statistical analyses, and consult on the design of subsequent studies. The work of Core C involves close integration with the efforts of all the research projects. Core C staff members have extensive experience supporting cancer research, with strong backgrounds in basic science, translational research, clinical trials, research computing, and data management. With their many years of experience in biomedical research, they stand ready to identify and apply ideal methods for the statistical design and analysis and data management of P01 research studies. Core C offers its services to all P01 projects and cores.

项目概要/摘要 核心 C（生物统计和数据管理）提供专家指导和协作 转化设计、实施和分析的生物统计和数据管理方面 本计划项目申请产生的研究项目。在开始研究之前，核心 工作人员与项目调查人员协商，帮助选择高效且充分的设计 供电。随着研究的进行，工作人员定期审查数据以评估对研究的依从性 程序、数据质量和基本统计​​假设的充分性。当学习是 完成后，工作人员再次审查数据，制作信息丰富的汇总表和图形 显示，进行正确有效的统计分析，并为后续的设计提供咨询 研究。 Core C 的工作涉及与所有研究项目的工作紧密结合。核 C 工作人员在支持癌症研究方面拥有丰富的经验，在以下领域拥有深厚的背景： 基础科学、转化研究、临床试验、研究计算和数据管理。和 凭借他们多年的生物医学研究经验，他们随时准备识别并应用理想的 P01 研究的统计设计和分析以及数据管理的方法。核心C 为所有 P01 项目和核心提供服务。