Clinical and Translational Science Award

临床和转化科学奖

基本信息

批准号：
10320492
负责人：
BRUCE Neil CRONSTEIN
金额：
$ 853.49万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-08-18 至 2025-12-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10320492
关键词：
Acceleration Address Adopted Agreement Award Caring Catalogs Clinical Investigator Clinical Research Clinical Sciences Clinical Trials Clinical and Translational Science Awards Collaborations Communities Data Development Device or Instrument Development Discipline Drug Delivery Systems Effectiveness Electronic Health Record Ensure Environment Ethnic group Fostering Fruit Funding Good Clinical Practice Health Healthcare Systems Hospitals Informatics Infrastructure Institutes Institution Licensing Life Longevity Medical Methodology Methods Mission Modeling Multicenter Trials Municipalities National Center for Advancing Translational Sciences New York New York City Outcome Patients Phase Population Population Heterogeneity Privatization Procedures Process Provider Publications Race Recording of previous events Reproducibility Research Research Institute Research Personnel Research Support Research Training Resources Safety Schools Science Scientific Advances and Accomplishments Services Site Special Population Special Populations Research Speed Technology Training Training Programs Training Support Training and Education Translating Translational Research Translations United States United States National Library of Medicine Universities Validation Vision Workforce Development behavioral health college community organizations data management data sharing design digital drug development education resources electronic data epidemiology study evidence base health care delivery health difference health disparity high dimensionality improved innovation interest medical schools member metropolitan multidisciplinary multiple omics next generation novel patient oriented population health programs protocol violation public-private partnership racial diversity recruit skills training opportunity translational pipeline translational scientist wearable device

项目摘要

Contact PD/PI: CRONSTEIN, BRUCE Neil O. OVERALL – PROJECT SUMMARY The translation and implementation of groundbreaking biomedical discoveries requires the dynamic coordination of multi-disciplinary partnerships with diverse expertise, interests, and skills. The New York University (NYU) Clinical and Translational Science Institute (CTSI) represents an innovative public–private partnership designed to foster clinical and translational research, adopt evidence-based therapies, and apply scientific discoveries to transform the delivery of medical care and improve health. The CTSI successfully leveraged a partnership of institutions with unique and complementary strengths to translate science into better health, including: NYU, a private research university with a history of public service, substantial biomedical, behavioral, and population health expertise, and robust education and training programs; New York City Health and Hospitals (H+H), the largest municipal healthcare system in the United States; Nathan Kline Institute (NKI), a state psychiatric institute affiliated with NYU; and community organizations representing the richly diverse population of NYC. As the centralized hub that coordinates and integrates activities across these partners, our CTSI catalyzes research and facilitates access to essential core services, resources, and expertise necessary to engage in the full spectrum of clinical and translational research across our partner institutions. We provide educational and training opportunities for our diverse research workforce. Moreover, the CTSI serves as a nexus for collaboration between investigators at our partner institutions and the nationwide network of CTSA hubs. We more than doubled self-identified clinical and translational research at our hub over the past 10 years and established collaborations between NYU, the schools and colleges of NYU, and H+H to further accelerate the pace and impact of discovery, development, validation, and implementation across the full spectrum of translational research. We now propose an array of innovative and evidence-based strategies within the framework of the strategic domains enunciated by NCATS including: 1) Methods/Processes to streamline regulatory processes, improve the efficiency, quality, and reproducibility of research and increase the rate of implementation of research advances; 2) Collaboration/Engagement with communities, patients, providers, and researchers to elucidate and disseminate best practices and guiding principles of team science to improve translational research and health outcomes; 3) Informatics to provide a strong and innovative digital environment for subject recruitment, data management, analysis, discovery, and sharing as well as access to an extensive digital warehouse with data from electronic health records, epidemiologic studies, clinical trials, multi-omic analyses, and biospecimens; 4) Integration Across the Lifespan with Community and Patient Stakeholders to engage diverse NYC communities and special populations across the lifespan; and 5) Workforce Development to advance our efforts to educate, train, and cultivate the next generation of the translational research workforce. Project Summary/Abstract Page 302 Contact PD/PI: CRONSTEIN, BRUCE Neil O. OVERALL –

联系PD/PI：Cronstein，Bruce Neil O.总体 - 项目摘要开创性生物医学发现的翻译和实施需要动态协调具有潜水专业知识，兴趣和技能的多学科合作伙伴关系。纽约大学（纽约大学）临床和转化科学研究所（CTSI）代表设计创新的公共私有伙伴关系培养临床和翻译研究，采用循证疗法，并将科学发现应用于改变医疗服务并改善健康。 CTSI成功利用了具有独特和完整的优势的机构，将科学转化为更好的健康，包括：NYU，一个具有公共服务史，实质性生物医学，行为和人口的私立研究大学健康专业知识以及强大的教育和培训计划；纽约市健康与医院（H+H），美国最大的文化保健系统； Nathan Kline Institute（NKI），国家精神病学院与纽约大学的会员；社区组织代表了纽约市丰富的人口。作为集中式枢纽可以协调和整合这些合作伙伴的活动，我们的CTSI催化研究并促进获得完整的必要核心服务，资源和专业知识整个合作伙伴机构的临床和翻译研究范围。我们提供教育和为我们的潜水员研究人员培训机会。此外，CTSI是合作的联系在我们的合作伙伴机构的调查人员与全国CTSA枢纽网络之间。我们不仅仅是在过去的10年中，自识别的临床和翻译研究翻了一番，并建立了纽约大学，纽约大学学校和学院与H+H之间的合作，以进一步加速空间在整个转化方面的发现，开发，验证和实施的影响研究。现在，我们在该框架内提出了一系列创新和循证策略 NCAT阐明的战略领域，包括：1）简化监管过程的方法/过程，提高研究的效率，质量和可重复性，并提高实施率研究进展； 2）与社区，患者，提供者和研究人员的合作/参与阐明和传播最佳实践和指导团队科学的指导原则，以改善转化研究和健康结果； 3）信息学为主题提供强大而创新的数字环境招聘，数据管理，分析，发现和共享以及访问广泛的数字仓库具有来自电子健康记录，流行病学研究，临床试验，多摩变分析的数据，和生物测量； 4）整个生命周期的整合与社区和患者利益相关者参与纽约市各种各样的纽约社区和特殊人群在整个生命周期中； 5）劳动力发展促进我们努力教育，培训和培养下一代翻译的研究人员。项目摘要/摘要页面302 联系PD/PI：Cronstein，Bruce Neil O.总体 -