Proteins, Pathway, and Pathophysiology in Parkinson's Disease: a Gordon Research Conference

帕金森病的蛋白质、通路和病理生理学：戈登研究会议

• 批准号: 10320650
• 负责人: Maria de Lourdes Gamez Tansey
• 金额: $ 1.68万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-21 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10320650
• 关键词: Address; Affect; Age; Aging; American; Asia; Basic Science; Boston; Degenerative Disorder; Discipline; Disease; Environment; Ethnic Origin; Europe; Female; Functional disorder; Gender; Geographic Locations; Goals; Hour; International; Joints; Light; Neurodegenerative Disorders; North America; Parkinson Disease; Participant; Pathogenesis; Pathway interactions; Persons; Population; Postdoctoral Fellow; Process; Proteins; Research; Research Personnel; Rhode Island; Role; Scientist; Students; Therapeutic; Time; Translations; United States National Institutes of Health; Universities; Western World; Woman; Work; burden of illness; career; commune; cost; design; doctoral student; insight; interest; knowledge integration; meetings; men; next generation; posters; programs; social; success; symposium

Project Summary / Abstract Parkinson’s disease (PD) is a devastating degenerative disorder that affects about 1 million Americans alive today. With the greying of the Western World, the burden of this disease is set to rise steeply over the next 35 years. Research is beginning to shed light on common pathways and networks of pathogenesis and pathophysiology; this represents an incredibly exciting time of discovery in PD research. Critical to accelerate the pace of discovery and its translation is the integration of knowledge across disciplines. In this context, the specific aims for this meeting are Aim 1: To create an international meeting dedicated to basic research on PD. We are organizing a program dedicated exclusively to the Proteins, Pathway, and Pathophysiology in PD (P4 GRC). This PD GRS/GRC will be held June 13-18 at Bryant University, Smithfield, which is 1 hour south of Boston. Of 200 expected attendees (the GRC maximum), the NIH is being asked to help cover the registration costs for 13 early-career investigators (Ph.D. students & postdocs). Aim 2: To create a highly interactive format that engenders discussion of cutting-edge, unpublished results and meaningful dialogue. Successful GRC meetings require interaction, engagement, and lively discussion. The following features are designed to accomplish our goal: (i) a joint GRS/GRC meeting, that provides the opportunity for trainees to establish a rapport and dialog prior to the GRC (ii) mandatory attendance for the 5 days, (iii) communal dining, (iv) 2:1 ratio of talk to discussion time, (v) afternoon social time, (vi) well-attended, interactive poster sessions, and (vii) presence of major thought leaders in a non-intimidating, approachable setting. The meeting program was designed with input from a committee of 10 scientists (5/5 M/F) with diverse interests and backgrounds, representing North America, Europe, and Asia. This program is intended to provide scientists with diverse expertise an understanding of state-of-the-art research across disciplines and an appreciation of the critical questions that remain to be addressed. Aim 3: To promote participant diversity. We will actively encourage participant diversity in many domains: career stage, institutional environment, geographical location, gender, age, and ethnicity. The GRC program features females in both chair roles (2/2, 100%), 3/9 (33%) Discussion Leader slots, and overall, 18/37 (49%) speaking slots. The proposed program also has strong international representation, with 30% of speakers and Discussion Leaders from outside North America. ~ 30% of speaking slots are filled by junior investigators, and each of the 8 sessions will also have a 10-minute talk by a junior investigator chosen from the submitted poster abstracts.

项目摘要 /摘要 帕金森氏病（PD）是一种毁灭性的退化性疾病，今天影响了约100万美国人。随着西方世界的灰色，这种疾病的燃烧将在接下来的35年中升起。研究开始阐明通用途径和发病机理和病理生理的网络。这代表了PD研究中发现的令人兴奋的时刻。加速发现的步伐及其翻译至关重要的是跨学科的知识的整合。在这种情况下，这次会议的具体目标是目的1：创建致力于PD基础研究的国际会议。我们正在组织一个专门用于PD（P4 GRC）中蛋白质，途径和病理生理学的程序。该PD GRS/GRC将于6月13日至18日在波士顿以南1小时的史密斯菲尔德布莱恩大学举行。在200名预期的参与者（最大GRC）中，NIH被要求帮助支付13名早期研究员（博士学位学生和博士学位）的注册费用。目标2：创建一种高度互动的格式，以引发讨论尖端，未发表的结果和有意义的对话的讨论。成功的GRC会议需要互动，参与和生动的讨论。 The following features are designed to accomplish our goal: (i) a joint GRS/GRC meeting, that provides the opportunity for trainees to establish a rapport and dialog prior to the GRC (ii) mandatory attendance for the 5 days, (iii) communal dining, (iv) 2:1 ratio of talk to discussion time, (v) afternoon social time, (vi) well-attended, interactive poster sessions, and (vii) presence of major thought leaders in a非刺激性，平易近人的设置。会议计划的设计是由10位科学家（5/5 m/f）的委员会的意见，代表北美，欧洲和亚洲的潜水员利益和背景。该计划旨在为科学家提供多样性专家对跨学科的最新研究的了解，并欣赏待解决的关键问题。目标3：促进参与者的多样性。我们将积极鼓励参与者在许多领域中的多样性：职业阶段，机构环境，地理位置，性别，年龄和种族。 GRC计划以两位椅子角色（2/2，100％），3/9（33％）讨论领导者插槽以及总体上为18/37（49％）的女性题为女性。拟议的计划还具有强大的国际代表，有30％的发言人和北美以外的讨论领导者。 〜30％的讲话老虎机由初级调查人员填写，而8个课程中的每一个都将由初级调查员进行10分钟的演讲，从提交的海报摘要中进行选择。