Advancing the science on recovery community centers to support persons treated with medications for opioid use disorder: Administrative Supplement

推进康复社区中心的科学，以支持接受阿片类药物使用障碍药物治疗的人：行政补充

• 批准号: 10317332
• 负责人: Bettina B. Hoeppner
• 金额: $ 16.8万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-15 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10317332
• 关键词: Address; Administrative Supplement; Affective; Age; Autonomic nervous system; Behavioral Mechanisms; Biological; Boston; Capital; Cities; Clinical; Cognitive; Communities; Coping Skills; Criminal Justice; Disease; Disease remission; Elements; Environment; Evaluation; Exercise; Fees; Focus Groups; Foundations; Funding; Future; Goals; Grant; Individual; Institution; Intervention; Knowledge; Leadership; Measures; Mediator of activation protein; Monoclonal Antibody R24; Narcotics; National Institute of Drug Abuse; Nervous System Physiology; Opioid; Parents; Participant; Patients; Persons; Pharmaceutical Preparations; Physical Exercise; Physical Fitness; Physical activity; Predisposition; Program Evaluation; Psychophysiology; Public Health; Qualitative Evaluations; Quantitative Evaluations; Recovery; Recreation; Research; Research Activity; Research Infrastructure; Resources; Rest; Running; Science; Self Efficacy; Services; Severities; Social Change; Social Network; Stress; Substance Use Disorder; System; Testing; Therapeutic; United States; Yoga; addiction; base; behavior change; biobehavior; community center; comparative; cost; design; disorder later incidence prevention; experience; falls; innovation; instructor; interest; meetings; member; novel; opioid use; opioid use disorder; peer; pleasure; prescription opioid; program dissemination; programs; prospective; psychosocial; rapid growth; resilience; sex; social; stress reactivity; substance use; tool; volunteer

PROJECT SUMMARY/ABSTRACT The recently funded NIDA R24 entitled, Advancing The Science on Recovery Community Centers (RCCs) to Support Persons Treated With Medications for Opioid Use Disorder (R24 DA05198801) is an innovative project with the goal of cultivating and developing RCC research. Not included in this project, however, is a novel class of RCCs that support opioid and other substance use disorder recovery through peer-led physical activity and exercise. The goal of this supplement to R24 DA05198801 is to engage with and study a prototypical physical activity/exercise-based RCC known as The Phoenix, which provides a safe, recovery-oriented environment and a physically active community designed to attract and support individuals seeking addiction recovery. The Phoenix offers activities like CrossFit, rock-climbing, and yoga through a network of recovery-focused gyms. It has no fees, and its activities are run by peer volunteers who are themselves in addiction recovery. Its novel focus on physical activity, recreation, and integrating the biological with the psychosocial through leveraging the known positive benefits of engaging with others who have lived experience of addiction and recovery, has produced excitement in the field and garnered widespread interest from federal/state-level institutions, treatment systems, and criminal justice. Since its establishment in 2006, The Phoenix has grown rapidly to operate programming in 26 states with ~40,000 active members, and ~8,000 new members joining each year. The Phoenix has added programming in 25 new cities in 2020. Given the growing interest surrounding The Phoenix and its rapid expansion, there is a pressing need to understand its clinical and public health potential and explore moderators and mechanisms of its effects in a more systematic way. This need will be addressed in this study through the following aims that fit within the scope of the parent R24: 1) Engage Phoenix leaders in research- advancing activities promoting program evaluation and dissemination, and conduct focus groups with Phoenix members, peer instructors, and leadership to obtain greater contextual knowledge of participants’ experience with The Phoenix. 2) Conduct a comparative prospective, proof of concept, study (N=150; assessments at baseline, 1-, 3-, and 6-months) to test for improvements in substance use, psychosocial and psychophysiological functioning, relative to matched community controls, with psychophysiological assessments under resting and stress-reactivity conditions to explore changes in autonomic nervous system functioning. 3) Explore moderators of Phoenix’s effects that predict engagement, retention, and any derived benefits, as well as mediators through which Phoenix may confer benefit. Ultimately, this project will inform clinical decisions about patient referral to The Phoenix, and should Phoenix show signs of conferring benefit, create a foundation for future R01 clinical linkage trials.

项目摘要/摘要 最近资助的NIDA R24标题为“恢复社区中心（RCC）的科学” 接受阿片类药物使用障碍药物治疗的支持人员（R24 DA05198801）是一个创新的项目 旨在培养和发展RCC研究。但是，该项目不包括一个新颖的课程 通过同伴领导的体育锻炼和 锻炼。 R24 DA05198801补充的目标是参与和研究典型的物理 活动/基于运动的RCC称为凤凰，它提供了一个安全，面向恢复的环境， 一个身体活跃的社区，旨在吸引和支持寻求成瘾恢复的个人。 Phoenix通过以恢复为中心的健身房网络提供CrossFit，攀岩和瑜伽等活动。它 没有费用，其活动由同伴恢复的同伴志愿者进行。它的小说 专注于体育锻炼，娱乐和将生物学与心理社会融合在一起，通过利用 与已经有成瘾和康复经验的其他人互动的已知积极好处 在该领域产生了兴奋，并从联邦/州级机构中获得了广泛的兴趣，治疗 系统和刑事司法。自2006年成立以来，凤凰城已迅速发展起来 在26个州有约40,000名活跃成员，每年约有8,000名新成员加入的州进行编程。这 菲尼克斯（Phoenix 以及它的快速扩张，迫切需要了解其临床和公共卫生潜力并探索 主持人及其影响的机制以更系统的方式。这项研究将解决这一需求 通过以下目的，适合父母R24的范围：1）与凤凰领导者参与研究 - 推进促进计划评估和传播的活动，并与Phoenix进行焦点小组 成员，同伴讲师和领导才能获得更多关于参与者经验的上下文知识 与凤凰。 2）进行比较的前瞻性，概念证明，研究（n = 150；评估 基线，1-，3-和6个月），以测试使用物质的改善，心理生理学和心理生理学 相对于匹配的社区控制，以及在休息和 应力反应性条件以探索自主神经系统功能的变化。 3）探索主持人 Phoenix的效果可预测参与，保留和任何衍生好处，以及通过 凤凰城5月会议受益。最终，该项目将为患者转诊的临床决定提供信息 凤凰城和应该显示会议益处的迹象，为将来的R01临床奠定了基础 连锁试验。