AACR Special Conference on Colorectal Cancer

AACR 结直肠癌特别会议

• 批准号: 10318040
• 负责人: Margaret Foti
• 金额: --
• 依托单位: AMERICAN ASSOCIATION FOR CANCER RESEARCH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2021-08-02
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10318040
• 关键词: AACR; Special; Conference; Colorectal; Cancer

ABSTRACT The proposed conference, entitled “Colorectal Cancer” will be held October 21-24, 2021 in Minneapolis, Minnesota. This will be the second AACR conference focused specifically on advances in colorectal cancer held in the last 5 years. Colorectal cancers (CRC’s), are the second leading cause of cancer deaths in the United States. Unfavorable risk factors such as obesity, physical inactivity, and smoking in addition to an ageing population and dietary habits of high- income countries increases the risk of CRC. CRC incidence and mortality rates are also rising in the young-onset population, with ~12% of cases being diagnosed in individuals under age 50. Advancements in pathophysiological understanding have increased the array of treatment options for local and advanced disease leading to individual treatment plans Although current therapies have led to an overall decrease in CRC incidence and mortality, the 5-year survival rate for patients with advanced metastatic CRC stands at about 14%. CRC morbidity and mortality can be mitigated through appropriate screening and surveillance however its effectiveness is jeopardized by a several factors including the lack of accessibility and suboptimal screening compliance. These data highlight the acute need for continued research to improve diagnostic testing and treatment paradigms. With the aim of connecting basic and translational research to clinical care, the proposed conference will bring together research scientists and clinicians to discuss the latest findings in CRC research. To this end, the AACR is seeking support to expand the conference and to recruit outstanding young investigators through additional Scholar-in- Training awards. Attendance by this “next generation” of cancer scientists and caregivers will help better disseminate the rapidly growing collection of research innovations as well as ignite new collaborations. The program has been carefully designed to feature thought-provoking sessions on advances in risk factors and prevention, genomics, microbiome, immunotherapy, and other emerging therapies. Collaboration and networking will also be encouraged by incorporating multiple opportunities for thoughtful discussion and meaningful interaction between participants.

抽象的 拟议的题为“结直肠癌”的会议将于 2021 年 10 月 21 日至 24 日在 明尼苏达州明尼阿波利斯市这是第二次专门关注这一问题的 AACR 会议。 结直肠癌 (CRC) 是过去 5 年中取得的第二个进展。 肥胖等不利风险因素是美国癌症死亡的主要原因。 除了人口老龄化和高收入人群的饮食习惯外，缺乏身体活动和吸烟 收入国家的 CRC 发病率和死亡率也在上升。 年轻发病人群，约 12% 的病例在 50 岁以下的个体中被诊断出来。 病理生理学理解的进步增加了治疗选择的范围 尽管目前的治疗方法针对局部和晚期疾病导致个体化治疗计划 导致结直肠癌发病率和死亡率、5年生存率总体下降 晚期转移性结直肠癌患者的发病率和死亡率约为 14%。 可以通过适当的筛查和监测来缓解，但其有效性是 受到多种因素的危害，包括缺乏可及性和次优筛查 这些数据凸显了继续研究以改进诊断的迫切需要。 旨在将基础研究和转化研究联系起来。 临床护理，拟议的会议将汇集研究科学家和超级明星 讨论 CRC 研究的最新发现 为此，AACR 正在寻求支持以扩大规模。 会议并通过额外的学者招募优秀的年轻研究者 “下一代”癌症科学家和护理人员参加培训奖项将有所帮助。 更好地传播快速增长的研究创新成果并激发新的 该计划经过精心设计，以发人深省的会议为特色。 风险因素和预防、基因组学、微生物组、免疫疗法等方面的进展 通过纳入新兴疗法也将鼓励合作和网络。 之间进行深思熟虑的讨论和有意义的互动的多种机会。