Advancing the technology readiness level of rapid additive manufacturing microfluidic technology for personalised medicine and organ-on-a-chip applications.

提高用于个性化医疗和芯片器官应用的快速增材制造微流体技术的技术准备水平。

• 批准号: 10044406
• 金额: $ 6.31万
• 依托单位: FRONTIER SPACE TECHNOLOGIES LTD
• 依托单位国家: 英国
• 项目类别: Grant for R&D
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10044406
• 关键词: Advancing; technology; readiness; level; rapid

Frontier Space Technologies enable biomedical and pharmaceutical research in space for the benefit of life science applications on Earth.In this context, our main product is Space Lab, a miniaturized lab is capable of performing a wide variety of biomedical research activities in space. Each Space Lab is fully autonomous, remotely controlled, and approximately the size of a shoe box. It has a range of scientific hardware onboard including a 32 multi-chambered sample disc, a microscope, a microfluidics system and temperature, pressure and atmospheric composition sensors.Performing this kind of research has numerous benefits thanks to the natural habitat present in space, mainly microgravity and high radiation. This means that scientific research in the fields of personalized medicine, organ-on-a-chip, drug development, organ and tissue 3D printing, stem cell study, and protein crystallization is greatly facilitated when performed in space. The same technology can be brought down to Earth as a diagnostic tool for self-driven health care and de-centralised health careThe outcome of this research will initially benefit Earth and terrestrial applications.Within the Innovate UK project, Frontier is determined to perform a 6 months research period aimed at advancing the TRL of the hardware needed for personalised medicine and organ-on-a-chip, using a biocompatible 3D printer. In addition to this, this project will also allow Frontier to access new markets related to these field and funding.

Frontier Space Technologies 能够在太空中进行生物医学和药物研究，以造福地球上的生命科学应用。在这种情况下，我们的主要产品是太空实验室，这是一个小型实验室，能够在太空中进行各种生物医学研究活动。每个太空实验室都是完全自主的、远程控制的，并且大约有鞋盒大小。它搭载了一系列科学硬件，包括 32 个多室样品盘、显微镜、微流体系统以及温度、压力和大气成分传感器。由于太空中存在自然栖息地，进行此类研究有很多好处，主要是微重力和高辐射。这意味着个性化医疗、芯片器官、药物开发、器官和组织3D打印、干细胞研究和蛋白质结晶等领域的科学研究在太空中进行时将得到极大的便利。同样的技术可以作为自我驱动的医疗保健和分散式医疗保健的诊断工具带到地球上。这项研究的成果最初将有利于地球和陆地应用。在创新英国项目中，Frontier 决心执行 6为期数月的研究期旨在使用生物相容性 3D 打印机提高个性化医疗和芯片器官所需硬件的 TRL。除此之外，该项目还将让 Frontier 进入与这些领域和资金相关的新市场。