Structural Birth Defects Meetings 12th-14th

第 12-14 次结构性出生缺陷会议

• 批准号: 10226320
• 负责人: DANIEL H COHN
• 金额: --
• 依托单位: SOCIETY FOR DEVELOPMENTAL BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10226320
• 关键词: Accounting; Animal Model; Area; Basic Science; Biological; Cellular Structures; Centers for Disease Control and Prevention (U.S.); Child; Clinical; Clinical Research; Collaborations; Communities; Congenital Abnormality; Craniofacial Abnormalities; Craniosynostosis; Development; Diagnosis; Diaphragmatic Hernia; Disabled Persons; Disease; Elevator; Epidemiology; Etiology; Event; Family; Fostering; Foundations; Funding; Future; Genetic; Goals; Grant; Incidence; Infant Mortality; Institutes; Knowledge; Laboratory Study; Lead; Life; Limb Development; Medical; Mentors; Mission; Molecular; Molecular Diagnosis; National Institute of Child Health and Human Development; Neural Tube Defects; Oral; Patients; Physicians; Postdoctoral Fellow; Prevention; Public Health; Recording of previous events; Research; Research Personnel; Research Support; Role; Scientist; Severities; Socioeconomic Status; Speed; Strategic Planning; Structural Congenital Anomalies; Time; Training Support; Translations; Travel; Underrepresented Minority; United States; United States National Institutes of Health; Woman; career; congenital heart disorder; disorder prevention; graduate student; improved; infant death; innovation; insight; interest; meetings; member; new technology; next generation; novel strategies; peer; posters; prevent; programs; scoliosis; skeletal disorder; symposium; translational approach; working group

Cohn, DH Project Abstract Structural birth defects are the leading cause of infant mortality in the United States, accounting for about 20% of all infant deaths according to the Centers for Disease Control. As a result there is a deep and lasting impact of structural birth defects on public health, socioeconomic status, and family life. Accordingly, Theme 1 of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Strategic Plan is “Understanding the Molecular, Cellular, and Structural Basis of Development”, with the ultimate goal of reducing the incidence of structural birth defects. A better understanding of these disorders and their causes holds substantial promise for improving the lives of the tens of thousands of children born with such conditions in the U.S. each year. To further this goal, for nearly two decades scientists studying structural birth defects have met eleven times (approximately every two years) to describe progress and develop collaborations in support of this NICHD mission. This proposal will fund the 2020 Structural Birth Defects Meeting and the subsequent two conferences. The goals of these meetings are a) to share recent, primarily unpublished research results to understand the causes, diagnosis, treatment and prevention of structural birth defects; b) to foster collaborations among basic and physician scientists for future progress in structural birth defects research; c) to support training and mentoring of the next generation of structural birth defects investigators including graduate students, postdoctoral fellows, and medical residents and fellows through trainee- specific events during the conference; and d) to support involvement of women, underrepresented minorities and individuals with disabilities in structural birth defects research through involvement in the organization and conduct of the conference and through travel grants to attend the meeting. The three day conference will include oral and poster presentations by investigators funded under programs developed by NICHD and other NIH Institutes as well as presentations derived from submitted abstracts, talks by two keynote speakers on topics of broad interest to the attendees, a roundtable discussion of new directions in structural birth defects research, and five trainee- specific events to foster interactions with leaders in the field. Consequently, the 12th-14th Structural Birth Defects Meetings will extend the critical role and strong track record of the NICHD and the structural birth defects research community in essential, forward-looking research in this important area, accelerating the biological understanding of these disorders and new approaches for diagnosis and treatment for patients.

科恩，DH 项目摘要 结构性先天缺陷是美国婴儿死亡率的主要原因，会计 根据疾病控制中心，所有婴儿死亡中约有20％。结果 是结构性先天缺陷对公共卫生，社会经济地位的深刻而持久的影响， 和家庭生活。据尤尼斯·肯尼迪·什里弗国家儿童研究所称 健康与人类发展（NICHD）战略计划是“了解分子， 细胞和发展的结构基础”，其最终目的是减少事件 结构性先天缺陷。对这些疾病及其原因的更好理解 改善成千上万的孩子的生活的巨大希望 每年在美国的条件。为了进一步实现这一目标，近二十年的科学家学习 结构性先天缺陷已经满足了11次（大约每两年）来描述 进步与发展合作以支持这一NICHD任务。该建议将资助 2020年结构性先天缺陷会议和随后的两个会议。这些目标 会议是a）分享最新的，主要未发表的研究结果，以了解原因， 诊断，治疗和预防结构出生缺陷； b）促进合作 基础和物理科学家，以实现结构性出生缺陷研究的未来进展； c）支持 下一代结构性出生缺陷的培训和心理调查人员，包括 研究生，博士后研究员以及通过实习生的医疗居民和研究员 - 会议期间的特定事件； d）支持妇女的参与，代表人数不足 少数群体和结构性出生缺陷的疾病通过参与研究 在会议的组织和行为中，并通过旅行赠款参加会议。 为期三天的会议将包括根据根据 NICHD和其他NIH机构制定的计划以及从 提交的摘要，两位主题演讲者就与会者广泛感兴趣的主题的会谈， 关于结构性出生缺陷研究的新方向的圆桌讨论，以及五个学员 - 特定事件以促进与该领域的领导者相互作用。因此，第12-14章结构 出生缺陷会议将延长NICHD的关键作用和强烈的记录 结构性先天缺陷在这一重要的基本，前瞻性研究中研究社区 领域，加速对这些疾病的生物学理解和新方法 患者的诊断和治疗。