Structural Birth Defects Meetings 12th-14th

第 12-14 次结构性出生缺陷会议

• 批准号: 10226320
• 负责人: DANIEL H COHN
• 金额: --
• 依托单位: SOCIETY FOR DEVELOPMENTAL BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10226320
• 关键词: Accounting; Animal Model; Area; Basic Science; Biological; Cellular Structures; Centers for Disease Control and Prevention (U.S.); Child; Clinical; Clinical Research; Collaborations; Communities; Congenital Abnormality; Craniofacial Abnormalities; Craniosynostosis; Development; Diagnosis; Diaphragmatic Hernia; Disabled Persons; Disease; Elevator; Epidemiology; Etiology; Event; Family; Fostering; Foundations; Funding; Future; Genetic; Goals; Grant; Incidence; Infant Mortality; Institutes; Knowledge; Laboratory Study; Lead; Life; Limb Development; Medical; Mentors; Mission; Molecular; Molecular Diagnosis; National Institute of Child Health and Human Development; Neural Tube Defects; Oral; Patients; Physicians; Postdoctoral Fellow; Prevention; Public Health; Recording of previous events; Research; Research Personnel; Research Support; Role; Scientist; Severities; Socioeconomic Status; Speed; Strategic Planning; Structural Congenital Anomalies; Time; Training Support; Translations; Travel; Underrepresented Minority; United States; United States National Institutes of Health; Woman; career; congenital heart disorder; disorder prevention; graduate student; improved; infant death; innovation; insight; interest; meetings; member; new technology; next generation; novel strategies; peer; posters; prevent; programs; scoliosis; skeletal disorder; symposium; translational approach; working group

Cohn, DH Project Abstract Structural birth defects are the leading cause of infant mortality in the United States, accounting for about 20% of all infant deaths according to the Centers for Disease Control. As a result there is a deep and lasting impact of structural birth defects on public health, socioeconomic status, and family life. Accordingly, Theme 1 of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Strategic Plan is “Understanding the Molecular, Cellular, and Structural Basis of Development”, with the ultimate goal of reducing the incidence of structural birth defects. A better understanding of these disorders and their causes holds substantial promise for improving the lives of the tens of thousands of children born with such conditions in the U.S. each year. To further this goal, for nearly two decades scientists studying structural birth defects have met eleven times (approximately every two years) to describe progress and develop collaborations in support of this NICHD mission. This proposal will fund the 2020 Structural Birth Defects Meeting and the subsequent two conferences. The goals of these meetings are a) to share recent, primarily unpublished research results to understand the causes, diagnosis, treatment and prevention of structural birth defects; b) to foster collaborations among basic and physician scientists for future progress in structural birth defects research; c) to support training and mentoring of the next generation of structural birth defects investigators including graduate students, postdoctoral fellows, and medical residents and fellows through trainee- specific events during the conference; and d) to support involvement of women, underrepresented minorities and individuals with disabilities in structural birth defects research through involvement in the organization and conduct of the conference and through travel grants to attend the meeting. The three day conference will include oral and poster presentations by investigators funded under programs developed by NICHD and other NIH Institutes as well as presentations derived from submitted abstracts, talks by two keynote speakers on topics of broad interest to the attendees, a roundtable discussion of new directions in structural birth defects research, and five trainee- specific events to foster interactions with leaders in the field. Consequently, the 12th-14th Structural Birth Defects Meetings will extend the critical role and strong track record of the NICHD and the structural birth defects research community in essential, forward-looking research in this important area, accelerating the biological understanding of these disorders and new approaches for diagnosis and treatment for patients.

科恩，D.H. 项目摘要 结构性出生缺陷是美国婴儿死亡的主要原因 根据疾病控制中心的数据，大约 20% 的婴儿死亡都是由这种疾病造成的。 是结构性出生缺陷对公共卫生、社会经济地位产生深刻而持久的影响， 相应地，尤尼斯·肯尼迪·施赖弗国家儿童研究所的主题 1 健康与人类发展 (NICHD) 战略计划是“了解分子、 “发展的细胞和结构基础”，最终目标是减少发病率 更好地了解这些疾病及其原因。 改善数以万计患有此类疾病的儿童的生活的重大承诺 为了进一步实现这一目标，科学家们进行了近二十年的研究。 结构性出生缺陷已出现十一次（大约每两年）来描述 该提案将为 NICHD 的使命提供资金。 2020 年结构性出生缺陷会议及后续两次会议的目标。 会议是 a) 分享最近的、主要是未发表的研究成果，以了解原因， b) 促进结构性出生缺陷的诊断、治疗和预防； 基础科学家和医师科学家为结构性出生缺陷研究的未来进展提供支持； 培训和指导下一代结构性出生缺陷调查人员，包括 研究生、博士后研究员、住院医师和实习生研究员- 会议期间的具体活动；以及 d) 支持代表性不足的妇女参与 少数族裔和残疾人通过参与参与结构性出生缺陷研究 参与会议的组织和举行，并提供出席会议的旅费补助。 为期三天的会议将包括由研究人员进行口头和海报展示 NICHD 和其他 NIH 研究所开发的程序以及源自 提交的摘要、两位主讲人就与会者广泛感兴趣的主题进行的演讲、 结构性出生缺陷研究新方向圆桌讨论及五名学员 第 12-14 届结构性会议审查了旨在促进与该领域领导人互动的具体活动。 出生缺陷会议将扩大 NICHD 和 结构性出生缺陷研究界在这一重要领域进行必要的、前瞻性的研究 领域，加速对这些疾病的生物学理解以及治疗的新方法 为患者提供诊断和治疗。