Diagnostic markers of language impairment in bilingual adults

双语成人语言障碍的诊断标志物

• 批准号: 10216579
• 负责人: Yasmeen Faroqi Shah
• 金额: $ 22.68万
• 依托单位: UNIV OF MARYLAND, COLLEGE PARK
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-10 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10216579
• 关键词: Address; Adult; Affect; Agrammatism; Aphasia; Assessment tool; Behavior; Brain Injuries; Classification; Computers; Data; Diagnosis; Diagnostic; Differential Diagnosis; Education; Emotional; English Language; Exhibits; Future; Goals; Impairment; Investigation; Language; Language Disorders; Length; Linguistics; Measures; Non-aphasic; Outcome; Pattern; Performance; Persons; Population; Primary Progressive Aphasia; Productivity; Psychometrics; Quality of life; Rehabilitation therapy; Reporting; Research; Role; Semantics; Sensitivity and Specificity; Testing; Theoretical model; United States; Variant; accurate diagnosis; base; bilingualism; clinical investigation; computerized; density; diagnostic accuracy; diagnostic biomarker; disparity reduction; health disparity; improved; instrument; language impairment; lexical; middle age; neurological rehabilitation; service delivery; social; stem; tool; Address; Adult; Affect; Agrammatism; Aphasia; Assessment tool; Behavior; Brain Injuries; Classification; Computers; Data; Diagnosis; Diagnostic; Differential Diagnosis; Education; Emotional; English Language; Exhibits; Future; Goals; Impairment; Investigation; Language; Language Disorders; Length; Linguistics; Measures; Non-aphasic; Outcome; Pattern; Performance; Persons; Population; Primary Progressive Aphasia; Productivity; Psychometrics; Quality of life; Rehabilitation therapy; Reporting; Research; Role; Semantics; Sensitivity and Specificity; Testing; Theoretical model; United States; Variant; accurate diagnosis; base; bilingualism; clinical investigation; computerized; density; diagnostic accuracy; diagnostic biomarker; disparity reduction; health disparity; improved; instrument; language impairment; lexical; middle age; neurological rehabilitation; service delivery; social; stem; tool

DIAGNOSTIC MARKERS OF LANGUAGE IMPAIRMENT IN BILINGUAL ADULTS PROJECT SUMMARY Aphasia, which refers to language impairment following focal or degenerative brain injury, has a debilitating effect on a person’s quality of life due to its social, emotional and financial repercussions. A significant proportion of persons with aphasia are bilingual, given that nearly one-fifth of the U.S. population and over one-half of the world’s population is bilingual. The overlap in language behaviors between bilinguals of varying proficiency and persons with aphasia makes the diagnosis of bilingual aphasia particularly challenging. Yet, there are hardly any psychometrically valid diagnostic instruments to diagnose aphasia and differentiate it from the language variation seen across bilinguals. Over two-thirds of clinicians in the U.S. report being unprepared to assess bilingual adults due to unavailability of valid diagnostic tools and insufficient understanding of bilingual language disorders. The proposed research represents the first systematic psychometric investigation of clinical language measures in English for Spanish-English speaking bilingual adults across multiple language domains. The project will establish language measures, population norms and cut-off scores with a three-fold purpose: identification of aphasia, diagnosis of morphosyntactic and lexicosemantic impairments in aphasia. The outcomes of this project will improve diagnostic accuracy and therefore reduce health disparities for bilingual adults with aphasia.

双语成年人语言障碍的诊断标记 项目摘要 失语症是指局灶性或退化性脑损伤后语言障碍，具有 由于其社会，情感和财务状况，对人的生活质量的影响使人衰弱 反响。鉴于几乎 美国人口中的五分之一和世界人口的一半是双语。 在不同的熟练程度和患者的双语者之间与语言行为重叠 失语症使双语失语症的诊断特别挑战。但是，几乎没有 任何具有心理有效的诊断工具，以诊断失语症并将其与众不同 双语者看到的语言差异。美国报告中有三分之二的临床医生报告 由于没有有效的诊断工具和 对双语语言障碍的理解不足。拟议的研究代表 对英语的临床语言测量测量的首次系统心理测量调查 西班牙语英语双语成年人跨多种语言领域。该项目将 以三倍的目的建立语言测量，人口规范和截止分数： 识别失语症，形态同步的诊断和词汇障碍的诊断 失语症。该项目的结果将提高诊断准确性，从而降低 双语成年人失语症的健康差异。