Tweet4Wellness: Development and RCT of Mobile Social Support Groups for Sedentary Behavior Reduction

Tweet4Wellness：减少久坐行为的移动社交支持小组的开发和随机对照试验

• 批准号: 10210286
• 负责人: Marily Oppezzo
• 金额: $ 16.76万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-01 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10210286
• 关键词: Accelerometer; Address; Aerobic; Aerobic Exercise; Affect; American; Attention; Attenuated; Behavior; Behavior Therapy; Behavioral; Big Data; Biological Markers; Biosensor; Blood Pressure; Cardiac health; Cardiovascular Diseases; Cardiovascular system; Cause of Death; Clinical; Clinical Trials; Control Groups; Data; Data Analyses; Data Collection; Development; Emotional; Environment; Feedback; Foundations; Frequencies; Future; Goals; Guidelines; Health; Health Technology; Heart Diseases; Hour; Interruption; Intervention; K-Series Research Career Programs; Knowledge; Life Style; Manuscripts; Measures; Media Intervention; Mentors; Mentorship; Monitor; Movement; Participant; Patients; Pattern; Physical activity; Physiological; Policies; Prevention; Privatization; Proxy; Psychological Theory; Publications; Randomized; Randomized Controlled Trials; Recommendation; Research; Research Personnel; Risk Factors; Running; Scientist; Smoking; Social Interaction; Social support; Supervision; Support Groups; Techniques; Technology; Testing; Text Messaging; Time; Training; Twitter; Universities; Walking; Wireless Technology; Wrist; Writing; arm; base; behavior change; behavioral study; cardiovascular disorder prevention; cardiovascular disorder risk; cardiovascular effects; cardiovascular health; cardiovascular risk factor; career; career development; clinical trial implementation; computerized data processing; cost; design; effectiveness testing; evidence base; experience; falls; follow-up; heart disease risk; heart rate variability; improved; in vivo; individualized feedback; intervention effect; learned behavior; novel; peer support; post intervention; post-doctoral training; premature; primary outcome; psychologic; recruit; response; sedentary; sedentary lifestyle; skill acquisition; skills; social media; theories

7. Project Summary / Abstract This K01 Career Development Award will provide Dr. Marily Oppezzo with intensive, supervised training to establish an independent research scientist career focusing on cardiovascular disease prevention, more specifically on how to change people’s physical activity levels for heart health. This proposal builds on Dr. Oppezzo’s background as an experimentalist trained in psychological theories of learning and behavior change, and leverages the exceptional environment of Stanford University for advanced training. Under the mentorship of her team of experts, Dr. Oppezzo will advance the field of behavior change with a novel intervention to decrease sedentary behavior, and contribute to the findings of sedentary behavior’s effects on cardiovascular health. Prolonged sitting is an independent risk factor for cardiovascular disease. The health effects of too much sitting are physiologically distinct from those of too little aerobic exercise. There is growing evidence that heart disease risk from prolonged sedentary behavior can be mitigated by breaking up sitting hours and moving more frequently throughout the day. This K01 proposal utilizes technology to both: 1. decrease sedentary behavior and 2. track cardiovascular effects of sedentary behavior. 1. Through a randomized controlled trial, Dr. Oppezzo will test the effectiveness of a multicomponent social media-based intervention (Tweet4Wellness) on decreasing prolonged sedentary behavior by increasing walking bouts throughout the day. Within a private social media group, for 100 days, participants will be prompted with daily, theory-based behavior change strategies to elicit social support and interaction around their sedentary behavior goals. 2. Using collected data from non-invasive, wrist-worn wireless biosensors, real-world patterns of sedentary behavior will be associated with patterns of blood pressure and heart rate variability. This data will not only contribute to what is known about cardiovascular biomarkers and sedentary behavior, but also detect cardiovascular effects of changing sedentary behavior over time. Training to conduct the proposed K01 will address prior gaps in Dr. Oppezzo’s knowledge and skills needed to achieve her long term goal of being an independent scientist: 1) clinical trial implementation and biosensor “big data” processing and analysis (e.g. accelerometer, blood pressure, and heart rate variability monitoring data); 2) social media and health technology for behavioral interventions; 3) career development skills such as grantsmanship and manuscript publications. Through coursework, hands-on experience, and mentored training, Dr. Oppezzo will gain a conceptual and technical foundation to develop and test effective behavioral interventions for heart health. Results from the proposed project will directly inform an R01 application that will build on the successful features of the Tweet4Wellness intervention, refine less successful features, and run a larger, scaled clinical trial in patients with existing heart disease. In summary, this K01 will accelerate Dr. Oppezzo’s career development and support launching her as an independent behavioral scientist in cardiovascular disease prevention.

7。项目摘要 /摘要 这项K01职业发展奖将为玛丽·奥普佐（Marily Oppezzo）博士提供深入，监督的培训 建立独立的研究科学家职业，专注于预防心血管疾病，更多 特别是关于如何改变人们的体育锻炼水平以保持心脏健康。该提议建立在博士基础上。 Oppezzo的背景是一名经过学习和行为心理理论的实验主义者 变革，并利用斯坦福大学的特殊环境进行高级培训。在 Oppezzo博士由专家团队的遗产将通过小说推进行为改变领域 干预以减少久坐行为，并有助于久坐行为对 心血管健康。长时间坐着是心血管疾病的独立危险因素。健康 过多的坐姿的影响与有氧运动过于少。有增长 可以通过分解坐姿来缓解长期久坐行为的心脏病风险 几个小时，整天更频繁地移动。该K01提案利用技术两者：1。 减少久坐行为和2。跟踪久坐行为的心血管效应。 1。通过 随机对照试验，Oppezzo博士将测试基于社交媒体的多组分的有效性 干预（tweet4wellness）通过增加步行回合来减少长时间久坐行为 整天。在一个私人社交媒体小组中，持续100天，参与者将每天提示 基于理论的行为变革策略，以引起久坐的社会支持和互动 行为目标。 2。使用来自非侵入性，腕上无线无线生物传感器的收集数据，现实世界模式 久坐行为将与血压和心率变异性的模式有关。这些数据将 不仅有助于对心血管生物标志物和久坐行为的了解，还可以检测到 随着时间的流逝，久坐行为改变的心血管影响。进行拟议的K01进行培训 解决Oppezzo博士的知识和技能所需的先前差距，以实现她成为一个长期目标 独立科学家：1）临床试验实施和生物传感器“大数据”处理和分析（例如， 加速度计，血压和心率变异性监测数据）； 2）社交媒体和健康 行为干预的技术； 3）职业发展技巧，例如授予和手稿 出版物。通过课程工作，实践经验和指导的培训，Oppezzo博士将获得 为心脏健康开发和测试有效的行为干预措施的概念和技术基础。 拟议项目的结果将直接告知R01应用程序，该应用程序将基于成功 Tweet4Wellness干预的功能，优化较少成功的功能，并运行更大的规模临床 现有心脏病患者的试验。总而言之，这个K01将加速Oppezzo博士的职业生涯 发展和支持将她作为心血管疾病的独立行为科学家 预防。