Admin Core

管理核心

• 批准号: 10153841
• 负责人: Serdar E. Bulun
• 金额: $ 10.09万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10153841
• 关键词: 3-Dimensional; Address; Administrator; Advisory Committees; Affect; African American; Age-Years; Area; Biology; Caucasians; Cell Culture Techniques; Cells; Chromatin; Communication; Development; Education and Outreach; Ensure; Epigenetic Process; Feedback; Fibroid Tumor; Financial Support; Fostering; Funding; Future; Genotype; Goals; Growth; Gynecologic; HMGA2 gene; Health; Human Resources; Individual; Knowledge; Link; Medical; Methodology; Mission; National Institute of Child Health and Human Development; Pathologist; Pilot Projects; Population; Process; Progesterone; Research; Research Personnel; Research Project Grants; Resources; Running; Science; Series; Services; Somatic Mutation; Structure; Symptoms; Tissue Procurements; Tissue Sample; Tissues; Training Activity; Tumor Biology; United States National Institutes of Health; Update; Uterine Fibroids; Uterus; Woman; Work; base; cancer genome; cell preparation; cohesion; community based participatory research; community engagement; design; epigenomics; experience; genome-wide; high throughput technology; human tissue; in vivo Model; insight; meetings; novel; precision medicine; prevent; procedure cost; response; side effect; stem cell function; therapeutic target; tumor; tumorigenesis

The overall goal of the Administrative Core is to provide a robust centralized administrative structure that will coordinate the activities of the proposed NCTRI Northwestern Uterine Leiomyoma Center researchers and provide operational support that will reduce the burden on its investigators, allowing them to focus on their research. The Core will ensure that the proposed Center achieves its aims and will synergize the efforts of the Research Project investigators with the work of the Education and Outreach Core and the Tissue Procurement and Cell Culture Core. The Administrative Core will coordinate the participation of the Research Project investigators in the community engagement and research training activities of the Education and Outreach Core. We have developed an optimally organized Tissue/Cell Core, run by an experienced gynecologic pathologist to support LM research at Northwestern; this will provide an efficient facility for procuring and banking tissue samples and for cell preparation and storage. This facility is entirely supported by intramural funds from Northwestern. The Administrative Core will ensure and coordinate the distribution of human tissues and cells to all Center investigators. The Core will also solicit and coordinate a rigorous review process for Pilot Project applications. Below are the aims of the Administrative Core, which capture the overall objectives. AIM 1. Reduce administrative barriers within and between Center Research Projects by providing funds and resource management services. AIM 2. Foster team science through established communication methodologies to integrate cross-disciplinary research and coordinate scientific efforts within the Center and externally. AIM 3. Provide an administrative framework to evaluate the progress of the Research Projects and the Cores to ensure a rapid pace of high-quality research and to solicit Pilot Project applications and rigorously select the best Pilot Project. All aims will be achieved through the efforts of the Core Director, Dr. Bulun and the Research Administrator, Erin Simpson, who will provide overall and comprehensive administrative support. Aim 1 is designed to provide support for financial and human resources management for the investigators, projects and cores; the Bulun and Simpson team will serve as the liaison to NIH and to central offices at Northwestern. Aim 2 will be accomplished through a series of communication efforts, including recurring meetings for research progress and communication updates and the coordination of the Research Projects and Core functions. Aim 3 will support the efforts of the Internal and External Advisory Committees that will review each project's progress and provide feedback on the overall Center and help review the Pilot Project applications and select the best Pilot Project. By aligning the Center through these activities, the Administrative Core will ensure the uninhibited progress of the Center's research, leverage team science and cross-disciplinary efforts to accelerate the pace of discovery, and evaluate progress and trajectory so the Center is consistently on target.

行政核心的总体目标是提供强大的集中行政结构 协调拟议的NCTRI西北子宫平滑肌中心研究人员和 提供运营支持，以减轻调查人员的负担，使他们能够专注于自己的 研究。核心将确保所提议的中心实现其目标，并协同作用 研究项目调查人员在教育和外展核心以及组织采购方面的工作 和细胞培养核心。行政核心将协调研究项目的参与 社区参与和研究培训活动的研究人员的教育和外展核心活动。 我们已经开发了一个由经验丰富的妇科病理学家运行的最佳组织/细胞核心 支持西北地区的LM研究；这将为采购和银行组织提供有效的设施 样品以及用于细胞的准备和存储。该设施完全由 西北。行政核心将确保并协调人组织和细胞的分布 所有中心调查员。核心还将为试点项目征求并协调严格的审核过程 申请。以下是捕获总体目标的行政核心的目的。目标1。减少 通过提供资金和资源，中心研究项目内和之间的行政障碍 管理服务。目标2。通过既定的沟通方法来培养团队科学 整合跨学科研究并在中心内和外部协调科学工作。目标3。 提供管理框架来评估研究项目和核心的进度 快速的高质量研究速度，征求飞行员项目应用程序，并严格选择最佳飞行员 项目。所有目标将通过核心主任Bulun博士和研究的努力来实现 管理员艾琳·辛普森（Erin Simpson）将提供总体而全面的行政支持。目标1是 旨在为调查人员，项目和人力资源管理提供支持 内核； Bulun和Simpson团队将担任NIH的联络人和西北部的中央办公室。目的 2将通过一系列的沟通工作来完成，包括重复的研究会议 进度和沟通更新以及研究项目和核心功能的协调。目标3 将支持内部和外部咨询委员会的努力，这些委员会将审查每个项目的进度 并提供有关整个中心的反馈，并帮助审查试点项目申请并选择最佳 试点项目。通过通过这些活动使中心对齐，行政核心将确保不受限制 中心研究的进步，利用团队科学和跨学科的努力来加速步伐 发现，并评估进度和轨迹，因此中心一直在目标上。