Genetic Counseling (GC)

遗传咨询（GC）

• 批准号: 10152538
• 负责人: Wendy K Kohlmann
• 金额: $ 13.15万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-09 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10152538
• 关键词: Address; Adherence; Applications Grants; Area; Basic Science; Behavioral Research; Cancer Biology; Cancer Center; Cancer Center Support Grant; Catchment Area; Chemoprevention; Clinic; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Collaborations; Collection; Communication; Consultations; Data; Effectiveness; Electronic Health Record; Ensure; Ethics; Familial Adenomatous Polyposis Syndrome; Funding; Genes; Genetic; Genetic Counseling; Genetic Research; Genetic Services; Genetic Translation; Goals; Grant; Guidelines; Hereditary Malignant Neoplasm; Hereditary Neoplastic Syndromes; Image; Individual; Inherited; Institutes; Intervention; Logistics; Malignant Neoplasms; Medical Genetics; Methods; Mission; National Cancer Institute; Oncology; Outcome; Participant; Patient Care; Patient-Focused Outcomes; Patients; Peer Review; Population; Population Policies; Primary Health Care; Principal Investigator; Program Research Project Grants; Protocols documentation; Publications; Qualifying; Recording of previous events; Research; Research Design; Research Institute; Research Personnel; Resource Sharing; Resources; Risk; Risk Management; Rural Population; Sampling; Science; Scientific Advances and Accomplishments; Services; Sushi Domain; Syndrome; Translating; Translations; Utah; Work; anticancer research; cancer care; cancer genetics; cancer predisposition; cancer risk; clinical care; clinical implementation; clinical phenotype; clinically significant; cohort; design; ethical legal social implication; gene discovery; genetic analysis; genetic counselor; genetic information; genetic testing; innovation; member; novel; novel strategies; programs; recruit; screening; service intervention; tool; translational genetics

GENETIC COUNSELING SHARED RESOURCE ABSTRACT The Genetic Counseling Shared Resource (GC) facilitates basic science, clinical, and behavioral research necessary to translate genetic discoveries into clinical care. GC has provided clinical genetics services and supported genetic research at Huntsman Cancer Institute (HCI) since 2003 (supported by the Cancer Center Support Grant since 2009) and has been directed by Wendy Kohlmann, MS, CGC, since 2006. GC is quintessential to HCI’s mission and builds on HCI’s long history of gene discovery by leading practice-changing research endeavors to determine the clinical utility of genetic testing, optimal methods for risk communication and delivery of genetic counseling, and strategies to manage risk conveyed by inherited cancer predispositions. GC is integral to a major goal of the Cancer Center, bringing scientific discoveries to the clinic and into applications for the population. GC provides several key services necessary for translational genetic research, including identifying cohorts of patients for gene research or studies of syndromes; helping investigators design studies to optimally incorporate genetic information and to anticipate and address ethical, legal, and social issues related to genetic analysis; providing genetic counseling interventions; and collecting clinical phenotypes and longitudinal outcomes data. The aims of GC are 1) to provide cancer genetics expertise, genetic counseling services, and interventions, and 2) to support the scientific research objectives of the Cancer Center, especially in the context of translation of genetics to the clinic and population. Access to research genetic counseling services has allowed Cancer Center members to study novel approaches for providing genetic information and to include participants across our catchment area, the State of Utah. GC adds value to the Cancer Center by ensuring genetics expertise is available to all Cancer Center members and clinical investigators. The broad impact of GC across HCI is indicated by its contribution to 61 publications since 2014. Cancer Center members with peer-reviewed funding comprise 53% of the users, and 100% of GC’s work is cancer-related. HCI’s establishment of a top-quality, research-oriented Genetic Counseling Shared Resource is highly innovative and unique among National Cancer Institute cancer centers. The Director and staff of the Shared Resource participate in national committees, and they extend the impact of HCI research by incorporating findings into guidelines for genetic testing and management of hereditary cancer. GC allows HCI to excel in all areas of hereditary cancer research and to be a leader in genetic discoveries and translation of findings into clinical implementation and population policy.

遗传咨询共享资源 抽象的 遗传咨询共享资源（GC）促进了基础科学，临床和行为研究 将遗传发现转化为临床护理所必需的。 GC提供了临床遗传学服务和 自2003年以来，Huntsman Cancer Institute（HCI）的遗传研究（由癌症中心支持） 自2009年以来的支持赠款），由MS，CGC的Wendy Kohlmann指导。 对HCI的使命典型，并通过改变实践改变的基础HCI的悠久基因发现历史 研究努力确定基因检测的临床实用性，风险交流的最佳方法 以及遗传咨询的提供，以及管理遗传癌症传达风险的策略 倾向。 GC是癌症中心的主要目标不可或缺的一部分，将科学发现带到了诊所 并进入人口的申请。 GC提供了翻译遗传所需的几种关键服务 研究，包括确定基因研究或综合症研究的患者人群；帮助 研究人员设计研究以最佳纳入遗传信息并预测和解决道德， 法律和与遗传分析有关的社会问题；提供遗传咨询干预措施；并收集 临床表型和纵向结果数据。 GC的目的是1）提供癌症遗传学 专业知识，遗传咨询服务和干预措施以及2）支持科学研究目标 癌症中心，特别是在将遗传学转化为诊所和人群的背景下。 获得研究遗传咨询服务使癌症中心成员可以研究新颖 提供遗传信息并包括我们集水区，国家的参与者的方法 犹他州。 GC通过确保所有癌症中心都可以使用遗传学专业知识来为癌症中心增加价值 成员和临床研究人员。 GC在HCI中的广泛影响以61的贡献表明 自2014年以来的出版物。进行同行评审资金的癌症中心成员占53％的用户，以及 GC的100％与癌症有关。 HCI建立高质量的，以研究为导向的遗传咨询共享资源是高度的 国家癌症研究所癌症中心的创新性和独特性。共享的董事和工作人员 资源参与国家委员会，并通过进口来扩展HCI研究的影响 发现遗传癌基因检测和管理指南。 GC允许HCI脱颖而出 遗传性癌症研究的领域，并成为遗传发现的领导者，并将发现转化为 临床实施和人口政策。