Research on personalized medicine against treatment-resistant liver cancer from the viewpoint of epithelial-Mesenchymal Transition and hierarchical replication ability

从上皮间质转化和分级复制能力角度进行难治性肝癌个体化治疗研究

• 批准号: 15K10162
• 负责人: NAGANO Hiroaki
• 金额: $ 2.83万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K10162/
• 关键词: 肝細胞癌; 治療抵抗性; 形質転換; 癌幹細胞; 個別化治療

项目成果

肝細胞癌（HCC）に対する術後補助療法としてのHSP70-mRNA導入樹状細胞療法第I/II相試験（中間報告）

HSP70-mRNA引入的树突状细胞疗法作为肝细胞癌（HCC）术后辅助治疗的I/II期研究（中期报告）

• 发表时间: 2017
• 作者: 8.松井洋人;硲彰一;中島正夫;松隈聰;兼清信介;徳光幸生;新藤芳太郎;恒富亮一;友近忍;飯田通久;徳久善弘;坂本和彦;鈴木伸明;武田茂;吉野茂文;玉田耕治;上野富雄;永野浩昭
• 通讯作者: 永野浩昭

Clinical significance of surgical resection of metastatic lymph nodes from hepatocellular carcinoma

• DOI: 10.1007/s00595-014-1028-8
• 发表时间: 2015-09-01
• 期刊: SURGERY TODAY
• 影响因子: 2.5
• 作者: Tomimaru, Yoshito;Wada, Hiroshi;Nagano, Hiroaki
• 通讯作者: Nagano, Hiroaki

Poorly differentiated hepatocellular carcinoma accompanied by anti-Hu antibody-positive paraneoplastic peripheral neuropathy

• DOI: 10.1111/pin.12304
• 发表时间: 2015-07-01
• 期刊: PATHOLOGY INTERNATIONAL
• 影响因子: 2.2
• 作者: Matsui, Takahiro;Hori, Yumiko;Morii, Eiichi
• 通讯作者: Morii, Eiichi

Serum Mac-2 binding protein is a novel biomarker for chronic pancreatitis

• DOI: 10.3748/wjg.v22.i17.4403
• 发表时间: 2016-05-07
• 期刊: WORLD JOURNAL OF GASTROENTEROLOGY
• 影响因子: 4.3
• 作者: Maekawa, Tomohiro;Kamada, Yoshihiro;Miyoshi, Eiji
• 通讯作者: Miyoshi, Eiji

Highly sensitive stool DNA testing of Fusobacterium nucleatum as a marker for detection of colorectal tumours in a Japanese population

• DOI: 10.1177/0004563216643970
• 发表时间: 2017-01-01
• 期刊: ANNALS OF CLINICAL BIOCHEMISTRY
• 影响因子: 2.2
• 作者: Suehiro, Yutaka;Sakai, Kouhei;Yamasaki, Takahiro
• 通讯作者: Yamasaki, Takahiro