Mechanistic insight into linkage between genome replication and particle formation of hepatitis C virus

丙型肝炎病毒基因组复制与颗粒形成之间联系的机制见解

• 批准号: 18H02661
• 负责人: Suzuki Tetsuro
• 金额: $ 10.9万
• 依托单位: Hamamatsu University School of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2018
• 资助国家: 日本
• 起止时间: 2018-04-01 至 2021-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18H02661/
• 关键词: ウイルス複製; タンパク質リン酸化; 脱リン酸化酵素; C型肝炎ウイルス; ゲノム複製; 粒子形成; ウイルス

项目成果

Occludin‐binding single‐chain variable fragment and antigen‐binding fragment antibodies prevent hepatitis C virus infection

Occludin结合单链可变片段和抗原结合片段抗体可预防丙型肝炎病毒感染

• DOI: 10.1002/1873-3468.13975
• 发表时间: 2020
• 期刊: FEBS Letters
• 影响因子: 3.5
• 作者: Shimizu Yoshimi;Shinoda Takehiro;Shirasago Yoshitaka;Kondoh Masuo;Shinya Naoko;Hanada Kentaro;Yagi Kiyohito;Suzuki Tetsuro;Wakita Takaji;Kimura‐Someya Tomomi;Shirouzu Mikako;Fukasawa Masayoshi
• 通讯作者: Fukasawa Masayoshi

The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication.

• DOI: 10.1038/s41598-018-31421-6
• 发表时间: 2018-09-03
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Shirasaki T;Honda M;Yamashita T;Nio K;Shimakami T;Shimizu R;Nakasyo S;Murai K;Shirasaki N;Okada H;Sakai Y;Sato T;Suzuki T;Yoshioka K;Kaneko S
• 通讯作者: Kaneko S

USP15 Participates in Hepatitis C Virus Propagation through Regulation of Viral RNA Translation and Lipid Droplet Formation

• DOI: 10.1128/jvi.01708-18
• 发表时间: 2019-03-01
• 期刊: JOURNAL OF VIROLOGY
• 影响因子: 5.4
• 作者: Kusakabe, Shinji;Suzuki, Tatsuya;Matsuura, Yoshiharu
• 通讯作者: Matsuura, Yoshiharu

Prevalence and viral loads of polyomaviruses BKPyV, JCPyV, MCPyV, TSPyV and NJPyV and hepatitis viruses HBV, HCV and HEV in HIV-infected patients in China.

• DOI: 10.1038/s41598-020-74244-0
• 发表时间: 2020-10-13
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Zhou X;Nakashima K;Ito M;Zhang X;Sakai S;Feng C;Sun H;Chen H;Li TC;Suzuki T
• 通讯作者: Suzuki T

Thermostable hepatitis C virus JFH1-derived variant isolated by adaptation to Huh7.5.1 cells

通过适应 Huh7.5.1 细胞分离出耐热丙型肝炎病毒 JFH1 衍生变体

• DOI: 10.1099/jgv.0.001117
• 发表时间: 2018
• 期刊: Journal of General Virology
• 影响因子: 3.8
• 作者: Shirasago Yoshitaka;Fukazawa Hidesuke;Aizaki Hideki;Suzuki Tetsuro;Suzuki Takeru;Sugiyama Kazuo;Wakita Takaji;Hanada Kentaro;Abe Ryo;Fukasawa Masayoshi
• 通讯作者: Fukasawa Masayoshi