Development of improved mechanical ventilation model for recovery(Fostering Joint International Research)

开发改进的机械通气恢复模型（促进国际联合研究）

• 批准号: 15KK0131
• 负责人: Ichinoseki-Sekine Noriko
• 金额: $ 7.74万
• 依托单位: Juntendo University
• 依托单位国家: 日本
• 项目类别: Fund for the Promotion of Joint International Research (Fostering Joint International Research)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016 至 2018
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15KK0131/
• 关键词: 筋萎縮; 横隔膜; ミトコンドリア; 機械的人工換気; 硫化物

项目成果

Intermittent spontaneous breathing prevents mechanical ventilation-induced diaphragm atrophy and dysfunction

间歇性自主呼吸可预防机械通气引起的膈肌萎缩和功能障碍

• 发表时间: 2017
• 作者: Noriko Ichinoseki-Sekine;Toshinori Yoshihara;Takamasa Tsuzuki;Aaron Morton;Matthew J Hinkley;Scott K Powers;Hisashi Naito
• 通讯作者: Hisashi Naito

Mitochondrial accumulation of doxorubicin in cardiac and diaphragm muscle following exercise preconditioning.

• DOI: 10.1016/j.mito.2018.02.005
• 发表时间: 2019-03
• 期刊: Mitochondrion
• 影响因子: 4.4
• 作者: Morton AB;Mor Huertas A;Hinkley JM;Ichinoseki-Sekine N;Christou DD;Smuder AJ
• 通讯作者: Smuder AJ

Increased SOD2 in the diaphragm contributes to exercise-induced protection against ventilator-induced diaphragm dysfunction.

• DOI: 10.1016/j.redox.2018.10.005
• 发表时间: 2019-01
• 期刊: Redox biology
• 影响因子: 11.4
• 作者: Morton AB;Smuder AJ;Wiggs MP;Hall SE;Ahn B;Hinkley JM;Ichinoseki-Sekine N;Huertas AM;Ozdemir M;Yoshihara T;Wawrzyniak NR;Powers SK
• 通讯作者: Powers SK

Hydrogen sulfide prevents mechanical ventilation-induced diaphragm atrophy and dysfunction

硫化氢可预防机械通气引起的膈肌萎缩和功能障碍

• 发表时间: 2018
• 作者: Noriko Ichinoseki-Sekine;Aaron B. Morton;Ashley J. Smuder;J. Matthew Hinkley;Scott K Powers
• 通讯作者: Scott K Powers

Treadmill exercise training protects against metabolic dysfunction and diaphragm weakness in obese diabetic rats

跑步机运动训练可预防肥胖糖尿病大鼠的代谢功能障碍和膈肌无力

• 发表时间: 2018
• 作者: Noriko Ichinoseki-Sekine;Takamasa Tsuzuki;J Matthew Hinkley;Toshinori Yoshihara;Hiroyuki Kobayashi;Scott K Powers;Hisashi Naito
• 通讯作者: Hisashi Naito