Study on novel mechanism for TRPV1-mediated control of neuropathic pain

TRPV1介导的神经病理性疼痛控制新机制研究

• 批准号: 24590734
• 负责人: TAKEHIKO Maeda
• 金额: $ 3.49万
• 依托单位: Nigata University of Phermacy and Applied Life Sciences
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24590734/
• 关键词: 神経障害性疼痛; 骨髄移植; 骨髄キメラマウス; カプサイシン; TRPV1; ノックアウトマウス; 触アロディニア

项目成果

Study on Novel Mechanism Underlying Analgesia Targeting TRPV1

• DOI: 10.1248/yakushi.13-00236-1
• 发表时间: 2014-03-01
• 期刊: YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
• 影响因子: 0.3
• 作者: Maeda, Takehiko;Ozaki, Masanobu
• 通讯作者: Ozaki, Masanobu

Possible Involvement of Endogenous Opioid System Located Downstream of <i>α</i>7 Nicotinic Acetylcholine Receptor in Mice With Physical Dependence on Nicotine

尼古丁生理依赖小鼠<i>α</i>7烟碱乙酰胆碱受体下游的内源性阿片系统可能参与其中

• DOI: 10.1254/jphs.13172fp
• 发表时间: 2014
• 期刊: Journal of Pharmacological Sciences
• 影响因子: 3.5
• 作者: Ueno K1;Kiguchi N;Kobayashi Y;Saika F;Wakida N;Yamamoto C;Maeda T;Ozaki M;Kishioka S.
• 通讯作者: Kishioka S.

The critical role of spinal ceramide in the development of partial sciatic nerve ligation-induced neuropathic pain in mice

• DOI: 10.1016/j.bbrc.2012.03.153
• 发表时间: 2012-05-04
• 期刊: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
• 影响因子: 3.1
• 作者: Kobayashi, Yuka;Kiguchi, Norikazu;Kishioka, Shiroh
• 通讯作者: Kishioka, Shiroh

TRPチャネルを標的とする新規鎮痛機序の解析

针对 TRP 通道的新型镇痛机制分析

• 发表时间: 2013
• 作者: 藤野裕道;織戸貴史;中村浩之;川島辰男;村山俊彦;前田武彦
• 通讯作者: 前田武彦

Epigenetic Augmentation of the Macrophage Inflammatory Protein 2/C-X-C Chemokine Receptor Type 2 Axis through Histone H3 Acetylation in Injured Peripheral Nerves Elicits Neuropathic Pain

• DOI: 10.1124/jpet.111.187724
• 发表时间: 2012-03-01
• 期刊: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
• 影响因子: 3.5
• 作者: Kiguchi, Norikazu;Kobayashi, Yuka;Kishioka, Shiroh
• 通讯作者: Kishioka, Shiroh