Development of Three-dimensional Micro- Rapid Prototyping Technique using Highspeed Confocal Scanner and Flow Measurement of Micro- Multiphase Flow

高速共焦扫描仪三维微快速成型技术及微多相流流量测量的发展

• 批准号: 23760144
• 负责人: OISHI Masamichi
• 金额: $ 2.91万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23760144/
• 关键词: マイクロ光造形; 共焦点スキャナ; デジタルミラーデバイス; マイクロ混相流; マイクロ流

In this study, we develop a rapid prototyping technique of a complex three-dimensional shape in a microchannel that in mind for use in the model experiment for the behavior elucidation of the red blood cells. We have proposed a three-dimensional lithography using DMD (digital mirror device) in combination with high-speed confocal scanner. The optical design to eliminate the illumination non-uniformity is particularly concerned by introducing a beam homogenizer and spatial filter, and it reduces to 10% the difference in brightness over the entire region. Since the curing spot of confocal effect is tend to be thicker than the theoretical confocal depths, the possibility of thinner polymerization is indicated by decreasing the intensity of the laser and a longer exposure time.

在这项研究中，我们在微通道中开发了一种复杂的三维形状的快速原型制作技术，该技术考虑到模型实验，以阐明红细胞的行为。我们已经提出了使用DMD（数字镜设备）与高速共聚焦扫描仪结合使用的三维光刻。通过引入梁均质器和空间滤光片，尤其涉及消除照明不均匀的光学设计，并将整个区域的亮度差异降低到10％。由于共聚焦作用的固化斑点往往比理论共识深度较厚，因此通过降低激光的强度和更长的暴露时间来指示较薄的聚合的可能性。

项目成果

MEASUREMENT OF THREE DIMENSIONAL FLOW STRUCTURE DURING MICRODROPLET FORMATION USING PHASE-LOCKED MULTICOLOR CONFOCAL MICRO-PIV

使用锁相多色共焦 Micro-PIV 测量微滴形成过程中的三维流动结构

• 发表时间: 2013
• 作者: M. Oishi;H. Kinoshita;T. Fujii and M. Oshima
• 通讯作者: T. Fujii and M. Oshima

Study on the mechanism of droplet formation in T-junction microchannel

T型连接微通道液滴形成机理研究

• DOI: 10.1016/j.ces.2011.10.048
• 发表时间: 2012-02-13
• 期刊: CHEMICAL ENGINEERING SCIENCE
• 影响因子: 4.7
• 作者: Li, Xiao-Bin;Li, Feng-Chen;Oshima, Marie
• 通讯作者: Oshima, Marie

混相流断層画像を基にした液滴の3次元形状の再構築

基于多相流层析图像的 3D 液滴形状重建

• 发表时间: 2013
• 作者: Xiao-Bin Li;Feng-Chen Li;Juan-Cheng Yang;Haruyuki Kinoshita;Masamichi Oishi and Marie Oshima;松浦佑樹,大石正道,向井信彦,大島まり,張英夏
• 通讯作者: 松浦佑樹,大石正道,向井信彦,大島まり,張英夏

Visualization and Measurement of Flow-Induced Dynamic Motion of Red Blood Cells Using Tracking Confocal Micro-PIV System

使用跟踪共焦微 PIV 系统对血流引起的红细胞动态运动进行可视化和测量

• 发表时间: 2012
• 作者: M. Oshima;M. Oishi;H. Kinoshita;T. Fujii
• 通讯作者: T. Fujii

Phase-locked confocal micro-PIV measurement of three dimensional flow structure of transient droplet formation mechanism in T-shaped micro junction

锁相共焦微PIV测量T形微连接瞬态液滴形成机制的三维流动结构

• 发表时间: 2012
• 作者: M. Oishi;H. Kinoshita;T. Fujii;M. Oshima
• 通讯作者: M. Oshima