Visualization and measurement of the micro-multiphase flow with deformable particles which represent the red blood cells

代表红细胞的可变形颗粒的微多相流的可视化和测量

• 批准号: 21760121
• 负责人: OISHI Masamichi
• 金额: $ 2.91万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21760121/
• 关键词: 柔軟粒子; 血球; 混相流; マイクロPIV; マイクロ流路

We made spherical microbeads, which represent the red blood cells, by droplet formation method using microjunction. The microbeads had the diameter of 95・m and the variation coefficient of 7.8%. The refractive index matching of microbeads and surrounding fluid for PIV measurement was successfully conducted. As a result, the interaction between the rigid rotation motion of microbeads and surrounding flow was investigated quantitatively. The measurement of red blood cells was also conducted as a target for comparison. The difference of the motions between rigid sphere and red blood cell are investigated from the viewpoint of their geometry, structure and stiffness.

我们利用微连接的液滴形成方法制备了代表红细胞的球形微珠，微珠的直径为95μm，变异系数为7.8%，用于PIV测量的微珠和周围流体的折射率匹配成功。结果，定量研究了微珠的刚性旋转运动与周围流动之间的相互作用，并作为比较的目标进行了测量。从刚性球体和红细胞的几何形状、结构和刚度的角度研究它们之间的运动。

项目成果

Three-Dimensional Reconstruction of Confocal Micro-PIV Data with Phase Adjusting Technique Using Optical Proximity Sensor

利用光学接近传感器的相位调整技术对共焦微型 PIV 数据进行三维重建

• 发表时间: 2009
• 期刊: Proceedings of The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS 2009)
• 作者: M.Oishi;H.Kinoshita;T.Fujii;M.Oshima
• 通讯作者: M.Oshima

多波長共焦点マイクロPIVによるマイクロT字ジャンクションにおける液滴生成機構の解明

使用多波长共焦微型 PIV 阐明微型 T 形接头处的液滴生成机制

• 发表时间: 2009
• 期刊: 可視化情報学会論文集 Vol.29、Suppl.No.2
• 作者: 大石正道;大島まり;木下晴之;藤井輝夫;小林敏雄
• 通讯作者: 小林敏雄

Continuous Measurement of Red Blood Cells using Target Tracking Confocal Micro-PIV

使用目标跟踪共焦微型 PIV 连续测量红细胞

• 发表时间: 2010
• 作者: 大石正道;木下晴之;藤井輝夫;大島まり;M.Oishi
• 通讯作者: M.Oishi

Target Tracking Confocal Micro-PIV for Continuous Measurement of Red Blood Cells

用于连续测量红细胞的目标跟踪共焦微型 PIV

• 发表时间: 2010
• 期刊: Proceedings of The 14th International Symposium on Flow Visualization No.ISFV14-1A-4 CD-R
• 作者: M.Oishi;K.Utsubo;H.Kinoshita;T.Fujii;M.Oshima
• 通讯作者: M.Oshima

Investigation of Droplet Formation Mechanism in Micro T-shaped Junction using Confocal Micro-PIV Measurement

使用共焦微型 PIV 测量研究微型 T 形结中的液滴形成机制

• 发表时间: 2009
• 作者: M.Oishi;H.Kinoshita;T.Fujii;M.Oshima
• 通讯作者: M.Oshima