Influence of radiation dose on detection of early CT sign of acute cerebral infarction and aneurysms

放射剂量对急性脑梗死及动脉瘤早期CT征象检出的影响

• 批准号: 23591814
• 负责人: IMAI Kuniharu
• 金额: $ 3.24万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23591814/
• 关键词: 脳卒中; CT画像; 水晶体線量; 鮮鋭度; 輪郭検出能; コントラスト分解能; 単位被ばく線量当たりの情報量; 撮像条件; CT検査; 超急性期脳梗塞; 高電圧・高電流撮像法; デュアルエナジスキャン; 仮想単色CT画像; 画質評価; ビームハードニング効果; CTアンギオ検査; 動脈瘤; 脳梗塞; 逐次近似再構成画像; 適正撮像条件; 脳動脈瘤; 適正X線線量; 仮想単色X線

The purpose of this study is to propose the optimal exposure parameters in brain CT examination for stroke. We have designed two kinds of the brain phantoms and subcontracted the phantom manufacture to R-TEC Co. Ltd and Techno-rad Co.Ltd: one is composed of simulated brain parenchyma, intracranial arteries with various intracranial aneurysms, and skull bone, and the other is composed of simulated brain parenchyma with ischemic damage and complete infarction and skull bone. These head phantoms were scanned using a 64-multidetector CT scanner with various exposure parameters and use of various reconstruction techniques. These results were summarized as follows; (1) Lens dose increased with tube voltage and current. (2) The detectability of aneurysms was improved by reconstructing CT images using a model based iterative reconstruction algorism. (3) Dual energy scanning technique yielded the improvement of the detectability of the hypodensities corresponding to early ischemic brain damage.

本研究的目的是提出脑卒中脑CT检查的最佳曝光参数。我们设计了两种脑体模，并分包给R-TEC Co. Ltd和Techno-rad Co. Ltd制作：一种是由模拟脑实质、带有各种颅内动脉瘤的颅内动脉、颅骨组成，另一种是由缺血性损伤、完全梗塞的模拟脑实质和颅骨组成。使用具有各种曝光参数并使用各种重建技术的 64 多探测器 CT 扫描仪对这些头部模型进行扫描。这些结果总结如下： (1) 透镜剂量随着管电压和电流的增加而增加。 (2)通过使用基于模型的迭代重建算法重建CT图像，提高了动脉瘤的可检测性。 (3)双能扫描技术提高了早期缺血性脑损伤对应低密度的检测能力。