Role of matrix proteins on the differentiation and activity of hard tissue forming cells and calcification during tooth formation.
基质蛋白对牙齿形成过程中硬组织形成细胞的分化和活性以及钙化的作用。
基本信息
- 批准号:21592329
- 负责人:
- 金额:$ 2.91万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2009
- 资助国家:日本
- 起止时间:2009 至 2011
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This study clarified that ameloblastin, one of the enamel matrix protein, suppressed mitotic activity and raised expression of amelogenin and enamelin of the ameloblat-linage cell in vitro, and was essential for normal mitosis and differentiation of cells of Hertwig' s epithelial root sheath during root formation in vivo. Moreover, ameloblastin is supposed to be one of the candidate molecules of inducing differentiation of odontoblasts and cementocytes.
这项研究澄清说,阿素基质蛋白是牙釉质基质蛋白之一,抑制了有丝分裂活性,并在体外抑制了氨基糖蛋白和搪瓷蛋白的表达,并且在体外是阿米洛布拉特 - 林细胞的搪瓷蛋白,对于赫特维格(Hertwig)在vivo中赫特维格(Hertwig)上皮根鞘层的细胞的正常有丝分裂和分化是必不可少的。此外,氨基蛋白细胞蛋白被认为是诱导牙胶细胞和胶质细胞分化的候选分子之一。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Ameloblastin regulates osteogenicdifferentiation by inhibiting Src kinasevia cross talk between integrin beta1 andCD63.
成釉素通过整合素 beta1 和 CD63 之间的串扰抑制 Src 激酶,从而调节成骨分化。
- DOI:
- 发表时间:2011
- 期刊:
- 影响因子:5.3
- 作者:Iizuka S.;Kudo Y.;Yoshida M.;Tsunematsu T.;Yoshiko Y.;Uchida T.;Ogawa I.;Miyauchi M.;Takata T.
- 通讯作者:Takata T.
Fine structural and immunohistochemicaldetection of collar enamel in the teeth of Polypterus senegalus, an actinopterygianfish
放线鱼牙齿颈釉质的精细结构和免疫组织化学检测
- DOI:
- 发表时间:2012
- 期刊:
- 影响因子:0
- 作者:Sasagawa I.;Yokosuka H.;Ishiyama M.;Mikami M.;Shimokawa H. Uchida T.
- 通讯作者:Shimokawa H. Uchida T.
Ameloblastin regulates osteogenic differentiation by inhibiting Src kinase via cross talk between integrin beta1 and CD63.
成釉细胞通过整合素 beta1 和 CD63 之间的串扰抑制 Src 激酶,从而调节成骨分化。
- DOI:
- 发表时间:2011
- 期刊:
- 影响因子:5.3
- 作者:Iizuka S;et al.
- 通讯作者:et al.
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
UCHIDA Takashi其他文献
UCHIDA Takashi的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('UCHIDA Takashi', 18)}}的其他基金
Verbal Sightseeing Guidebook for Visualy-impaired by Combining Verbal AR Navigation App. and Sound VR System
结合言语AR导航应用程序的视障言语观光指南。
- 批准号:
19H02265 - 财政年份:2019
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Development of Teaching Materials Which Support Co-creation Through Student Dialogue and Cooperation Targeted to Resolving Socioscientific Issues
开发支持通过学生对话与合作共同创造的教材,旨在解决社会科学问题
- 批准号:
18K13172 - 财政年份:2018
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Sharing System of Guiding Robots for Visually Impaired People
视障人士导引机器人共享系统
- 批准号:
17K18911 - 财政年份:2017
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
Voice AR Pedestrian Navigation System for Visually Impaired using NFC Device and Robot Technologies
使用 NFC 设备和机器人技术为视障人士提供语音 AR 行人导航系统
- 批准号:
16H04430 - 财政年份:2016
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Feasibility study on Curators TV to extend accessibity to cultural facilities
Curators TV 扩大文化设施无障碍性的可行性研究
- 批准号:
25630218 - 财政年份:2013
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Development of synthesis, separation, and functionalization techniques of endohedral fullerenes via ion source plasmas
通过离子源等离子体开发内嵌富勒烯的合成、分离和功能化技术
- 批准号:
24710095 - 财政年份:2012
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
A System of Visually-impaired People Navigation Equipped with AR and RFID
配备AR和RFID的视障人士导航系统
- 批准号:
24360209 - 财政年份:2012
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Mobile phone based hybrid pedestrian navigation system for visually handicapped people to enhance their quality of life
基于手机的混合行人导航系统,帮助视力障碍人士提高生活质量
- 批准号:
21360247 - 财政年份:2009
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
First-principles molecular dynamics theory of magnetic structures and phase transitions in the frustrated antiferromagnetic alloys
受挫反铁磁合金磁结构和相变的第一性原理分子动力学理论
- 批准号:
19540374 - 财政年份:2007
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Molecular biological study of the function of matrix proteins in the early stage of tooth development, with special reference to cytodifferentiation and initial calcification
牙齿发育早期基质蛋白功能的分子生物学研究,特别是细胞分化和初始钙化
- 批准号:
18592002 - 财政年份:2006
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
相似海外基金
Application of multifunctional membrane using enamel protein for periodontal tissue regeneration
牙釉质蛋白多功能膜在牙周组织再生中的应用
- 批准号:
21K16986 - 财政年份:2021
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Introduction of proteolytic enzyme into biomineralization process and its application to tooth enamel regeneration
蛋白水解酶引入生物矿化过程及其在牙釉质再生中的应用
- 批准号:
19K22717 - 财政年份:2019
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
Development of a Multifunctional Membrane for Periodontal Tissue Regenerative Therapy with Two Enamel Proteins
利用两种牙釉质蛋白开发用于牙周组织再生治疗的多功能膜
- 批准号:
18K17040 - 财政年份:2018
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
MMP20による低分子量G蛋白/細胞骨格系を介するエナメル質形成機構の解明
MMP20阐明低分子量G蛋白/细胞骨架系统介导的牙釉质形成机制
- 批准号:
16H07387 - 财政年份:2016
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Research Activity Start-up
Effects of enamel matrix protein on the metabolism of periodontal tissue and application of enamel matrix protein for orthodontic treatment.
釉质基质蛋白对牙周组织代谢的影响及其在正畸治疗中的应用
- 批准号:
23792428 - 财政年份:2011
- 资助金额:
$ 2.91万 - 项目类别:
Grant-in-Aid for Young Scientists (B)