Identification of molecules associated with intravesical recurrence of non-muscle invasive bladder cancer and the development of novel therapeutic strategy based on the molecular mechanism

鉴定与非肌层浸润性膀胱癌膀胱内复发相关的分子并基于分子机制开发新的治疗策略

基本信息

  • 批准号:
    21592045
  • 负责人:
  • 金额:
    $ 2.83万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 财政年份:
    2009
  • 资助国家:
    日本
  • 起止时间:
    2009 至 2011
  • 项目状态:
    已结题

项目摘要

Through the evaluation of molecules associated with cell cycle, cell adherence and EMT, we developed predictive systems for intravesical recurrence of non-muscle invasive bladder cancer. In addition, we suggested the usefulness of novel therapeutic strategy targeting these molecules for preventing intravesical recurrence of non-muscle invasive bladder cancer.
通过评估与细胞周期,细胞依从性和EMT相关的分子,我们开发了用于非肌肉浸润性膀胱癌静脉复发的预测系统。此外,我们提出了针对这些分子来预防非肌肉浸润性膀胱癌的新型治疗策略的有用性。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Expression of integrin proteins in non-muscle invasive bladder cancer : significance of intravesical recurrence following transurethral resection
整合素蛋白在非肌层浸润性膀胱癌中的表达:经尿道切除术后膀胱内复发的意义
  • DOI:
  • 发表时间:
    2010
  • 期刊:
  • 影响因子:
    4.5
  • 作者:
    Miyake H;(他5名;2番目)
  • 通讯作者:
    2番目)
Growth inhibition and chemosensitization in human bladder cancer KoTCC-1 cells by siRNA targeting heat shock protein-70
靶向热休克蛋白70的siRNA对人膀胱癌KoTCC-1细胞的生长抑制和化疗增敏
  • DOI:
  • 发表时间:
    2010
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Hideaki Miyake;Tomoaki Terakawa;Iori Sakai;Junya Furukawa;Yuji Kusuda;Mototsugu Muramaki;Atsushi Takenaka;Masato Fujisawa
  • 通讯作者:
    Masato Fujisawa
Small interfering RNA targeting heat shock protein 70 enhances chemosensitivity in human bladder cancer cells
  • DOI:
    10.1016/j.urolonc.2011.07.007
  • 发表时间:
    2011-01-01
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Behnsawy, H. M.;Miyake, H.;Fujisawa, M.
  • 通讯作者:
    Fujisawa, M.
Expression of cell cycle-associated proteins in superficial bladder cancer : correlation with intravesical recurrence following transurethral resection
浅表性膀胱癌中细胞周期相关蛋白的表达:与经尿道切除术后膀胱内复发的相关性
  • DOI:
  • 发表时间:
    2009
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Miyake H;他5名(2番目)
  • 通讯作者:
    他5名(2番目)
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MIYAKE Hideaki其他文献

MIYAKE Hideaki的其他文献

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{{ truncateString('MIYAKE Hideaki', 18)}}的其他基金

Investigation of the molecular mechanism mediating the acquired resistance to docetaxel in castration-resistant prostate cancer and the development of the novel therapy targeting this mechanism
去势抵抗性前列腺癌多西紫杉醇获得性耐药的分子机制研究及针对该机制的新疗法的开发
  • 批准号:
    18K09164
  • 财政年份:
    2018
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Investigation of mechanism mediating resistant phenotype of renal cell carcinoma to tyrosine kinase inhibitors and development of novel therapy to ovetrcome its resistance
肾细胞癌酪氨酸激酶抑制剂耐药表型机制研究及耐药新疗法的开发
  • 批准号:
    24592389
  • 财政年份:
    2012
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Development of novel therapies based on the progression mechanism in prostate cancer involving the seminal vesicle
基于累及精囊的前列腺癌进展机制开发新疗法
  • 批准号:
    19591848
  • 财政年份:
    2007
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)

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腫瘍免疫の再活性化を可能にする悪性グリオーマ分子標的治療薬の開発
开发能够重新激活肿瘤免疫的恶性胶质瘤分子靶向治疗药物
  • 批准号:
    20K09333
  • 财政年份:
    2020
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    $ 2.83万
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    Grant-in-Aid for Scientific Research (C)
Antitumor effect of antiepileptic drugs on malignant glioma
抗癫痫药物对恶性胶质瘤的抗肿瘤作用
  • 批准号:
    19K09491
  • 财政年份:
    2019
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
The regulation of cancer recurrence by the construction of immunosurveilance targeing cell cycle withdrawal/reentry cancer cell
构建针对细胞周期退出/再入癌细胞的免疫监视调控癌症复发
  • 批准号:
    19K22662
  • 财政年份:
    2019
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Challenging Research (Exploratory)
Study of Segment Regeneration and Fibonacci-ratio development with the aid of Polynomial-life models
借助多项式寿命模型研究线段再生和斐波那契比率发展
  • 批准号:
    18K12036
  • 财政年份:
    2018
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Progressive multifocal leukoencephalopathy (PML); Analysis of anti-JC viral reaction and host immune response
进行性多灶性白质脑病 (PML);
  • 批准号:
    18K07397
  • 财政年份:
    2018
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
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