The effect of somatosensory evoked potentials on the onset of voluntary movement

体感诱发电位对随意运动起始的影响

• 批准号: 12680036
• 负责人: ARAKI Hideo
• 金额: $ 1.92万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12680036/
• 关键词: voluntary movement; SEPs; gating

The purpose of the study was to investigate the sequential changes of somatosensory evoked potentials (SEPs) accompanying voluntary movement, in comparison of self-voluntary movement and CNV-paradigm. The SEPs, Movement related cortical potentials and CNVs were recorded through the epoch preceding and accompanying movement of right thumb. Cerebral N20 and N18 were investigated according to the temporal relationship between the onset of movement and 7 epoch (500 msec) set by computer under the condition of stimulating the median nerve of right wrist. SEPs were recorded in 16 (experimental (1)) and 18 (experimental (2)) subjects and averaged in 7 successive epochs extending from 2.0 sec before onset of EMG to 0.5 sec after offset of EMG. The attenuation of both N20, i.e, gating, were clearly observed in epoch pre- and post-movement and was greatest in the epoch during movement, but that of N18 was not clear (experimental (1)). The change of N20 elicited by stimulating central nerve was different from that of N18. However, the difference between both components was not shown under the condition of stimulairig cutanuous (experimental (2)). From these findings, the gating is considered to be reflected the changes of afferent information processing at not central level but peripheral sites.

本研究的目的是通过比较自主运动和 CNV 范式，研究伴随自主运动的体感诱发电位 (SEP) 的连续变化。 SEP、运动相关皮质电位和 CNV 是在右手拇指运动之前和伴随运动期间记录的。在刺激右腕正中神经的情况下，根据计算机设定的运动开始与7个epoch（500毫秒）之间的时间关系来调查大脑N20和N18。记录 16 名（实验 (1)）和 18 名（实验 (2)）受试者的 SEP，并在从 EMG 开始前 2.0 秒到 EMG 偏移后 0.5 秒的 7 个连续时期内进行平均。 N20（即门控）的衰减在运动前后的历元中均明显观察到，并且在运动期间的历元中最大，但N18的衰减不明显（实验（1））。 N20刺激中枢神经引起的变化与N18不同。然而，在刺激皮肤的条件下，两种成分之间没有表现出差异（实验（2））。从这些发现来看，门控被认为反映的是外围部位而非中央水平的传入信息处理的变化。

项目成果

Hideo Araki: "Modulations of short latency components of SEPs accompanying voluntary movements"PERSPECTIVE AND PROFILES 6th ECSS.. 787 (2001)

Hideo Araki：“伴随随意运动的 SEP 短潜伏期成分的调节”视角和概况第 6 届 ECSS.. 787 (2001)

Hideo Araki: "Modulations of short latency components of SEPs accompanying voluntary movements"PERSPECTIVE AND PROFILES 6th ECSS. 787 (2001)

Hideo Araki：“伴随随意运动的 SEP 短延迟成分的调节”视角和概况第 6 期 ECSS。

Hideo Araki: "Modulations of short latency components of SEPs accompanying"PERSPECTIVE AND PROFILES 6th ECSS. 787 (2001)

Hideo Araki：“SEP 的短延迟组件的调制伴随”视角和概要文件第 6 期 ECSS。