Protection of infectious diseases of fish by co-cultured microbial product

共培养微生物产品对鱼类传染病的防护

• 批准号: 21580378
• 负责人: KODAMA Hiroshi
• 金额: $ 3.16万
• 依托单位: Osaka Prefecture University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21580378/
• 关键词: 穴あき病; インネートイムニティー; 感染防御; 共棲発酵微生物; サイトカイン; 粘液胞子虫性やせ病; Aeromonas salmonicida; Enteromyxum leei; やせ病; 粘液胞子虫; 共棲発酵細菌

A microbial culture was prepared by co-cultivation of Lactobacillus paracasei, Saccharomyces cereviciae and Pichia membranifaciens. Oral administration of heat-inactivated co-cultured material to common carp or tiger puffer induced effective protection against infection with atypical Aeromonas salmonicida which causes ulcer disease, and myxosporean emaciation disease of tiger puffer caused by Enteromyxum leei, respectively. These results indicate that the co-cultured material, delivered in feeds, is effective in preventing infectious diseases through activation of innate immunity in fish.

通过共培养副干酪乳杆菌、酿酒酵母和膜毕赤酵母制备微生物培养物。给鲤鱼或虎河鲀口服热灭活的共培养材料，可分别诱导对引起溃疡病的非典型杀鲑气单胞菌感染和由肠粘菌引起的虎河鲀粘孢子消瘦病的感染。这些结果表明，在饲料中提供的共培养材料可以通过激活鱼类的先天免疫来有效预防传染病。

项目成果

トラフグにおける粘液胞子虫性やせ病の病態と血液性状値解析

虎河豚粘孢子厌食症病理及血液性状分析

• 发表时间: 2011
• 作者: 大谷健太;矢賀部和也;岩崎忠;児玉洋;堀谷勇介;竹中重雄;栂瀬英夫
• 通讯作者: 栂瀬英夫

酵母・乳酸菌混合培養物による非特異免疫応答増強

酵母/乳酸菌混合培养增强非特异性免疫反应

• 发表时间: 2010
• 作者: 児玉祥;加島実;中村秀顕;岩崎忠;栂瀬英夫
• 通讯作者: 栂瀬英夫

Protection against atypical Aeromonas salmonicida infection in common carpby oral administration of a mixed microbial culture of Lactobacillus paracasei, Pithia membranifaciens and Saccharomyces cereviciae.

口服副干酪乳杆菌、膜腐病菌和酿酒酵母的混合微生物培养物，可预防鲤鱼的非典型杀鲑气单胞菌感染。

• 发表时间: 2011
• 期刊: J. Vet. Med. Sci.
• 作者: Kodama;H.;Nakamura;H.;Kashima;M.;Iwasaki;T. and Togase;H.
• 通讯作者: H.

トラフグの粘液胞子虫性やせ病の病態と,酵母・乳酸菌共棲発酵培養物による予防

河豚粘孢子厌食病的病理及酵母菌与乳酸菌共存发酵培养的防治

• 发表时间: 2011
• 期刊: MPアグロジャーナル
• 作者: 堀田こずえ;高桑弘樹;村瀬敏之;小野悦郎;伊藤壽啓;大槻公一;山城哲;堀田こずえ;児玉洋
• 通讯作者: 児玉洋

Protection against atypical Aeromonas salmonicida infection in common carp by oral administration of a mixed microbial culture of Lactobacillus paracasei, Pichia membranifaciens and Saccharomyces cereviciae

通过口服副干酪乳杆菌、膜毕赤酵母和酿酒酵母的混合微生物培养物来预防鲤鱼的非典型杀鲑气单胞菌感染

• 发表时间: 2011
• 期刊: Journal of Veterinary Medical Science
• 影响因子: 1.2
• 作者: Kodama;H.;et al
• 通讯作者: et al