Detailed estimation of local circuit structure based on spike time reliability of cortical neurons

基于皮层神经元尖峰时间可靠性的局部电路结构的详细估计

• 批准号: 20700304
• 负责人: TERAMAE Junnosuke
• 金额: $ 2.25万
• 依托单位: The Institute of Physical and Chemical Research
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20700304/
• 关键词: リミットサイクル; 確率過程; ノイズ; スパイク; 発火率; 対数正規分布; ネットワーク; 理論神経科学; 計算論的神経科学; 大脳皮質; 揺らぎ; 非線形振動子; 確率微分方程式; 情報表現; 同期; 位相; temoral coding

Isolated cortical neurons have known to respond to fluctuating inputs with high temporal precision about few milliseconds. The reliable responses of neurons, however, may be influenced local network structure in cortex. Here, we provided theories which clarify relationship between response reliability of neurons and potential factors including network structure, intrinsic properties of neurons, EPSP (excitatory-postsynaptic potentiation) distribution, and statistics of input signals. We have also reveals possible generation mechanism of fluctuating input to cortical neurons and computational role of them.

已知的孤立皮质神经元对较高的时间精度的波动输入作出反应，大约很少毫秒。但是，神经元的可靠反应可能会影响皮质中的局部网络结构。在这里，我们提供了理论，可以阐明神经元的响应可靠性与潜在因素之间的关系，包括网络结构，神经元的固有特性，EPSP（兴奋性poStsynaptic增强）分布和输入信号的统计数据。我们还揭示了向皮质神经元转移的可能产生机制以及它们的计算作用。

项目成果

裾野の広いEPSP分布は大脳皮質のUP状態、低頻度非同期発火、精緻な発火時系列を一括して説明する

宽尾 EPSP 分布共同解释了大脑皮层的 UP 状态、低频异步放电以及复杂的放电时间序列。

• 发表时间: 2010
• 作者: 寺前順之介;深井朋樹
• 通讯作者: 深井朋樹

Reliability of response spike timings in pulse-coupled networks of neurons

神经元脉冲耦合网络中响应尖峰时序的可靠性

• 发表时间: 2009
• 作者: 寺前順之介;深井朋樹;寺前順之介;坪泰宏;Kang S;坪泰宏;坪泰宏;中江健;深井朋樹;Isomura Y;深井朋樹;深井朋樹;寺前順之介
• 通讯作者: 寺前順之介

Long-tailed EPSP distribution accounts for low-rate asynchronous firings, the up-state, and precise firing sequences in cortical networks

长尾 EPSP 分布解释了皮质网络中的低速率异步放电、上状态和精确放电序列

• 发表时间: 2010
• 作者: Jun-nosuke Teramae;Tomoki Fukai;Jun-nosuke Teramae;寺前順之介;Jun-nosuke Teramae
• 通讯作者: Jun-nosuke Teramae

Spike timing and possible roles of noise in cortical computation

尖峰时序和噪声在皮层计算中的可能作用

• 发表时间: 2010
• 作者: Jun-nosuke Teramae;Tomoki Fukai;Jun-nosuke Teramae;Jun-nosuke Teramae;Jun-nosuke Teramae
• 通讯作者: Jun-nosuke Teramae

Noise-induced synchronization of coupled oscillators and precision of spike coding in the brain

噪声引起的耦合振荡器同步和大脑尖峰编码的精度

• 发表时间: 2008
• 作者: 寺前順之介;深井朋樹;Atsuhiko Yoshida;Jun-nosuke Teramae
• 通讯作者: Jun-nosuke Teramae