Relation of apex-to-base dispersion in diastolic lengthening to left ventricular diastolic function evaluated by tissue tracking system

组织追踪系统评估舒张期延长的心尖底离散度与左心室舒张功能的关系

• 批准号: 20500420
• 负责人: MURATA Kazuya
• 金额: $ 3.08万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20500420/
• 关键词: 超音波医学; 心不全; 医用システム; 生理学; 解析学; 肥大型心筋症

METHODS : We obtained basal and apical LV short-axis views in 27 patients with non-obstructive HCM and 25 healthy volunteers. Eight equiangular points on the endo-myocardium at end-diastole were placed in each view, and the movements of these points were automatically tracked using a two-dimensional echocardiographic tissue tracking system. Time-LV radial shortening curves were obtained and averaged. The time intervals from the aortic valve closure to the point of the first 40% of peak lengthening (T_<40>) were measured in each view. RESULTS : The time difference in the T_<40> between the apex and base (Δ-T_<40>) in the HCM group was greater than that in the control group. There were good linear correlations between the Δ-T_<40> and the LV early diastolic echo-parameters and the LV mass index. CONCLUSIONS : Our results suggested that apical non-uniformity resulted in loss of active mechanical coordination of apex-to-basal lengthening, which could contribute to global LV diastolic impairment.

方法：我们获得了27例非目标HCM和25名健康志愿者的患者的基本和顶型LV短轴视图。在每个视图中放置了末端侧孔的八个相等点的八个相等点，并使用二维超声心动图组织跟踪系统自动跟踪这些点的运动。获得时间LV径向缩短曲线并平均。在每个视图中测量了从主动脉瓣关闭到峰值延长的前40％（T_ <40>）的时间间隔。结果：HCM组中最高和基数（δ-T_ <40>）之间T_ <40>的时间差大于对照组中的时间差。 δ-T_ <40>与LV早期舒张期回声参数与LV质量指数之间存在良好的线性相关性。结论：我们的结果表明，根尖的非均匀性导致顶端到基质延长的主动机械协调丧失，这可能导致全球LV舒张性损害。

项目成果

左室充満圧評価における左室流入血流速度と僧帽弁輪速度の拡張期時相解析の有用性 : Dual Doppler Systemを用いた検討

左心室流入速度和二尖瓣环速度的舒张期分析在评估左心室充盈压中的有用性：使用双多普勒系统的研究

• 发表时间: 2008
• 作者: 柴田攻;和田靖明
• 通讯作者: 和田靖明

経胸壁3次元心エコーによる大動脈弁輪径計測の有用性。断層心エコー、マルチスライスCTとの比較

使用经胸三维超声心动图测量主动脉瓣环直径的有用性。

• 发表时间: 2010
• 作者: 木原千景;村田和也;和田靖明;奥田真一;田中健雄;内田耕資;須佐建央;松崎益徳
• 通讯作者: 松崎益徳

心不全で拡張機能評価が役に立った症例とそのポイント。

舒张功能评估对心力衰竭有用的案例及其要点。

• 发表时间: 2009
• 作者: 村田和也

Left ventricular Apical Rotation, but not Basal Rotation Contributes to Twist in Normal Subjects : Evaluation by a Novel Automated Three Dimensional wall Motion Tracking Technique.

左心室心尖旋转而非基础旋转导致正常受试者扭曲：通过新型自动三维壁运动跟踪技术进行评估。

• 发表时间: 2009
• 作者: Takeo Tanaka;Kazuya Murata;Chikage Kihara;Hiroko Yoshino;Yoshio Nose;Takehisa Susa;Shinichi Okuda;Yasuaki Wada;Masunori Matsuzaki
• 通讯作者: Masunori Matsuzaki

成長と老化。血管と老化

生长和衰老。

• 发表时间: 2008
• 作者: 森岡多佳子;Yasuaki Wada;中原広道;村田和也
• 通讯作者: 村田和也