Search for useful biomarkers in bone and soft tissue tumors using global expression analysis

使用全局表达分析寻找骨和软组织肿瘤中有用的生物标志物

基本信息

项目摘要

In the current study a number of novel prognostic factors and factors determining the biological characteristics of gastrointestinal stromal tumor (GIST), Ewing's sarcoma, and synovial sarcoma were identified. For GIST, a novel prognostic marker "pfetin" was identified on 2D-DIGE, and its usefulness was verified by performing immunostaining for samples from multiple facilities. As for Ewing's sarcoma, "nucleophosmin" was identified as a novel prognostic marker.
在当前的研究中,确定了许多新的预后因素和决定胃肠道间质瘤(GIST)、尤文氏肉瘤和滑膜肉瘤生物学特征的因素。对于 GIST,在 2D-DIGE 上鉴定出了一种新的预后标记物“pfetin”,并通过对多个设施的样本进行免疫染色验证了其有效性。对于尤文氏肉瘤,“核磷蛋白”被确定为一种新的预后标志物。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
骨・軟部腫瘍の臨床診断
骨与软组织肿瘤的临床诊断
  • DOI:
  • 发表时间:
    2008
  • 期刊:
  • 影响因子:
    0
  • 作者:
    山田健志;杉浦英志;谷田部恭;川井章
  • 通讯作者:
    川井章
Association of a missense single nucleotide polymorphism, Cys1367Arg of the WRN gene, with the risk of bone and soft tissue sarcomas in Japan
  • DOI:
    10.1111/j.1349-7006.2007.00692.x
  • 发表时间:
    2008-02-01
  • 期刊:
  • 影响因子:
    5.7
  • 作者:
    Nakayama, Robert;Sato, Yasunori;Kawai, Akira
  • 通讯作者:
    Kawai, Akira
Expression of Bone Morphogenetic Proteins in Giant Cell Tumor of Bone.
骨形态发生蛋白在骨巨细胞瘤中的表达。
  • DOI:
  • 发表时间:
    2009
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Naoko Kudo;Akira Ogose;Takashi Ariizumi;Hiroyuki Kawashima;Tetsuo Hotta;Hiroshi Hatano;Tetsuro Morita;Masaki Nagata;Yukie Siki;Akira Kawai;Yuko Hotta;Makiko Hoshino;Naoto Endo.
  • 通讯作者:
    Naoto Endo.
Functional genome screen for therapeutic targets of osteosarcoma
  • DOI:
    10.1111/j.1349-7006.2009.01310.x
  • 发表时间:
    2009-12-01
  • 期刊:
  • 影响因子:
    5.7
  • 作者:
    Yamaguchi, Umio;Honda, Kazufumi;Yamada, Tesshi
  • 通讯作者:
    Yamada, Tesshi
Clinical outcome of patients with Ewing sarcoma family of tumors of bone in Japan
日本尤文肉瘤家族骨肿瘤患者的临床结果
  • DOI:
  • 发表时间:
    2007
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Hideto Obata;Akira Kawai;etc,
  • 通讯作者:
    etc,
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KAWAI Akira其他文献

Improvement in the Physical Function and Quality of Life through Exercise and Physical Activity Intervention Using a Smartphone after Allogeneic Hematopoietic Cell Transplantation: A Case Report
异体造血细胞移植后通过智能手机锻炼和身体活动干预改善身体功能和生活质量:病例报告
  • DOI:
    10.1298/ptr.e10196
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    0
  • 作者:
    FUKUSHIMA Takuya;TANAKA Takashi;FUKUSHIMA Suguru;WATANABE Mizuki;AOKI Jun;ITO Ayumu;INAMOTO Yoshihiro;KIM Sung-Won;KAWAI Akira;FUKUDA Takahiro
  • 通讯作者:
    FUKUDA Takahiro

KAWAI Akira的其他文献

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{{ truncateString('KAWAI Akira', 18)}}的其他基金

A Proposal of Parking Guidance to Minimize Parking Time and Walking Time in Large Parking Facility
大型停车场尽量减少停车时间和步行时间的停车引导提案
  • 批准号:
    19K04393
  • 财政年份:
    2019
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Study of line edge roughness (LER) reduction in 15nm scale gate pattern
15nm 规模栅极图案中线边缘粗糙度 (LER) 降低的研究
  • 批准号:
    23360150
  • 财政年份:
    2011
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Development of growth control device by interposing pH control system
开发插入pH控制系统的生长控制装置
  • 批准号:
    23656235
  • 财政年份:
    2011
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
Resist pattern development in 25nm size by condensation control in nanometer scale
通过纳米级的凝结控制,形成 25nm 尺寸的抗蚀剂图案
  • 批准号:
    19360157
  • 财政年份:
    2007
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Research on the Factor that Determines Susceptibility to Chemotherapy for Musculoskeletal Sarcoma by Genomic/Proteomic Analysis
基因组/蛋白质组分析决定肌肉骨骼肉瘤化疗敏感性的因素
  • 批准号:
    17591604
  • 财政年份:
    2005
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Development of micro resist patterns less than 35nm size based on interaction control among polymer, aggregates.
基于聚合物、聚集体之间的相互作用控制,开发尺寸小于 35nm 的微抗蚀剂图案。
  • 批准号:
    16360171
  • 财政年份:
    2004
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Adhesion and cohesion analysis of resist micro patterns less than 100nm by using atomic force microscope
利用原子力显微镜分析小于100nm抗蚀剂微图案的附着力和内聚力
  • 批准号:
    13650373
  • 财政年份:
    2001
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Study for adhesion analysis of resist pattern of 0.1μm line-width by using atomic force microscope tip
原子力显微镜针尖对0.1μm线宽光刻胶图形附着力分析研究
  • 批准号:
    10650332
  • 财政年份:
    1998
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Microbiochemical Studies on the Oxygen Deficient Layer in Inland Fish-farm Water Regions
内陆养鱼场水域缺氧层的微生物化学研究
  • 批准号:
    61560241
  • 财政年份:
    1986
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for General Scientific Research (C)

相似海外基金

Comprehensive gene expression analysis for serrated lesions of the colon to elucidate the risk of malignant transformation.
对结肠锯齿状病变进行全面的基因表达分析,以阐明恶性转化的风险。
  • 批准号:
    20K16980
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Creation of precision medicine for aortic disease by comprehensive gene analysis
综合基因分析打造主动脉疾病精准医疗
  • 批准号:
    19K09254
  • 财政年份:
    2019
  • 资助金额:
    $ 2.91万
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Search for novel biomarkers of heart failure by comprehensive genetic analysis of autopsy heart
通过尸检心脏的综合遗传分析寻找心力衰竭的新型生物标志物
  • 批准号:
    18K07011
  • 财政年份:
    2018
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Development of diagnosis and identification of therapeutic targets by elucidating the differentiation mechanism of poor prognosis subtype in lung adenocarcinoma
通过阐明肺腺癌不良预后亚型的分化机制,发展诊断和确定治疗靶点
  • 批准号:
    17K16605
  • 财政年份:
    2017
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
Elucidation of pathogenesis of Hunner type interstitial cystitis based on genomic exploration for immunological inflammation and epithelial denudation
基于免疫炎症和上皮剥脱的基因组探索阐明Hunner型间质性膀胱炎的发病机制
  • 批准号:
    17H06639
  • 财政年份:
    2017
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Research Activity Start-up
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