Assessment of Gastric Motor Function by Cine Magnetic Resonance Imaging

电影磁共振成像评估胃运动功能

• 批准号: 18591480
• 负责人: NAKAJIMA Jun
• 金额: $ 1.79万
• 依托单位: Iwate Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2007
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18591480/
• 关键词: MRI; gastric motility; gastric emptying; mosapride citrate; pylorus-preserving gastrectomy; 幽門保存胃切除術; 幽門輪温存膵頭十二指腸切除術; cineMRI; cine MRI; 胃蠕動運動

Background and Goals: The aim of this study was to evaluate the gastric motor function by magnetic resonance imaging (MRI), and it investigated whether this examination is a useful tool for therapeutic efficacy or postoperative gastric motor function.Methods: Twenty-five healthy volunteers and 10 gastric cancer patients with pylorus-preserving gastrectomy (PPG) underwent cine-MRIs. Gastric volume was determined by 3D-volumetry. Gastric motility was quantified by calculating the gastric motility index (GMI).Results: The image acquisition and analysis were successfully performed for all subjects. In healthy volunteers, the mean frequency, amplitude, velocity of gastric peristaltic waves, and GMI 30 minutes after the intake of jelly were 3/min, 8.8mm, 2.2mm/s, and 19.6mm2/s, respectively. The mean amplitude (8.8 vs. 10.4 mm, p=0.027), velocity (2.2 vs.2.6 mm/s, p<0.001) of peristaltic waves, GMI (19.6 vs.26.7 mm2/s, p<0.001), and gastric emptying rate (18.2vs.27.5%, p=0.004) significantly increased at 30 minutes after mosapride citrate administration. PPG patients with postprandial symptoms were observed having antiperistalsis-like contraction waves and reflux of gastric contents from the pyloric region into the upper part of the stomach. The mean gastric emptying rate in PPG patients with postprandial symptoms at 30 minutes after the intake of jelly tended to be less than in those without such symptoms(9.9vs.22.1%).Conclusions: The present study demonstrates that cine-MRI is a sensitive and noninvasive imaging technique for simultaneously measuring gastric motility and emptying.

背景和目标：本研究的目的是通过磁共振成像（MRI）评估胃运动功能，并探讨该检查是否是治疗效果或术后胃运动功能的有用工具。方法：25名健康志愿者10 名接受保留幽门胃切除术 (PPG) 的胃癌患者接受了电影 MRI。通过 3D 容量法测定胃体积。通过计算胃动力指数（GMI）来量化胃动力。结果：所有受试者的图像采集和分析均成功进行。健康志愿者摄入果冻后30分钟胃蠕动波的平均频率、振幅、速度和GMI分别为3次/分钟、8.8毫米、2.2毫米/秒和19.6毫米2/秒。蠕动波的平均振幅（8.8 vs. 10.4 mm，p=0.027）、速度（2.2 vs.2.6 mm/s，p<0.001）、GMI（19.6 vs.26.7 mm2/s，p<0.001）和胃排空率 (18.2vs.27.5%, p=0.004) 在 30 分钟后显着增加枸橼酸莫沙必利给药。出现餐后症状的 PPG 患者出现抗蠕动样收缩波，胃内容物从幽门区反流至胃上部。进食果冻后30分钟有餐后症状的PPG患者的平均胃排空率往往低于无餐后症状的患者（9.9%vs.22.1%）。结论：本研究表明，电影MRI是一种敏感的胃排空率。以及同时测量胃动力和排空的无创成像技术。

项目成果

Cine MR画像による胃運動機能評価の試み

尝试使用 Cine MR 图像评估胃运动功能

• 发表时间: 2007
• 作者: 伊佐地秀司;加藤宏之;ほか;伊佐地秀司(分担);伊佐地秀司(分担);馬場誠朗;Shigeaki Baba;中嶋 潤
• 通讯作者: 中嶋 潤

Cine MRイメージを用いた術後胃運動機能の評価

使用 Cine MR 图像评估术后胃运动功能

• 发表时间: 2007
• 作者: 伊佐地秀司;加藤宏之;ほか;伊佐地秀司(分担);伊佐地秀司(分担);馬場誠朗;Shigeaki Baba;中嶋 潤;Jun Nakajima;中嶋 潤;中嶋 潤
• 通讯作者: 中嶋 潤

Cine Magnetic Resonance Imaging for Assessment of Gastric Motor Function after Gastrectomy

电影磁共振成像评估胃切除术后胃运动功能

• 发表时间: 2007
• 作者: 伊佐地秀司;加藤宏之;ほか;伊佐地秀司(分担);伊佐地秀司(分担);馬場誠朗;Shigeaki Baba;中嶋 潤;Jun Nakajima;中嶋 潤;中嶋 潤;Jun Nakajima
• 通讯作者: Jun Nakajima

Assessment of gastric motor function by cine magnetic resonance imaging

• DOI: 10.1111/j.1440-1746.2009.05891.x
• 发表时间: 2009-08-01
• 期刊: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
• 影响因子: 4.1
• 作者: Baba, Shigeaki;Sasaki, Akira;Wakabayashi, Go
• 通讯作者: Wakabayashi, Go

消化器外科術後の胃運動機能評価としてのcine MRIの可能性について

电影 MRI 评估胃肠手术后胃运动功能的可能性

• 发表时间: 2007
• 作者: 伊佐地秀司;加藤宏之;ほか;伊佐地秀司(分担);伊佐地秀司(分担);馬場誠朗
• 通讯作者: 馬場誠朗