Early diagnosis of myocardial ischemia using magnetocardiogram

心磁图早期诊断心肌缺血

基本信息

批准号：
18590532
负责人：
NOMURA Masahiro
金额：
$ 2.51万
依托单位：
The University of Tokushima
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2006
资助国家：
日本
起止时间：
2006 至 2007
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18590532/
关键词：
magnetocardiogram current density map abnormal electrical current isopotential map early diagnosis myocardial infarction ischemic vector myocardial ischemia

项目摘要

We investigated the issue of whether the current density map method, in which cardiac current is estimated from the magnetic gradient, facilitates the visualization of cardiac current undetectable by ECG.1) Evaluation of an infarction vectorOld inferior myocardial infarctions (MI group) and normal healthy subjects (Normal group) were recorded using magnetocardiometer. The electromotive force of the heart was estimated from a current density map. In the current density map of the ventricular depolarization phase, multiple current densities were deduced from magnetocardiograms of the ventricular depolarization phase in the MI group, unlike normal subjects. In 4 patients in the MI group, multiple current sources were suggested, which were not detected in a body surface electrocardiogram. Magnetocardiogram is capable of permitting infarct electromotive forces to be detected, which could not be deduced from electrocardiography data.2) Detection of cardiac current undetectable by electrocard … More iography using magnetocardiography in various cardiac diseasesThe subjects were 50 healthy adults (N group), 40 patients with left ventricular overloading (LVO group), 15 patients with right ventricular overloading (RVO group), 10 patients with an old inferior myocardial infarction (OMI group), and 30 patients with diabetes mellitus (DM group). MCGs were recorded with a second derivative superconducting quantum interference device (SQUID) gradiometer using liquid helium. Isopotential maps and current density maps from unipolar precordial ECG leads and MCGs, respectively, were prepared, and the cardiac electric current was examined. The current density map at the ventricular depolarization phase showed one peak of current density in the N group. However, in the OMI group, the current density map showed multiple peaks of current density areas. In the RVO group, two peaks of current densities were detected at the right superior region and left thoracic region and these two diploles appeared to be from the right and left ventricular derived cardiac currents, respectively. Moreover, there was a significant correlation between the magnitude of the current density from the right ventricle and the systolic pulmonary arterial pressure. The current density map at the ventricular repolarization phase in the N group showed only a single current source. However, abnormal current sources in the current density maps were frequently detected even in patients showing no abnormalities on isopotential maps in the LVO, DM, and OMI groups.Our results suggest that MCG with a current density map is useful for detecting cardiac current undetectable by ECG in an early stage. Less

我们研究了电流密度图方法，其中从磁性梯度估算了心脏电流的可视化。估计的密度图。要进行挖掘Rdiography Data .2）电脑无法检测到心脏电流的检测……更多的Iography磁心电标志是50名健康成年人（N组），40例患有左心室过载（LVO组）的患者，10例患有旧的心肌梗死的患者（ OMI组和30例糖尿病患者（DM组）。检查的tricular去极化阶段在n组中显示了一个峰值，在RVO组中显示了当前密度的多个峰。此外，N组的右心室和系统的重新摄入阶段的幅度仅显示出单个电流源。 OMI结果表明，使用电流密度图的MCG用于检测Cardiaac电流的电流