Improvement of sensitivity for chemiluminescnt detection system using complex
使用复合物提高化学发光检测系统的灵敏度
基本信息
- 批准号:18550073
- 负责人:
- 金额:$ 2.57万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2006
- 资助国家:日本
- 起止时间:2006 至 2007
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The chemiluminescent reaction of tris(2,2'-bipyridine)ruthenium(III) with various compounds was examined. Five-membered heteroaromatic compounds produced intense emission. The chemiluminescent intensity increased with an increase in electron density of the aromatic ring. Aliphatic secondary amines having a carboxyl group at the α-position showed very intense chemiluminescence. The chemiluminescent reaction of tris(2,2'-bipyridine)ruthenium(III) with 2,5-dimethylthiophene was examined in detail. Tris(2,21-bipyridine)ruthenium(III) reacted with 2,5-dimethylthiophene in the ratio of 2:1. The reaction product was identified as 5-methyl-2-thiophenecarbaldeyde. From the simultaneous measurement of the chemiluminescent intensity and the oxidation potential and previously reported studies on the oxidative reaction of thiophene derivatives, the chemiluminescent reaction mechanism involving deprotonation was estimated. Since imino acids in human body fluid are important biomakers for various ill … More nesses, a sensitive simultaneous determination method for imino acids in human serum was developed. Four imino acids were successfully determined within 60 min.To develop novel co-reactants for electrochemiluminesecence (ECL) immunoassays, preliminary studies on the tris(2,2'-bipyridine)ruthenium(II) ECL detection system using some compounds as co-reactants were performed. It was suggested that the sensitivity of the tris(2,2'-bipyridine)ruthenium(II)/ N,N-dipropyl-L-alanine system was comparable to that of the tris(2,2'-bipyridine)ruthenium(II)/ tripropylamine system, which has been widely used. Since N,N-dipropyl-L-alanine is a solid at ordinary temperature and its aqueous solution is neutral, it is ease of use compared to tripropylamine. A novel derivatization reagent, (2,4,5-trimethyl-3-thieny)acetic acid, for electrogenerated tris(2,2'-bipyridine)ruthenium (III) chemiluminescent detection was synthesized. Thirteen alkylphenols and bisphenol A in a mixed solution could be detected at ppb levels using high performance liquid chromatography. A sensitive determination method of phosphate in environmental water was developed. Molybdophosphate produced by the reaction of phosphate with molybdate in sulfuric acid formed an ion-pair with aliphatic tertiary amines. Phosphate was indirectly determined by the measurement of the aliphatic tertiary amines in the ion-pairs with tris(2,2'-bipyridine)ruthenium(III) chemiluminescent detection. Less
Tris(2,2'Bipyridine)与各种化合物的主题反应产生了强烈的发射。详细检查了具有2,5的二甲基噻吩的化学发光(III)。强度和氧化和先前报道的研究。 - 用于使用某些化合物的Tris(2,2'Bipyridine)ruthenium(II)ECL检测系统的电化学(ECL)免疫测定,初步研究,使用某些化合物进行了共反应。 - 二吡啶)钌(II)/ N,N-二吡基-L-丙氨酸系统是可比的Tri S(2,2'-二吡啶)ruthenium(II))/ tripropylamine System,已广泛使用 - alan an ats al Atsolid ATS水溶液是中性的,与三甲基4,5-三甲基-3-噻纪乙酸相比,它可以在检测到的混合溶液中进行13个烷基苯酚A乙酸。在PPB水平上使用高性能液相色谱法。 )氟化学检测较少
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Novel Derivatization Reagent, (2,4,5-Trimethyl-3-thienyl) acetic Acid, for Electrogenerated Tris (2,2'-bipyridine) ruthenium (III) Chemiluminescence Detection
新型衍生试剂(2,4,5-三甲基-3-噻吩基)乙酸,用于电生成三(2,2-联吡啶)钌 (III) 化学发光检测
- DOI:
- 发表时间:2008
- 期刊:
- 影响因子:0
- 作者:T.;Tsuruta;Hitoshi KODAMATANI
- 通讯作者:Hitoshi KODAMATANI
Electrogenerated chemiluminescence detection of tris(2,2'-bipyridine)ruthenium(II)using thiophene derivatives as co-ectants
以噻吩衍生物为助剂的电化学发光检测三(2,2-联吡啶)钌(II)
- DOI:
- 发表时间:2006
- 期刊:
- 影响因子:0
- 作者:Hitoshi;Kodamatani.;Keiitsu;Saito.;Shigeo;Yamazaki.;Yu;Komatsu
- 通讯作者:Komatsu
ルテニウム錯体を用いたヘテロ芳香環化合物の化学発光検出(3)-アルキルフェノール類分析への応用
使用钌络合物化学发光检测杂芳族化合物 (3) - 在烷基酚分析中的应用
- DOI:
- 发表时间:2006
- 期刊:
- 影响因子:0
- 作者:Kato;N.;Morimoto;S.;Manabe;T;齊藤惠逸
- 通讯作者:齊藤惠逸
Chemiluminescence detection of phosphate using ion-pair extraction
使用离子对萃取化学发光检测磷酸盐
- DOI:
- 发表时间:2006
- 期刊:
- 影响因子:0
- 作者:Nanami;Ota.;Hitoshi;Kodamatani.;Kaoru;Fujinaga.;Yu;Komatsu.;Shigeo;Yamazaki.;Keiitsu;Saito
- 通讯作者:Saito
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
SAITO Keiitsu其他文献
SAITO Keiitsu的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('SAITO Keiitsu', 18)}}的其他基金
Construction of systems for safety assessment of chemical substances with luminescence
化学物质发光安全评价体系构建
- 批准号:
25502002 - 财政年份:2013
- 资助金额:
$ 2.57万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
相似国自然基金
靶向肿瘤hnRNPA2/B1的化学发光探针构建及应用研究
- 批准号:22307051
- 批准年份:2023
- 资助金额:30 万元
- 项目类别:青年科学基金项目
基于热控电极原位温度调制的比率型电化学发光传感器的构建及应用
- 批准号:22364003
- 批准年份:2023
- 资助金额:32 万元
- 项目类别:地区科学基金项目
靶向识别食品中农兽药残留的双源驱动式电化学发光可控传感体系构筑及机理研究
- 批准号:32372433
- 批准年份:2023
- 资助金额:50 万元
- 项目类别:面上项目
单原子催化剂类酶活性调控的多元化学发光分析体系的构筑
- 批准号:22374143
- 批准年份:2023
- 资助金额:50 万元
- 项目类别:面上项目
离子-π作用增强电致化学发光的机理研究及分析平台构建
- 批准号:22374007
- 批准年份:2023
- 资助金额:50 万元
- 项目类别:面上项目
相似海外基金
1,2-Dioxetanes for Quantitative Chemiluminescence Imaging
用于定量化学发光成像的 1,2-二氧杂环丁烷
- 批准号:
2155170 - 财政年份:2022
- 资助金额:
$ 2.57万 - 项目类别:
Continuing Grant
Biomolecular Infrastructure for Detection of Radioisotopes, Fluorescence, Chemiluminescence
用于检测放射性同位素、荧光、化学发光的生物分子基础设施
- 批准号:
RTI-2023-00416 - 财政年份:2022
- 资助金额:
$ 2.57万 - 项目类别:
Research Tools and Instruments
Development of a determination method for organic nitrogen compounds using photochemical reaction and chemiluminescence detection
光化学反应与化学发光检测有机氮化合物测定方法的建立
- 批准号:
21K18753 - 财政年份:2021
- 资助金额:
$ 2.57万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
Precise measurement of bioluminescence and chemiluminescence reaction quantum yield
生物发光和化学发光反应量子产率的精确测量
- 批准号:
21K05321 - 财政年份:2021
- 资助金额:
$ 2.57万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Catalyst: Chemiluminescence, Quantum Yield and High-Dimensional Data Analysis in Trajectory Surface Hopping Simulation
催化剂:弹道表面跳跃模拟中的化学发光、量子产率和高维数据分析
- 批准号:
2100971 - 财政年份:2021
- 资助金额:
$ 2.57万 - 项目类别:
Standard Grant