The Research for Excretion of Uremic Toxins & Kidney Function post Renal Transplantation.

尿毒症毒素排泄研究

• 批准号: 02670703
• 负责人: YAMADA Yutaka
• 金额: $ 1.09万
• 依托单位: Yamanashi Medical College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1990
• 资助国家: 日本
• 起止时间: 1990 至 1991
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02670703/
• 关键词: Renal Transplantation; High Liquid Chromatography; Uremic Toxins; Renal Preservation; 賢移植; 賢不全物質; 賢保存

In clinical renal transplantation, it is an essential to research for the indicator of viability about preserved kidney. Speaking about the present Japanese clinical transplantation, there are a few cases of cadaveric renal transplants.Therefore we have to injure to a grafted kidney as little as possible.We'll try to find out which is a suitable for the measurement of physical & chemical analysis as a viability indicator. That is the evaluation of Cellular Impedance. It is suggested to result in the possibility of viability for preserved kidney.And at the same time by liquid chromatographic analysis it is revealed to be a special peak pattern in acute rejection after renal transplantation. But we cannot describe whether this material is done as any uremic toxins for human beings. It might be considered for humans as any unnecessary material.

在临床肾移植中，对保存肾存活指标的研究至关重要。就目前日本临床移植而言，尸体肾移植的案例很少。因此我们必须尽可能少地对移植肾造成伤害。我们会尝试找出适合理化测量的方法。分析作为生存能力指标。这就是细胞阻抗的评估。提示存在保留肾存活的可能性。同时液相色谱分析显示其为肾移植后急性排斥反应的特殊峰型。但我们无法描述这种物质是否被当作任何人类尿毒症毒素。对于人类来说，它可能被视为任何不必要的材料。