Treatment of dentin hypersensitivity and dental caries by ammonium hexafluorosilicate

六氟硅酸铵治疗牙本质过敏和龋齿

基本信息

批准号：
13672002
负责人：
SUGE Toshiyuki
金额：
$ 2.24万
依托单位：
Tokushima University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2001
资助国家：
日本
起止时间：
2001 至 2002
项目状态：
已结题

项目摘要

Diamine silver fluoride is clinically used to prevent progress of dental caries in Japan. However, diamaine silver fluoride stains teeth black due to silver sulfide precipitation. To solve this drawback, we prepared ammonium hexafluorosilicate which dose not stain teeth, and we found ammonium hexafluorosilicate increased crystallinity of apatite powder and formed lager amount of fluoridated apatite when compared with acidulated phosphate fluoride (APF) or diamine silver flioride. The aim of this study was to evaluate whether or not ammonium hexafluorosilicate increase acid resistance of bovine enamel and dentin. Bovaine enamel and dentin ware embedded into resin leaving labial side exposed. The polished surface was divided into several portions using paraffin wax and each portion was treated with a fluoride solution (ammonium hexafluorosilicate, diamine silver fluoride, APF or NaF) for 3 min. after the fluoride solutions were washed out with distilled water, the tooth was immersed in d … More emineralization solution for 24 hours. The depth of demineralized tooth was measured with surface roughness analyzer. Also, the demineralized specimens were subjected microradiography. In the enamel specimens, demineralized depth after treated with ammonium hexafluorosilicate (81.6%) or diamine silver fluoride (83.7%) was significantly shallower than that of control {98.6^^+__- 40.0um(100%)}. Treatment with APF or NaF did not reduce the depth significantly. All fluoride solutions reduced the depth than that of control in dentin specimens. Diamine silver fluoride (75.5%) and ammonium hexafluorosilicate (85.2%) treatments showed greater acid resistance than the layer formed after ammonium hexafluorosilicate od diamine silver fluoride treatment prevented progress of demineralization. We concluded that ammonium hexafluorosilicate is useful to prevent enamel and caries since ammonium hexafluorosilicate trearment increased acid resistance of enamel and dentin without changing the color of tooth. Less

在日本，二胺氟化银在临床上用于预防龋齿的进展，但是，二胺氟化银会因硫化银沉淀而使牙齿变黑。为了解决这个问题，我们制备了不会染色牙齿的六氟硅酸铵，我们发现六氟硅酸铵增加了。与酸化磷酸氟化物（APF）或二胺银相比，磷灰石粉末的结晶度更高，并且形成更多的氟化磷灰石本研究的目的是评估六氟硅酸铵是否能提高牛牙釉质和牙本质的耐酸性，将牛牙釉质和牙本质器皿嵌入树脂中，使唇侧暴露，并使用石蜡将抛光表面分成几个部分。氟化后，用氟化物溶液（六氟硅酸铵、二胺氟化银、APF或NaF）处理部分3分钟。用蒸馏水冲洗牙齿，将牙齿浸入脱矿溶液中24小时，用表面粗糙度分析仪测量脱矿牙齿的深度，并对牙釉质标本进行显微射线照相。经六氟硅酸铵(81.6%)或二胺氟化银(83.7%)处理后明显浅于对照{98.6^^+__- 40.0um(100%)}。使用 APF 或 NaF 处理后，所有氟化物溶液均比氟化二胺银 (75.5%) 和铵的对照深度减少。六氟硅酸盐 (85.2%) 处理显示出比六氟硅酸铵或二胺氟化银处理后形成的层更高的耐酸性，防止了我们得出的结论是，六氟硅酸铵可有效预防牙釉质和龋齿，因为六氟硅酸铵处理可提高牙釉质和牙本质的耐酸性，而不会改变牙齿的颜色。