Evaluation of intraportal venous flow distribution by unenhanced MR angiography using tagging pulse

使用标记脉冲通过非增强磁共振血管造影评估门静脉内血流分布

基本信息

批准号：
13670943
负责人：
ITO Katsuyoshi
金额：
$ 1.54万
依托单位：
Yamaguchi University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2001
资助国家：
日本
起止时间：
2001 至 2002
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13670943/
关键词：
Superior mesenteric venous flow Splenic venous flow Hepatic cirrhosis Portal venous flow distribution Unenhanced MR angiography Tagging pulse MRI 門脈血流

项目摘要

Portal flow imaging using unenhanced MR angiography techniques was performed for normal subjects to evaluate the intraportal venous flow distribution from the superior mesenteric vein and the splenic vein. At first, unenhanced MR angiographic images without using tagging pulse were obtained as referenced images of the portal vein. In these images, the portal vein is shown as high signal intensity. Then, tagging pulse was placed on the superior mesenteric vein to suppress the inflow signal from the superior mesenteric vein. As a result, the superior mesenteric venous inflow is demonstrated as areas of decreased signal in the portal vein. The same technique was applied to the splenic vein. In this study, we showed that the superior mesenteric venous flow mainly entered into the right side of the main portal vein forming the streamlined flow while the splenic venous flow mainly entered into the left side of the main portal vein in the normal subjects.As the next analysis, we evaluated the … More influence of fasting and food intake for the portal flow dynamics. In this study, we revealed that the portal vein was predominantly perfused by the splenic venous flow before meal while it was predominantly perfused by the superior mesenteric venous flow after meal. Additionally, the superior mesenteric venous flow dramatically increased after meal compared with the fasting state while the splenic venous flow decreased in 41%, increased in 31% and showed no change in 28% of the subjects.In clinical study, we evaluated the pattern of the intraportal venous flow distribution in cirrhotic patients. In cirrhotic patients, we sometimes observed the superior mesenteric venous flow entering into the left side of the main portal vein and the splenic venous flow entering into the right side of the main portal vein forming the streamlined flow. Additionally, the reversed flow from the superior mesenteric vein into the splenic vein can be observed in cirrhotic patients. These facts indicate that portal venous flow dynamics in cirrhotic patients may be different from that in normal subjects. Less

对正常受试者进行门户流量的MR技术，以评估上肠内静脉的静脉内流动利用率。高信号强度。将静脉脉冲放置在上肠静脉上的上级静脉。静脉流动时，脾静脉流在正常受试者中主要输入主要的门户。在脾气暴躁的同时，在肠肠内静脉流动后，肠系膜上的静脉流量急剧增加，而脾脏静脉流则与状态相比，脾脏静脉流量急剧增加，而脾脏静脉流则在31％的41％NCRED中降低，而在31％降低了，则肠系膜上的静脉流急切地增加了，而没有炎症，则在41％的饮食中，肠系膜上的静脉流急剧增加。在临床研究中，有28％的受试者。在肝硬化的静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉静脉动态动力学。