Osteoporosis-evaluation with MR imaging-

骨质疏松症-磁共振成像评估-

• 批准号: 08670993
• 负责人: YOSHIKAWA Hiroyuki
• 金额: $ 1.34万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1996
• 资助国家: 日本
• 起止时间: 1996 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08670993/
• 关键词: osteoporosis; MRI; T2^*; T2^★; 骨粗髪症

Osteoporosis is characterized by demineralization of bone matrix, and T2^* will be prolonged due to diminution of susceptibility. The purpose of this study is to evaluate osteoporosis with MR imagint. MR images of the lumbar spine were obtained with gradient echo sequence. TR was 500 msec, and TEs were 4.5,9.3,14.1 (in phase), 6.9,11.7, and 16.5 msec (out of phase). Group A was consisted with 13 patients administered steroids for collagen disease, and group B was composed with 11 patients without steroids. T2^* was calculated from the decline of signal intensity - TE line. Mean T2^* values of patients with and without steroid therapy were 0.014 and 0.013, respectively, and there was no significant difference between these two groups. Bone matrix could not be evaluated with these methods.

骨质疏松症的特征是骨基质的脱矿化，由于易感性的降低，T2^*将延长。这项研究的目的是通过MR Imaint评估骨质疏松症。用梯度回声序列获得腰椎的MR图像。 TR为500毫秒，TES为4.5,9.3,14.1（相位），6.9,11.7和16.5毫秒（过期）。 A组由13例服用类固醇的患者组成，用于胶原蛋白疾病，B组由11例没有类固醇的患者组成。 T2^*是根据信号强度-TE线的下降计算得出的。接受和不接受类固醇治疗的患者的平均T2^*值分别为0.014和0.013，这两组之间没有显着差异。这些方法无法评估骨基质。