Studies on the Safety of Cyanoglucosides in Vegetables.

蔬菜中氰基葡萄糖苷的安全性研究。

• 批准号: 01580075
• 负责人: OHTSURU Masaru
• 金额: $ 1.15万
• 依托单位: Yamaguchi Women's University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01580075/
• 关键词: Thyroid gland; Goiter; Cruciferae plant; Cyanoglucosides; Iodine; konbu; Seaweed; カラシ油; キャベツ; 大根

Cyanoglucosides (glucosinolates), contained in plants of Cruciferae family (ex. rape, radish, cabbage, mustard & wasabi etc.), have a strong goitrogenic activity and inhibit the growth of animals.This study was investigated on the safety of vegetables, which contained cyanoglucosides, (horse radich, cabbage and kaiware radish). The mixing of horse radish (500g), or cabbage (500g), or kaiware (250g) in feed powder (1kg) as the diet caused atrophy of the thyroid gland in rats, In the biochemical test of blood, the increase of blood lipids were observed, too. These changes were remarkable in kaiware feed. Then, the recovery effects to these symptoms caused by the vegetables were studied using seaweed (Konbu). In the case of feeding contained kaiware (250g) and Konbu (1-10g) in feed powder 1kg, these symptoms were recovered to normal level.From these results, it is considered the eating of Konbu (seaweed) is very effective to goitrogen in every meals.

十字花科植物（如油菜、萝卜、卷心菜、芥菜、山葵等）中含有的氰基葡萄糖苷（芥子油苷）具有很强的致甲状腺肿活性，并抑制动物的生长。本研究以蔬菜的安全性为研究对象，含有氰基葡萄糖苷（辣根、卷心菜和芥菜萝卜）。在饲料粉（1kg）中掺入辣根（500g）、卷心菜（500g）、芥菜（250g），引起大鼠甲状腺萎缩，血液生化检查中，血脂升高。也被观察到。这些变化在kaiware feed中是显着的。然后，使用海藻（昆布）研究了对蔬菜引起的这些症状的恢复效果。在饲料粉1kg中添加海带（250克）和昆布（1-10克）的情况下，这些症状恢复到正常水平。从这些结果来看，认为食用昆布（海藻）对甲状腺肿大非常有效。每顿饭。