Developing Multiplexed COVID-19 Diagnostic Methods for Medical Surveillance

开发用于医疗监测的多重 COVID-19 诊断方法

• 批准号: 555046-2020
• 负责人: She, Zhe
• 金额: $ 3.64万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=705799
• 关键词: Developing; Multiplexed; COVID; 19; Diagnostic

COVID-19 is a highly contagious disease that poses a challenge in medical diagnosis. Rapid, accurate and portable devices are urgently needed to increase medical surveillance capability, providing point-of-care testing. Detection of COVID-19 antibodies can complement the existing techniques and provide diagnosis and population surveillance. Invention of portable glucose meters in the 1960s, followed by subsequent innovations, enabled effective analysis of blood glucose in diabetic patients without the requirement for laboratory equipment or expertise. This allowed rapid, accurate and portable analytical methodology outside of medical laboratories. Glucose meters are now readily available to the public from retail stores and the availability of the testing is sufficient to meet demand. However, this is not the case for detecting COVID-19. COVID-19 samples collected from patients can only be analyzed by medical professionals in medical laboratory settings. The objectives of this project are to develop a more portable and automated COVID-19 diagnostic methodology requiring minimum operational expertise, provide medical diagnosis and empower resource-poor communities.

COVID-19 是一种高度传染性疾病，给医学诊断带来了挑战。迫切需要快速、准确和便携式设备来提高医疗监测能力，提供即时检测。 COVID-19 抗体检测可以补充现有技术并提供诊断和人群监测。 20 世纪 60 年代便携式血糖仪的发明以及后续的创新使得无需实验室设备或专业知识即可有效分析糖尿病患者的血糖。这使得医学实验室之外的快速、准确和便携的分析方法成为可能。现在公众可以从零售店轻松获得血糖仪，并且测试的可用性足以满足需求。然而，检测 COVID-19 的情况并非如此。从患者身上收集的 COVID-19 样本只能由医学专业人员在医学实验室环境中进行分析。该项目的目标是开发一种更加便携和自动化的 COVID-19 诊断方法，需要最少的操作专业知识，提供医疗诊断并为资源匮乏的社区提供支持。