Expression of Ly6C/6G defines a novel Aire-dependent subset of medullary thymic epithelial cells with tolerogenic function

Ly6C/6G 的表达定义了具有耐受功能的髓质胸腺上皮细胞的新的 Aire 依赖性亚群

• 批准号: 26460577
• 负责人: MORIMOTO Junko
• 金额: $ 3.16万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2014
• 资助国家: 日本
• 起止时间: 2014-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26460577/
• 关键词: 自己免疫疾患; 自己寛容; 胸腺髄質上皮細胞; 中枢性寛容; 自己抗原; 胸腺; Aire

项目成果

Expression of Ly6 family protein defines a novel Aire-dependent subset of medullary thymic epithelial cells with tolerogenic function

Ly6家族蛋白的表达定义了具有耐受性功能的新型Aire依赖性胸腺髓质上皮细胞亚群

• 发表时间: 2017
• 作者: Ito K;Morimoto J;Kihara A;Matsui Y;Kurotaki D;Kanayama M;Simmons S;Ishii M;Sheppard D;Takaoka A;Uede T;α9β1 integrin acts as a critical intrinsic regulator of human rheumatoid arthritis.;Morimoto Junko
• 通讯作者: Morimoto Junko

Novel Aire-dependent tolerogenic lineage(s) of medullary thymic epithelial cells expressing Ly6 family protein

表达 Ly6 家族蛋白的髓质胸腺上皮细胞的新型 Aire 依赖性耐受谱系

• 发表时间: 2016
• 作者: Ito K;Morimoto J;Kihara A;Matsui Y;Kurotaki D;Kanayama M;Simmons S;Ishii M;Sheppard D;Takaoka A;Uede T;α9β1 integrin acts as a critical intrinsic regulator of human rheumatoid arthritis.;Morimoto Junko;Junko Morimoto
• 通讯作者: Junko Morimoto

Temporal Lineage Tracing of Aire-Expressing Cells Reveals a Requirement for Aire in Their Maturation Program

• DOI: 10.4049/jimmunol.1302786
• 发表时间: 2014-03-15
• 期刊: JOURNAL OF IMMUNOLOGY
• 影响因子: 4.4
• 作者: Nishikawa, Yumiko;Nishijima, Hitoshi;Matsumoto, Mitsuru
• 通讯作者: Matsumoto, Mitsuru

Integrin α9 on lymphatic endothelial cells regulates lymphocyte egress

• DOI: 10.1073/pnas.1311022111
• 发表时间: 2014-02-25
• 期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• 影响因子: 11.1
• 作者: Ito, Koyu;Morimoto, Junko;Uede, Toshimitsu
• 通讯作者: Uede, Toshimitsu