Developmnt of early detection of leukemia cells by employing soft computing an dielectrophoresis

利用软计算和介电泳进行白血病细胞早期检测的进展

• 批准号: 23800072
• 负责人: EGUCHI Masanori
• 金额: $ 2.08万
• 依托单位: Fuzzy Logic Systems Institute
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Research Activity Start-up
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-23800072/
• 关键词: 誘電泳動; 進行波電界; 血液細胞; 白血病; 誘電泳動現象; ソフトコンピューティング; 白血病細胞; 超早期診断

The Bottle neck Fork-Trace (BF) electrode which can transport and separate all blood cells in chamber have been developed for early detection of leukemia.The BF electrode is possible to transport all particles from the entire chamber to the electrode gap by Traveling-wave electric fields at first, and then separate them by dielectrophoresis. Leukocytes in medium were separated from erythrocytes by using the electrode. The dielctrophoretic characteristics of leukemia cells (HL-60, BALL-1) were measured, and the leukemia cells were separated form normal leukocytes by difference in dielectric property.

已经开发出可以运输和分离的所有血细胞的瓶颈叉轨道（BF）电极已开发出来以早期检测白血病。BF电极可以首先通过旅行波电场在整个腔室中从整个腔室传输到电极间隙，然后通过介电粒子将它们分开。使用电极与红细胞分离培养基中的白细胞。测量白血病细胞（HL-60，BALL-1）的二肠热特性，并通过介电性能差异将白血病细胞分离形成正常的白细胞。

项目成果

Separation of Particles by Combining Dielectrophoresis and Traveling-wave Electroosmosis under Inclined Gravity

倾斜重力下结合介电泳和行波电渗分离颗粒

• 发表时间: 2011
• 作者: Masanori Eguchi;Hiroko Imasato;and Takeshi Yamakawa
• 通讯作者: and Takeshi Yamakawa

Separation of Leukemia Cells from Blood by Employing Dielectrophoresis

利用介电泳从血液中分离白血病细胞

• DOI: 10.1080/10798587.2008.10643232
• 发表时间: 2012
• 期刊: Intelligent Automation and Soft Computing
• 影响因子: 2
• 作者: Hiroko Imasato;Takeshi Yamakawa;and Masanori Eguchi
• 通讯作者: and Masanori Eguchi

Separation of Blood Cells by Employing Dielectrophoresis and Traveling-wave Electric Fields

利用介电泳和行波电场分离血细胞

• 发表时间: 2012
• 作者: Masanori Eguchi;Hiroko Imasato;and Takeshi Yamakawa
• 通讯作者: and Takeshi Yamakawa

Particle Separation by Employing Non-uniform Electric Fields, Traveling-wave Electric Fields and Inclined Gravity

利用非均匀电场、行波电场和倾斜重力进行颗粒分离

• DOI: 10.1080/10798587.2008.10643231
• 发表时间: 2012
• 期刊: Intelligent Automation and Soft Computing
• 影响因子: 2
• 作者: Masanori Eguchi;Hiroko Imasato;and Takeshi Yamakawa
• 通讯作者: and Takeshi Yamakawa

誘電泳動と進行波電界を用いた血液細胞の分離

使用介电泳和行波电场分离血细胞

• 发表时间: 2013
• 作者: Hiroko Imasato;Takeshi Yamakawa;Masanori Eguchi;江口 正徳,山川 烈
• 通讯作者: 江口 正徳,山川 烈