Allotments of gustatory functions in the chorda tympani (CT), great superficial petrosal nerve (GSP) and lingual nerve (LN).

味觉功能在鼓索 (CT)、岩浅大神经 (GSP) 和舌神经 (LN) 中的分配。

• 批准号: 03454434
• 负责人: KASAHARA Yasuo
• 金额: $ 4.22万
• 依托单位: Kagoshima University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1991
• 资助国家: 日本
• 起止时间: 1991 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-03454434/
• 关键词: Taste; Soft palate; Great superficial petrosal nerve; Chorda tympani; Taste buds; Hamster; Rat; ラット; 忌避条件づけ; 味溶液摂取行動; アミロライド; ハムスタ-

To clarify the functional properties of CT.GSP or LN, neural response recording and behavioral experiments (conditioned taste aversion paradigm) were performed in the rats, hamsters and guinea pigs.From the results of these serial experiments indicated that1. GSP is important for the discrimination of sucrose taste in the hamster2. response characteristics for GSP were different from GT,3. the different receptor site or transduction mechanisms in taste buds on the soft palate from those on the tongue4. there were very very few Capsaicin, Menthol sensitive fibers in the LN5. taste buds on the soft palate have not only high responsiveness for sweet substance but also different response properties for other taste6. the degree of the aversion was significantly decreased when the GSP and/or CT were sectioned bilaterally.The order of the sectioning effects was GSP+CT > GSP (〕SY.gtoreq.〔) CT > Sham. From the results of these experiments suggest the GSP plays an important role for mediating sweet taste information.

为了阐明CT.GSP或LN的功能性能，在大鼠，仓鼠和豚鼠中进行了中性响应记录和行为实验（条件味道厌恶范式）。从这些串行实验的结果表明1。 GSP对于仓鼠中蔗糖味道的区分很重要。 GSP的响应特征与GT不同，3。舌头上的味蕾中的味蕾中的不同受体位点或翻译机制来自舌头4。 LN5中的辣椒素很少，薄荷醇敏感纤维。柔软的味蕾上的味蕾不仅对甜物质具有很高的响应能力，而且对其他味道也具有不同的响应特性6。当将GSP和/或CT分配分配时，厌恶程度显着降低。截面效应的顺序为GSP+CT> GSP（> sy.gtoreq.〜）CT> Sham。从这些实验的结果来看，GSP在介导甜味信息方面起着重要作用。

项目成果

Harada,S.: "A method to acknowledge pulse train in biological signals by a microcomputer system." Chemical Senses. 18. 335 (1993)

Harada,S.：“一种通过微计算机系统确认生物信号中的脉冲序列的方法。”

榎元 勝治: "ラット口腔内味蕾の分布と形態の発育に伴う変化." 歯科基礎医学会雑誌. 35. 116 (1993)

Katsuharu Enomoto：“发育过程中大鼠口腔味蕾的分布和形态的变化。”日本基础牙科医学会杂志 35. 116 (1993)

Kohriyama, H.: "Characteristics of the chorda tympani responses to gustatory stimuli in the guinea-pig" Chem.Senses. 18. 329 (1993)

Kohriyama, H.：“豚鼠鼓索对味觉刺激的反应特征”Chem.Senses。

Kohriyama, H.: "Characteristics of the chorda tympani responses to gustatory stimuli in the guinea-pig" Proc.Jpn.Symp.on taste & Smell. 26. 97-100 (1992)

Kohriyama, H.：“豚鼠鼓索对味觉刺激的反应特征”Proc.Jpn.Symp.on 味觉

Harada, S.: "A method to acknowledge pulse train in biological signals by a microcomputer system" Chem.Senses. 18. 335 (1993)

Harada, S.：“一种通过微计算机系统确认生物信号中的脉冲序列的方法”Chem.Senses。