On a Circulation System Monitor of HD Patient to Realize a Safe High Efficiency Dialysis (1992)

浅谈HD患者循环系统监测以实现安全高效透析（1992）

• 批准号: 02452176
• 负责人: OHTA Michio
• 金额: $ 4.1万
• 依托单位: University of Tsukuba
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1990
• 资助国家: 日本
• 起止时间: 1990 至 1991
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-02452176/
• 关键词: Hemodialysys; Patients Monitor; Pressure Drop; High Efficiency; Hematocrit; Blood Volume; Blood Pressure; Continuous Measurement; 無侵襲連続計測; レ-ザ-; ヘマトクリット計測; 血液量; 酵素飽和度; 連続計測

To realize a safe but high efficiency hemodialysis, it is inevitable to know the patient state to avoid pressure drops due to the rapid water removal. Mainly two monitor systems were developed in this research projects. One is a continuous blood volume and. oxigen saturation monitor which measures continuously. For this sistem a couple of laser photodetecting circuit including the beams of 756 and 805 nn. 805 nm beam is known to be insensitive to oxigen saturation degree of hemoglobin, which in tern measures the so called heamatocrit. From the heamatocrit relative blood volume shall be calculated continuously. 756 beam is sensitive to the oxigen saturation so as to measure the saturation degree with the conbination of of 805 beam data.Continuous measurement of blood pressure is the other of urgent problem whi we encountered in this research, because of sudden pressure drops in hemodialysis patients. Based on analysis with an electric equivalent circuit of blood circulation system, a new approach has been developed here. The result of analysis gave a simple relation between pressure measured at dialysis circuit and the brachial pressure. To put this result into a clinical use, a new dialysis circuit vas designed, which include an additional air-trap.The clinical test were fairly acceptable in usefulness and noninvasive.

为了实现安全但高效率的血液透析，不可避免地要知道患者状态以避免由于迅速去除水的压力下降。该研究项目中主要开发了两个监视系统。一个是连续的血量。氧饱和监测仪，可连续测量。对于此SISTEM，几个激光光电检测电路，包括756和805 NN的光束。已知805 nm梁对血红蛋白的氧饱和度不敏感，在Tern中，它测量了所谓的Heamatocrit。从Hematocrit相对血容量应连续计算。 756梁对氧化饱和度敏感，以便与805束数据的结合度测量饱和度。连续测量血压是我们在这项研究中遇到的紧急问题的另一个，因为血液Lysis患者的突然压力下降。基于用电气循环系统电路分析，这里已经开发了一种新的方法。分析的结果给出了在透析回路和臂压力下测得的压力之间的简单关系。为了将此结果纳入临床用途，设计了新的透析电路VAS，其中包括额外的空气捕获。

项目成果

Y.SANKAI: "Artificial Kidney Control System Based on Cybernics Conception" Artificial Organs. 14(3). 291-295 (1990)

Y.SANKAI：“基于控制学概念的人工肾脏控制系统”人工器官。

太田 道男: "人工腎臓における"ながれ"の諸問題" ながれ. 11ー1. 3-13 (1992)

Michio Ota：“人工肾‘流动’的问题”Nagare 11-1 (1992)。

Y.SANKAI: "Therapeutic Robot System aimed at Human Oriented System" Proc.of IEEE International Workshop on Intelligent Motion Control. 1. 247-251 (1990)

Y.SANKAI：“面向人类的治疗机器人系统”Proc.of IEEE 国际智能运动控制研讨会。

Y. SANKAI: "Therapeutic Robot System aimed at Human Oriented System" Proc. of IEEE International Workshop on Intelligent Motion controlProc. IEEE International Workshop on Intelligent Motion Control. 1. 247-251 (1990)

Y. SANKAI：“针对以人为本的系统的治疗机器人系统”Proc。

山海 嘉之,太田 道男,太宰 利博,熊谷 頼明: "透析中のシャント部血圧の連続計測法" 日本透析療法学会会誌. 24巻3号. (1991)

Yoshiyuki Sankai、Michio Ota、Toshihiro Dazai、Yoriaki Kumagai：“透析期间分流血压的连续测量方法”日本透析治疗学会杂志第 24 卷，第 3 期（1991 年）。