Multi-observation-port cuvette for solution scattering

用于溶液散射的多观察口比色皿

• 批准号: 24657100
• 负责人: AKIYAMA Shuji
• 金额: $ 2.66万
• 依托单位: Institute for Molecular Science
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-24657100/
• 关键词: Ｘ線; 散乱; タンパク質; Ｘ線小角散乱; 多チャンネル; セル

Small-angle x-ray scattering (SAXS) is one of the powerful methods to evaluate the size and shape of macromolecules in solution. This project aims at improving a throughput of SAXS measurements by developing a multi-observation-port cuvette. According to the experimental trials so far we made, it was technically difficult to seal many observation ports so uniformly with a large-area quartz window. Thus, we had no choice but to make an alteration to the original plan so that the samples were semi-automatically supplied to a single-port cuvette with an auto-dispensing apparatus mounted on X-Y electronically actuating devices.

小角 X 射线散射 (SAXS) 是评估溶液中大分子尺寸和形状的有力方法之一。该项目旨在通过开发多观察端口比色皿来提高 SAXS 测量的吞吐量。根据我们迄今为止所做的实验，用大面积的石英窗如此均匀地密封许多观察口在技术上是困难的。因此，我们别无选择，只能对原来的计划进行修改，将样品半自动地供应到单口比色皿中，并在X-Y电子驱动装置上安装自动分配装置。

项目成果

Small-angle x-ray Scattering Study on Cyanobacterial Clock Protein KaiC

蓝藻时钟蛋白KaiC的小角X射线散射研究

• 发表时间: 2014
• 作者: Akiyama S.

KaiC as A Circadian Pacemaker of Cyanobacterial Circadian Clock

KaiC 作为蓝藻生物钟的昼夜节律起搏器

• 发表时间: 2014
• 作者: Akiyama S.;Akiyama S.
• 通讯作者: Akiyama S.